Name: China High Quality Rutin Powder Manufacturers Suppliers - Factory Direct Wholesale - HUILIN BIO
Brand: Huilin
SKU: 302565705

Rutin supplied by Huilin

Rutin is a naturally occurring flavonoid glycoside found in buckwheat, citrus fruits, apples, asparagus, and green tea. Historically called "Vitamin P" (for permeability), it is well known for supporting blood vessel integrity and microcirculation.

The primary commercial source for high‑purity rutin powder is Sophora japonica L. (Japanese pagoda tree) flower buds, which contain up to 20–30% rutin by dry weight. China is the world's dominant supplier, with major extraction facilities in Shandong, Anhui, Henan, and Shaanxi provinces. Xi'an, the capital of Shaanxi, is a strategic hub for the natural plant extract industry, and our manufacturing facilities are centrally located here, ensuring direct access to high‑quality Sophora japonica bud raw material and efficient quality control.

Rutin functions as a powerful antioxidant, scavenging free radicals and protecting cells from oxidative stress. It is safe, well‑tolerated, and widely used in supplements, pharmaceuticals (as a precursor to troxerutin), functional foods, and cosmetics. It meets USP/NF, EP, DAB, and CP standards and is listed in the FDA's EAFUS database ^[1].

Certificate of Analysis (COA) – Typical Specification

Item	Specification	Result	Method
Identification (IR)	Conforms to standard	Conforms	USP <197K>
Appearance	Yellow to yellowish‑green powder	Conforms	Visual
Assay (HPLC)	95.0% – 101.0%	95.14%	USP
Quercetin (Impurity)	≤2.0%	<2.0%	HPLC
Isoquercitroside (Impurity)	≤2.0%	<2.0%	HPLC
Kaempferol 3‑rutinoside	≤2.0%	<2.0%	HPLC
Total Impurities	≤4.0%	Conforms	HPLC
Loss on Drying	5.5% – 9.0%	8.11%	USP <921>
Residue on Ignition	≤0.1%	0.12%	USP <281>
Heavy Metals (Total)	≤10 ppm	Conforms	USP <231>
Lead (Pb)	≤1–3 ppm	Conforms	USP <211>
Total Plate Count	≤1,000 CFU/g	Conforms	USP <2021>
E. coli / Salmonella	Negative	Negative	USP <2022>
Particle Size	≥95% passes 80 mesh	99%	CP2020

Briefly describe the production process

Our rutin powder is produced from premium Sophora japonica flower buds. The dried buds are milled and extracted using water or aqueous ethanol. The extract is concentrated, and the pH is adjusted to precipitate rutin selectively. The crude product is purified by recrystallization to achieve ≥95% or ≥98% purity. The purified crystalline rutin is dried, milled, and sieved to a fine powder (≥95% passes 80 mesh). Each batch is tested for assay, related substances, heavy metals, loss on drying, residue on ignition, and microbial limits before release. Packaging is moisture‑barrier and light‑protective.

rutin benefits

1. Powerful Antioxidant Activity
Rutin efficiently scavenges free radicals, reducing oxidative stress and protecting cell membranes, proteins, and DNA^[1].

2. Supports Cardiovascular and Vascular Health
Rutin strengthens capillaries, reduces permeability, and improves microcirculation. A 2024 RCT showed that a rutin derivative (monoglucosyl rutin) reduced LDL‑C by 5.0% in healthy adults with mild hypercholesterolemia^[3].

3. Supports Healthy Inflammatory Responses and Skin Health
Rutin possesses anti‑inflammatory properties, supporting skin barrier function, soothing irritation, and protecting against UV‑induced damage.

4. Contributes to Metabolic and Cellular Health
Preclinical studies suggest rutin helps maintain healthy glucose and lipid metabolism and may offer hepatoprotective effects.

5. Safe for Long‑Term Use
Rutin is well tolerated. In one study, 84% of participants reported no side effects, and 97% expressed willingness to continue long‑term use^[3].

Applications of Rutoside

1. Dietary Supplements

Capsules, tablets, softgels for antioxidant, vascular health, and anti‑inflammatory formulas (50–500 mg per serving).

