Introduction
Poecilobdella Manillensis Freeze-Dried Powder is a premium-grade raw material derived from the whole body of the Philippine leech (Poecilobdella manillensis, also known as the golden-edged leech), a species of medicinal leech widely used in traditional medicine and modern nutraceutical applications. The product is processed using advanced freeze-drying (lyophilization) technology that preserves the natural bioactive compounds, particularly hirudin – the most potent natural thrombin inhibitor known to science.
While freeze-dried powder is our most versatile and widely used form, we also offer freeze-dried whole leech strips for traditional Chinese medicine decoction piece applications requiring visual identification, and live leeches for medical hirudotherapy and fresh applications. Our complete product line allows us to serve customers across the nutraceutical, pharmaceutical, cosmetic, and traditional medicine sectors with the form that best suits their specific needs.
Hirudin is a naturally occurring peptide found in leech saliva that specifically binds to and inactivates thrombin, the key enzyme in the blood coagulation cascade. In addition to hirudin, leeches secrete more than 20 identified bioactive substances, including antistasin, eglins, guamerin, saratin, bdellins, and various enzyme inhibitors, which collectively exhibit analgesic, anti-inflammatory, platelet inhibitory, anticoagulant, and thrombin regulatory functions. These compounds work synergistically to support cardiovascular health, improve blood circulation, and promote overall wellness.
Our product is manufactured from legally farmed Poecilobdella manillensis raised under controlled conditions with proper veterinary oversight. The freeze-drying process occurs at low temperatures, which effectively preserves heat-sensitive bioactive compounds, growth factors, and enzymes that would otherwise be degraded by traditional heat-based drying methods. The result is a consistently pure, highly active powder with stable hirudin activity levels ranging from 200 to 1,200 ATU, meeting the quality standards of the Chinese Pharmacopoeia. All products are free from pesticide residues and heavy metals within safe limits.
Available Product Forms – Comparison
To help you select the right form for your application, we offer three distinct product forms:
| Feature | Freeze-Dried Powder | Freeze-Dried Whole Strips | Live Leeches |
|---|---|---|---|
| Appearance | Brownish to dark brown fine powder | Whole leech bodies, natural shape retained, brownish to dark brown | Live, active, with golden stripes on the back |
| Processing | Vacuum freeze-drying + pulverization | Vacuum freeze-drying only (no pulverization) | Live, unprocessed |
| Hirudin Activity | 200 – 1,200 ATU (standardized) | 200 – 1,200 ATU (standardized) | Variable (depends on health and collection timing) |
| Shelf Life | 24 months | 24 months | Limited (days to weeks) |
| Storage | Cool, dry, sealed | Cool, dry, sealed | Specialized live culture conditions |
| Best For | Nutraceuticals, cosmetics, capsules, tablets, functional foods | TCM decoction pieces, clinical prescriptions, herbal pharmacies | Medical hirudotherapy (hospitals, clinics), fresh applications |
| Key Advantage | Most versatile, easiest to formulate | Ideal for traditional applications requiring whole-body identification | Live enzymes and bioactive factors at maximum potency |
Key Features & Advantages
- Potent Natural Thrombin Inhibitor – Contains hirudin, the most potent natural thrombin inhibitor known, which specifically binds to and inactivates thrombin
- Multiple Bioactive Compounds – Rich in over 20 bioactive substances, including hirudin, antistasin, eglins, guamerin, saratin, and bdellins, with synergistic effects
- Supports Cardiovascular Health – Helps maintain healthy blood circulation, supports normal blood lipid levels, and promotes cardiovascular wellness
- Anticoagulant & Antithrombotic Properties – Exhibits strong antithrombin activity in vitro and supports healthy blood viscosity
- Anti-Inflammatory & Analgesic Effects – Contains bioactive compounds with anti-inflammatory and pain-relieving properties
- High & Stable Activity – Hirudin activity levels from 200 to 1,200 ATU with consistent batch-to-batch performance
- Freeze-Dried Processing – Advanced lyophilization preserves heat-sensitive bioactive compounds and enzymes
- 100% Pure – No additives, fillers, or preservatives
- Pesticide-Free – No agricultural residues
- Heavy Metals – Within safe limits, compliant with international standards
-
Multiple Forms Available – Powder, whole strips, and live leeches to suit different applications
Technical Specifications(powder)
| Parameter | Specification |
|---|---|
| Product Name | Poecilobdella Manillensis Freeze-Dried Powder |
| Species | Poecilobdella manillensis (Philippine Leech) |
| Appearance | Brownish to dark brown fine powder |
| Hirudin Activity | 200 – 1,200 ATU (customizable) |
| Active Compounds | Hirudin, antistasin, eglins, guamerin, saratin, bdellins, and other bioactive peptides |
| Particle Size | 80–100 mesh (customizable) |
| Moisture Content | ≤5% |
| Purity | 100% pure, no additives |
| Pesticide Residues | None detected |
| Heavy Metals | Within safe limits |
| Total Plate Count | Compliant with food/pharmaceutical standards |
| E. coli | Negative |
| Salmonella | Negative |
| Storage | Cool, dry, dark place; sealed container |
| Shelf Life | 24 months |
Specifications are for reference. Please request the current COA for batch-specific data.
Key Health Benefits
Poecilobdella Manillensis Freeze-Dried Powder is a scientifically studied natural ingredient with benefits supported by traditional use and modern research. Here are the key highlights in simple terms:
1. Supports Healthy Blood Circulation
Hirudin, the main active compound in leech powder, is a natural blood thinner that helps maintain healthy blood flow. It works by blocking thrombin – a key protein involved in blood clotting – helping to keep blood vessels clear and circulation smooth.
