Product Description
Our Earthworm (Pheretima) Series comprises three distinct product forms derived from cultivated earthworms – a resource with over 2,000 years of documented use in Traditional Chinese Medicine. Each form serves different applications and offers distinct bioactive profiles:
1. Earthworm Protein Powder
A highly purified, food-grade protein extract. This product is specifically processed to be free from lumbrokinase (enzyme activity) while retaining the beneficial protein and peptide content. It is produced through advanced extraction, separation, and low-temperature drying processes, yielding a clean protein source rich in essential amino acids and small-molecule peptides (MW 5,000–10,000 Da). This form is ideal for general protein supplementation, functional foods, and cosmetic applications where enzyme activity is not desired.
2. Earthworm Freeze-Dried Powder
Produced by freezing fresh earthworms at low temperatures followed by vacuum freeze-drying (lyophilization), then grinding into fine powder. This form retains the full natural bioactive profile, including lumbrokinase (fibrinolytic enzyme) activity >12,000 IU/mg. Freeze-drying is scientifically proven to be superior to traditional sun-drying or heat-drying methods, preserving heat-sensitive enzymes and bioactive peptides and maintaining natural protein structure. This form is ideal for health supplements, cardiovascular health products, and TCM formulations.
3. Earthworm Freeze-Dried Strips
Whole or cut earthworm bodies are processed using the same freeze-drying technology but without pulverization, retaining the natural morphology. This form retains the full natural bioactive profile, including lumbrokinase. It is primarily used in Traditional Chinese Medicine as decoction pieces for clinical prescriptions, where visual identification and whole-body integrity are required. It is also valued as a high-nutrition feed ingredient for aquaculture and specialty animal feed applications.
Product Comparison Table
| Feature | Earthworm Protein Powder | Earthworm Freeze-Dried Powder | Earthworm Freeze-Dried Strips |
|---|---|---|---|
| Form | Fine powder (80–100 mesh) | Fine powder (80–100 mesh) | Whole or cut bodies, natural shape retained |
| Processing | Extraction, separation, low-temp drying (enzyme removal) | Freeze-drying + pulverization | Freeze-drying only (no pulverization) |
| Lumbrokinase Activity | None (specifically removed during processing) | >12,000 IU/mg (active) | Natural profile (active) |
| Key Components | Purified proteins, amino acids, small-molecule peptides, free from enzymes | Full natural profile: lumbrokinase, collagenase, amino acids, peptides | Full natural profile: lumbrokinase, collagenase, amino acids, peptides |
| Molecular Weight | 5,000–10,000 Da | Full range | Full range |
| Food Grade | Yes | Yes | Yes |
| Primary Use | General protein supplements, functional foods, cosmetics | Cardiovascular health supplements, TCM formulations | TCM decoction pieces, clinical prescriptions, aquaculture feed |
| Target Customers | Nutraceutical companies, food manufacturers, cosmetic brands | Supplement brands, TCM pharmacies, functional food manufacturers | TCM clinics, herbal pharmacies, aquaculture farms |
Key Features & Advantages
Earthworm Protein Powder
- Clean Protein Source – Purified protein extract, specifically processed to remove enzyme activity
- Rich in Amino Acids & Peptides – Contains essential amino acids and small-molecule peptides (MW 5,000–10,000 Da)
- Highly Bioavailable – Short-chain small molecule proteins offer excellent digestibility and absorption
- Versatile Applications – Suitable for a wide range of nutraceutical, food, and cosmetic products
- Gentle & Safe – Free from enzyme activity, making it suitable for general wellness applications
Earthworm Freeze-Dried Powder
- High Lumbrokinase Activity – Standardized enzyme activity >12,000 IU/mg, supporting cardiovascular health
- Full Natural Bioactive Profile – Retains lumbrokinase, collagenase, plasminogen activator, amino acids, and trace elements
- Superior Freeze-Drying Technology – Low-temperature vacuum freeze-drying preserves heat-labile enzymes and bioactive peptides
- Proven Efficacy – Lumbrokinase is specific to fibrin and supports healthy blood viscosity and circulation
- Traditional Use – Used in TCM for thousands of years for cardiovascular and circulatory health
Earthworm Freeze-Dried Strips
- Natural Morphology Retained – Whole-body form for TCM decoction pieces and visual identification
- Full Natural Bioactive Profile – Same as freeze-dried powder, in whole-body form
- Traditional Medicine Use – Ideal for clinical prescriptions and herbal pharmacies
- Aquaculture Feed – High-nutrition ingredient for fish, shrimp, and livestock
Key Health Benefits
Earthworm Protein Powder
1. High-Quality Protein Source
Rich in essential amino acids and small-molecule peptides, supporting overall health and vitality.
2. Supports Immune Function & Tissue Repair
The amino acid profile supports immune function, tissue repair, and overall wellness.
3. Easily Absorbed
With a molecular weight range of 5,000–10,000 Da, the proteins are readily absorbed and utilized by the body.
4. Versatile Nutritional Support
Suitable for general wellness, functional foods, and cosmetic applications.
Freeze-Dried Powder & Strips
1. Supports Healthy Blood Circulation
Lumbrokinase, the primary fibrinolytic enzyme in freeze-dried earthworm products, helps maintain healthy blood flow by supporting the body's natural fibrinolytic system. It is specific to fibrin and does not cause excessive bleeding.
