What is Tesamorelin
Tesamorelin (CAS 218949-48-5) is a synthetic growth hormone-releasing hormone (GHRH) analog composed of 44 amino acids[1]. It was specifically engineered to mimic the activity of endogenous GHRH, thereby stimulating the synthesis and secretion of growth hormone (GH) from the anterior pituitary gland[2]. By binding to GHRH receptors, tesamorelin promotes pulsatile GH release, which in turn upregulates insulin-like growth factor 1 (IGF-1) production, playing a critical role in metabolic regulation and anabolic processes[2].
This peptide has been the subject of extensive research, particularly in the context of metabolic disorders and body composition modulation. Studies have explored its potential benefits in conditions such as HIV-associated lipodystrophy, obesity, and age-related GH decline, focusing on its ability to reduce visceral adipose tissue and improve lipid profiles without significantly impacting glucose metabolism[3]. Its targeted action offers a research advantage over direct GH administration by supporting more physiological hormone secretion patterns[2].
Ongoing investigations continue to elucidate the molecular pathways and long-term effects of tesamorelin, reinforcing its importance as a tool for understanding GH physiology and its therapeutic potential in endocrinology and metabolic research[3].
Physicochemical Properties
| Property | Description |
|---|---|
| Product Name | Tesamorelin |
| Product Appearance | White lyophilized powder |
| Molecular Formula | C₂₂₁H₃₆₆N₇₂O₆₇S |
| Molecular Weight | 5135.9 g/mol |
| CAS NO | 218949-48-5 |
| Purity (HPLC) | >98.0% |
| Shelf Life | 36 months under recommended storage |
| Solubility | Soluble in sterile water or bacteriostatic water |
| Storage | Store at -20°C, protect from light and moisture |
Characteristics of Tesamorelin
- High Purity: >98.0% verified by HPLC and mass spectrometry
- Stability: Maintains integrity under recommended storage conditions
- Synthetic Origin: Ensures batch-to-batch consistency and minimal biological contaminants
- Research Grade: Suitable for in vitro and animal model studies
Potential Benefits (Research Insights)
Note: The following information is derived from published preclinical studies and is provided for research purposes only. This product is not intended for human or diagnostic use.
Research studies have identified several areas of scientific interest for Tesamorelin [2,3]:
- Endocrine System Research: Investigation of growth hormone release mechanisms and regulation
- Metabolic Studies: Exploration of lipid metabolism and body composition parameters
- Receptor Interaction Studies: Analysis of GHRH receptor binding and signaling pathways
- Age-Related Research: Examination of endocrine function in experimental models
Uses of Tesamorelin
Tesamorelin supports diverse scientific investigations across multiple disciplines [1,3,5]:
- Academic Research Programs: Employed in physiological studies focusing on growth hormone regulation mechanisms and their broader implications for endocrine system function [3].
- Pharmaceutical Development: Serves as a reference compound during early-stage research and development of metabolic disorder therapeutics, particularly those involving growth hormone pathways [5].
- Biochemical Mechanism Studies: Utilized for examining peptide-receptor interaction dynamics and subsequent signal transduction pathways in controlled laboratory settings [1].
- Metabolic Research Initiatives: Applied in experimental models investigating body composition regulation mechanisms and energy metabolism processes [3].
- Endocrinology Research: Facilitates the study of pituitary gland function and complex hormone regulation networks in physiological research [5].
OME service
We provide customized services to meet the different needs of customers:
◇ Product customization services of different specifications.
◇ Provide powder processing services. Such as powder canned capsules, powder compressed tablets, and so on.
◇ Customized service of the outer packaging, such as ziplock bag packaging, and bottled packaging. Carton packaging, etc., and special packaging require customers to provide design materials.
Packaging & Shipping
Mode of Transport：
- Express delivery: door-to-door service
- Air transport: fast
- Sea transportation: low transportation cost
Certification
Frequently Asked Questions (FAQ)
Q: Is Tesamorelin approved for human use?
A: While pharmaceutical formulations exist, this product is strictly for research purposes in laboratory settings only.
Q: What documentation is provided with the product?
A: All products include a Certificate of Analysis verifying purity and quality specifications.
Q: What is the typical shipping time for international orders?
A: Most international research orders are processed within 7-15 business days with appropriate cold chain packaging.
Why Choose Us?
✔ We can provide you with customized services, such as OEM, and ODM services.
✔ We guarantee that if there is a quality problem, you can return or refund within one month.
✔ We have professional product quotations and product catalogs.
✔ Our products have a certificate of inspection certified by an international company
✔ When we have sufficient inventory, we can quickly deliver goods to customers.
✔ We have a professional team and rich experience
References
[1] National Center for Biotechnology Information. PubChem Compound Summary for CID 16165308
[2] Smit, P., & van der Lely, A. J. (2010). Expert Opinion on Biological Therapy, 10(12), 1701-1708
[3] Stanley, T. L., & Grinspoon, S. K. (2012). Nature Reviews Endocrinology, 8(4), 243-253
[4] Clinical studies on metabolic effects of growth hormone modulation
[5] Research on GHRH analog applications in endocrine disorders
Disclaimer
This product is intended solely for research purposes in controlled laboratory environments. It is not intended for diagnostic, therapeutic, or human use. Purchasers must ensure compliance with all applicable laws and regulations governing the possession and use of research compounds. Xi'an Huilin Biological Technology Co., Ltd. assumes no liability for misuse or unauthorized handling of this material.
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