2. Pharmaceutical API

Precursor for troxerutin and quercetin production; NF‑grade (≥95%) and ≥98% pharmaceutical grade available.

3. Functional Foods & Beverages

Natural antioxidant, preservative, and UV‑absorbent in beverages, baked goods, and dairy.

4. Cosmetics & Personal Care

Anti‑aging, anti‑sensitivity, and sunscreen products; hair care formulations.

5. Animal Nutrition

Antioxidant support for companion animals, equine supplements, and livestock feed.

uses Of Rutin

Frequently Asked Questions (FAQ)

Q: What is the difference between NF grade rutin and pharmaceutical grade rutin?

A: NF grade (≥95% purity) is the standard for dietary supplements. Pharmaceutical grade (≥98% purity) has stricter impurity controls (quercetin, isoquercitroside, etc.) and meets full USP/EP/CP monographs, suitable for API use.

Q: What are the most critical QC parameters for Rutoside powder?

A: Assay (HPLC 95–101%), related substances (quercetin ≤2%, isoquercitroside ≤2%, kaempferol‑3‑rutinoside ≤2%, total impurities ≤4%), loss on drying (5.5–9.0%), heavy metals (total ≤10 ppm), and microbial limits.

Q: How stable is rutin, and how should it be stored?

A: Rutin is sensitive to light and moisture. Store in tightly sealed, light‑protective, moisture‑resistant containers, cool and dry (<30°C). Refrigeration (2–8°C) is preferred for long‑term color stability and potency retention (24–36 months).

Q: Why are the impurity limits for quercetin and related flavonoids important?

A: Quercetin has a different biological profile and may cause concerns at high levels. USP/NF limits ensure product safety and regulatory compliance.

Q: What packaging options are available?

A: Aluminum foil bags (1–5 kg), sealed plastic drums (10–25 kg), fiber drums (25–50 kg), and customized packaging. All are light‑protective and moisture‑resistant.

Q: Do you offer custom formulation or private‑label finished products?

A: Yes. Custom blending (rutin + diosmin + hesperidin, etc.), private‑label tablets, capsules, powder sticks, and gummies. Contact the technical team for details.

Q: Is rutin suitable for use in beverages and functional foods?

A: Unmodified rutin has poor water solubility, but micronized forms and novel rutin‑casein composites (bioaccessibility 45–63%) are available. We offer micronized rutin for improved dispersion.

Q: Why is Sophora japonica the preferred source for rutin?

A: It contains 20–30% rutin (vs. <2% in other plants), making extraction economically viable and purification simpler.

Q: Why is Xi'an a strategic base for rutin supply?

A: Xi'an is a hub of China's plant extract industry, located in Shaanxi province - a primary Sophora japonica growing region. This ensures a stable raw material supply, direct sourcing, and competitive pricing.

Why Choose Us?

Your Professional Manufacturing & Sourcing Partner

We are more than a supplier - we are a comprehensive supply chain partner dedicated to high-quality ingredients, custom formulations, and finished products across multiple industries.

Professional Expertise

With years of experience in plant extracts, food additives, cosmetic raw materials, and nutritional ingredients, our team brings deep technical knowledge and market insight to every partnership.

Diverse Product Range

We offer a broad range of products, including food additives, plant extracts, fruit & vegetable powders, cosmetic actives, and functional food ingredients.

One-Stop Shop

Raw Materials: High-purity ingredients for food, beverage, supplement, and cosmetic applications.

Finished Products: In-house manufacturing of capsules, soft gels, gummies, liquid drops, and blended powders.

OEM/ODM/OBM Services

Label Design & Packaging: Custom branding tailored to your target market.

Formulation & R&D: Expert support to develop custom blends, proprietary formulas, and innovative products.

Global Logistics: Reliable shipping, documentation, and customs clearance support.

Quality Assurance

Strict adherence to GMP standards and full regulatory transparency. We stay current with global requirements, including FDA GRAS, EFSA, and other regional regulations, to ensure your products meet the highest safety and compliance standards.