2. Helps Maintain Healthy Blood Viscosity
Lumbrokinase helps reduce blood viscosity, lower platelet aggregation, and support healthy blood flow.
3. Promotes Cardiovascular Wellness
The combination of lumbrokinase, collagenase, and other bioactive peptides supports the dissolution of blood clots, improves microcirculation, and helps maintain healthy blood vessels.
4. Backed by Traditional Use
Dried earthworm (Pheretima) has been used in Traditional Chinese Medicine for thousands of years to support cardiovascular and circulatory health.
Applications
| Product | Primary Applications | Secondary Applications |
|---|---|---|
| Protein Powder | • Nutraceuticals & protein supplements • Functional foods & beverages • Cosmetics & personal care |
• Infant nutrition • Sports nutrition |
| Freeze-Dried Powder | • Cardiovascular health supplements • Circulation support products • TCM formulations |
• Functional foods for cardiovascular wellness |
| Freeze-Dried Strips | • TCM decoction pieces • Clinical prescriptions |
• Aquaculture feed • Livestock feed • R&D applications |
Frequently Asked Questions (FAQ)
Q: Are the earthworms farmed or wild-caught?
A: All our earthworm products are sourced from legally cultivated earthworms raised on certified farms under controlled conditions. We do not use wild-caught earthworms. Full documentation and traceability records are available.
Q: What is lumbrokinase and why is it important?
A: Lumbrokinase is a group of fibrinolytic enzymes found naturally in earthworms. It is known for its ability to dissolve fibrin – the main protein component of blood clots. Lumbrokinase is specific to fibrin and does not cause excessive bleeding. It is present in our Freeze-Dried Powder and Strips but not in our Protein Powder.
Q: Why is freeze-drying better than traditional drying methods?
A: Comparative studies have shown that freeze-dried earthworms exhibit higher fibrinolytic and thrombolytic activities than sun-dried earthworms. Freeze-drying preserves heat-sensitive enzymes and bioactive peptides and maintains natural protein structure.
Q: Is the Protein Powder suitable for use in food products?
A: Yes. Our Earthworm Protein Powder is a food-grade product, free from lumbrokinase, and can be used as a clean protein source in health supplements, functional foods, protein bars, and beverages.
Q: Can the Protein Powder be used in cosmetic applications?
A: Yes. Earthworm Protein Powder (lumbrokinase-free) is used in cosmetic applications for its rich amino acid and peptide content, supporting skin metabolism and skin renewal.
Q: Can the Freeze-Dried Strips be used as feed?
A: Yes. Freeze-Dried Strips are valued as a high-nutrition feed ingredient for aquaculture (fish, shrimp) and livestock, providing high-quality protein and natural bioactive compounds.
Why Choose Huilin Bio-Tech?
Your Professional Manufacturing & Sourcing Partner
We are more than a supplier - we are a comprehensive supply chain partner dedicated to high-quality ingredients, custom formulations, and finished products across multiple industries.
Professional Manufacturer: Xi'an Huilin Bio-tech Co., Ltd. is a high-tech biotechnology company specializing in the production, R&D, and export of natural botanical extracts.
Quality Assurance: Every batch undergoes rigorous testing for capsaicin content (HPLC), heavy metals (ICP-MS), and microbiological purity to ensure consistent quality and safety.
Flexible Specifications: We offer a wide range of specifications from 1% to 98% capsaicin content to meet diverse application requirements.
Customization Capabilities: We offer flexible packaging options and custom formulations to meet diverse customer requirements.
Supply Chain Reliability: With established supply chains and robust production capacity, we ensure timely delivery and stable supply for bulk orders.
Technical Support: Our experienced R&D team provides formulation guidance and technical support throughout your product development process.
Global Compliance: Products are manufactured in compliance with international quality standards and regulatory requirements.
For inquiries, quotations, or sample requests, please contact: sales@huilinbio-tech.com
References
1. Comparative proteomic analysis of the sun- and freeze-dried earthworm Eisenia fetida with differentially thrombolytic activities. Journal of Proteomics. 2013.
(Freeze-dried earthworms showed dramatically higher fibrinolytic and thrombolytic activities than sun-dried earthworms. Five differential proteins identified as fibrinolytic proteases (lumbrokinases).)
2. Preparation method and application of earthworm freeze-dried powder. Patent CN115736251A. 2022.
(Earthworm protein can inhibit ACE activity and reduce blood pressure. Freeze-drying avoids color change, taste change, and nutrient loss caused by traditional dehydration.)
3. A novel fibrinolytic enzyme extracted from the earthworm, Lumbricus rubellus. PubMed.
(A strong fibrinolytic enzyme was readily obtained in saline extracts of the earthworm. Named collectively as Lumbrokinase.)
4. Pheretima: A system review of zoology, traditional applications, processing technology, chemical composition, pharmacologic activities, quality control and toxicity. PubMed. 2025.
(For thousands of years, Pheretima has been utilized for renal yang deficiency, weakness of tendons and bones, benign tumors, ulcerative diseases, and cardiovascular and cerebrovascular diseases.)
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