Palmitoyl Pentapeptide-4 Powder | Clinically Proven Anti-Wrinkle Peptide | B2B Ingredient
Source high-purity Palmitoyl Pentapeptide-4. This gold-standard anti-aging peptide delivers identical efficacy to Matrixyl™ in stimulating collagen & reducing wrinkles. For Global Brands.
Introduction: The Gold-Standard in Anti-Aging Peptides
Palmitoyl Pentapeptide-4 Powder is the scientifically recognized name for the pioneering anti-aging peptide that set the global standard for topical, signal-mediated skin rejuvenation. As a premier B2B supplier of proven active ingredients, we provide formulators with high-purity Palmitoyl Pentapeptide-4 that delivers identical efficacy and mechanism of action to the originally trademarked Matrixyl™ ingredient. This clinically-validated molecule empowers the skin's natural repair processes, delivering visibly smoother, firmer, and younger-looking skin.
Physicochemical Properties Table of Matrixyl Powder
| Property | Specification |
|---|---|
| Product Name | Palmitoyl Pentapeptide-4 |
| CAS Number | 214047-00-4 |
| Molecular Formula | C39H75N7O10 |
| Molecular Weight | 802.054 g/mol |
| Purity | ≥ 98% (by HPLC) |
| Appearance | White to off-white fine powder |
| Solubility | Soluble in water, Glycerin, Propylene Glycol |
| Shelf Life | 24 months under proper storage conditions. |
Mechanism of Action of Palmitoyl Pentapeptide-4
Palmitoyl Pentapeptide-4 is a master signal peptide. Its innovative design combines the bioactive fragment of Procollagen I (KTTKS) with a palmitoyl fatty acid chain.
- Enhanced Penetration: The palmitoyl chain acts as a natural shuttle, facilitating optimal dermal delivery of the peptide sequence.
- Fibroblast Communication: Once delivered, the peptide sequence acts as a messenger, binding to specific receptors on fibroblasts.
- Boosted ECM Production: This binding triggers a natural response, stimulating fibroblasts to ramp up production of key structural components of the Extracellular Matrix (ECM), including Collagen I, III, IV, and Fibronectin [1].
- Structural Repair: By replenishing the skin's foundational support structure, Palmitoyl Pentapeptide-4 effectively combats the visible signs of aging caused by collagen degradation.
Key Benefits & Clinical Evidence of Matrixyl
Formulate with the confidence that comes from the extensive clinical legacy of Palmitoyl Pentapeptide-4.
- Clinically Proven Wrinkle Reduction: The foundational double-blind, placebo-controlled clinical study that established the efficacy of this molecule demonstrated that Palmitoyl Pentapeptide-4 significantly reduces wrinkle depth, volume, and skin roughness compared to placebo, with performance comparable to Retinol over a 4-month period [1]. This is the same study that validated the ingredient originally marketed as Matrixyl™.
- Stimulates Collagen & Firmness: Directly addresses sagging skin by promoting the synthesis of new collagen, leading to a measurable improvement in skin firmness and elasticity.
- Reduces Fine Lines: Effectively smoothens the appearance of fine lines, particularly around the eyes and forehead.
- Improves Skin Texture & Hydration: A reinforced ECM supports better hydration and creates a smoother, more refined skin surface.
Application of KTTKS Powder
Integrate the proven power of Palmitoyl Pentapeptide-4 Powder into your next generation of skincare heroes.
Recommended Concentration: 3% - 5% in the final product.
Ideal For:
Anti-Wrinkle Serums & Concentrates
Firming & Lifting Creams
Eye Contour Treatments
Day/Night Moisturizers
Formulation Tip: This peptide is highly soluble and stable. Incorporate it into the water phase of your emulsion at temperatures below 40°C to preserve its activity.
Frequently Asked Questions (FAQ)
Q: What is the relationship between Palmitoyl Pentapeptide-4 and Matrixyl™?
A: Palmitoyl Pentapeptide-4 is the universal scientific name for the active molecule. Matrixyl™ is a specific brand name for this ingredient. Our Palmitoyl Pentapeptide-4 is the same core molecule, manufactured to the highest standards of purity and efficacy, ensuring you receive an ingredient with identical performance and clinical backing.
Q: How does Palmitoyl Pentapeptide-4 differ from other anti-aging peptides like Hexapeptide-9 (KTTKS)?
A: Palmitoyl Pentapeptide-4 is a lipopeptide (KTTKS + Palmitoyl) designed for optimal skin penetration and targeted fibroblast signaling. Hexapeptide-9 (KTTKS) is the pure peptide fragment without the lipid carrier. The palmitoyl chain in Palmitoyl Pentapeptide-4 is crucial for its enhanced bioavailability and efficacy in topical formulations.
Q: What is the recommended dosage?
A: For clinically-substantiated results, a concentration of 3% to 5% Palmitoyl Pentapeptide-4 in the final formulation is recommended.
Q: Do you provide documentation for global compliance?
A: Absolutely. We provide a comprehensive Certificate of Analysis (COA) with every batch, along with a detailed Product Specification Sheet. These documents are essential for your compliance files in major markets like the EU, USA, and Asia.
Contact Us
Access the gold-standard anti-aging efficacy of Palmitoyl Pentapeptide-4 directly from a reliable B2B source. Build your brand on science, not just branding.
Contact Us Today to request a technical data sheet, current pricing, and a sample. E-mail: ella.zhang@huilinbio-tech.com.
References
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