2. Promotes Cardiovascular Wellness
The combination of hirudin and other bioactive compounds in leech powder helps support normal blood lipid levels, maintain healthy blood pressure, and promote overall heart health.
3. Helps Maintain Healthy Blood Viscosity
Research has shown that leech freeze-dried powder exhibits strong antithrombin activity, which helps maintain healthy blood viscosity and supports normal blood flow.
4. Anti-Inflammatory Support
Leeches secrete multiple bioactive substances with anti-inflammatory properties that may help support the body's natural inflammatory response.
5. Traditional Use for Circulation Support
With over 2,000 years of recorded use in traditional medicine, leech products have been traditionally used to support blood circulation, promote recovery from injury, and maintain overall wellness.
Applications
- Health Supplements & Nutraceuticals – Capsules, tablets, and powders for cardiovascular health, circulation support, and overall wellness
- Functional Foods – Fortified foods and beverages targeting cardiovascular wellness
- Traditional Medicine Formulations – Traditional Chinese medicine preparations for blood circulation and stasis resolution
- Pharmaceutical Intermediates – Raw material for pharmaceutical products targeting thromboembolic conditions
- Cosmetics & Personal Care – Skincare products for improving skin microcirculation, reducing redness, and promoting a healthy complexion
- Animal Health – Feed additives for livestock and aquaculture health
- Research & Development – Raw material for bioactive compound research and product development
Frequently Asked Questions (FAQ)
Q: Are the leeches farmed or wild-caught?
A: All our leech products are sourced from legally farmed Poecilobdella manillensis raised on certified farms under controlled conditions with proper veterinary oversight. We do not use wild-caught leeches. Full documentation and traceability records are available.
Q: What is hirudin and why is it important?
A: Hirudin is a naturally occurring peptide found in leech saliva and is the most potent natural thrombin inhibitor known to science. It works by specifically binding to and inactivating thrombin, the key enzyme in the blood coagulation cascade. This makes it valuable for supporting healthy blood circulation and cardiovascular wellness.
Q: What does "ATU" mean?
A: ATU stands for Anti-Thrombin Unit – the standard unit used to measure hirudin activity. One ATU is defined as the amount of hirudin that neutralizes one NIH unit of thrombin. Our products are available with hirudin activity levels ranging from 200 to 1,200 ATU.
Q: Is this product suitable for use in food products?
A: Yes. Our Poecilobdella Manillensis Freeze-Dried Powder is produced to food-grade standards and can be used as a raw material in health supplements, functional foods, and traditional medicine formulations.
Q: What is the difference between freeze-dried powder and traditionally dried products?
A: Freeze-drying (lyophilization) removes moisture through sublimation at low temperatures, while traditional drying uses heat. Freeze-drying better preserves heat-sensitive bioactive compounds like hirudin, resulting in higher activity levels and better preservation of naturally occurring bioactive substances.
Q: Can this product be used in cosmetic applications?
A: Yes. Hirudin and other leech-derived bioactive compounds are increasingly used in cosmetic applications for their ability to improve skin microcirculation, promote a healthy complexion, and support skin renewal.
Q: What is the shelf life, and how should the powder be stored?
A: The product has a shelf life of 24 months from the date of manufacture when stored under recommended conditions. Store in a cool, dry place, protected from light and moisture. Keep containers tightly sealed when not in use.
Q: What traditional uses does this product have?
A: Leech products have been used in traditional medicine for over 2,000 years, primarily for promoting blood circulation, resolving blood stasis, and supporting recovery from injury. They are traditionally used for conditions related to poor circulation and blood stagnation.
Q: What is the difference between freeze-dried powder and freeze-dried strips?
A: Freeze-dried powder is a fine powder suitable for capsules, tablets, functional foods, and cosmetics. Freeze-dried strips retain the whole-body leech form and are primarily used in traditional Chinese medicine as decoction pieces for clinical prescriptions. Both share the same bioactive profile and quality standards but serve different end-use applications.
Why Choose Huilin Bio-Tech?
Your Professional Manufacturing & Sourcing Partner
We are more than a supplier - we are a comprehensive supply chain partner dedicated to high-quality ingredients, custom formulations, and finished products across multiple industries.
Professional Manufacturer: Xi'an Huilin Bio-tech Co., Ltd. is a high-tech biotechnology company specializing in the production, R&D, and export of natural botanical extracts.
Quality Assurance: Every batch undergoes rigorous testing for capsaicin content (HPLC), heavy metals (ICP-MS), and microbiological purity to ensure consistent quality and safety.
Flexible Specifications: We offer a wide range of specifications from 1% to 98% capsaicin content to meet diverse application requirements.
Customization Capabilities: We offer flexible packaging options and custom formulations to meet diverse customer requirements.
Supply Chain Reliability: With established supply chains and robust production capacity, we ensure timely delivery and stable supply for bulk orders.
Technical Support: Our experienced R&D team provides formulation guidance and technical support throughout your product development process.
Global Compliance: Products are manufactured in compliance with international quality standards and regulatory requirements.
For inquiries, quotations, or sample requests, please contact: sales@huilinbio-tech.com
1. Medicinal leech therapy-an overall perspective. PubMed. 2017.
(Leeches secrete more than 20 identified bioactive substances including antistasin, eglins, guamerin, hirudin, saratin, bdellins; have analgesic, anti-inflammatory, platelet inhibitory, anticoagulant, and thrombin regulatory functions.)
2. The return of the leech. PubMed.
(Hirudin may lead to wider therapeutic applications in the prevention and treatment of thromboembolic disease.)
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