Acetyl Tetrapeptide-5 Powder | Anti-Aging & Under-Eye Care Peptide | Cosmetic Ingredient
Source high-purity Acetyl Tetrapeptide-5 for cosmetic formulations. Targets under-eye bags, dark circles & fine lines by improving skin elasticity & microcirculation. B2B Supplier.
Introduction: A Targeted Solution for Delicate Skin Areas
Acetyl Tetrapeptide-5 Powder is a sophisticated, synthetic peptide engineered to address multiple signs of aging, particularly in the fragile periorbital area (around the eyes). As a specialized B2B supplier of cosmetic active ingredients, we provide formulators with a high-purity, multi-functional ingredient that helps rejuvenate the appearance of tired-looking skin, resulting in a smoother, firmer, and more radiant complexion.

Physicochemical Properties Table of Matrixyl Powder
| Property | Specification |
|---|---|
| Product Name | Acetyl Tetrapeptide-5 |
| CAS Number | 820959-17-9 (Note: Shared with related tetrapeptides) |
| Molecular Formula | C20H28N8O7 |
| Molecular Weight | 492.486 g/mol |
| Purity | ≥ 98% (by HPLC) |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in water, Glycerin |
| Shelf Life | 24 months under proper storage conditions. |
Mechanism of Action: Multi-Targeted Rejuvenation
Acetyl Tetrapeptide-5 employs a dual-mechanism approach to combat aging signs, focusing on both structural support and microcirculation:
- Stimulates Elastin Production: It promotes the synthesis and organization of elastin fibers in the skin. Elastin is the protein responsible for skin's snap-back elasticity and resilience. By reinforcing the elastic network, the peptide helps to firm sagging skin and reduce the appearance of fine lines caused by loss of elasticity [1].
- Improves Microcirculation: It helps to strengthen the walls of peripheral blood capillaries. This action reduces vascular leakage and the subsequent deposition of blood-derived pigments (like hemosiderin), which contribute to the appearance of dark circles under the eyes. This also aids in reducing fluid accumulation that leads to puffiness.

Key Benefits of Acetyl Tetrapeptide-5
Formulate with confidence using an ingredient that targets the most visible signs of aging in high-demand product categories.

1. Firms and Tightens Skin: By boosting the skin's own elastin, it helps improve firmness and resilience, counteracting sagging, particularly on the cheeks and under the eyes.
2. Reduces the Appearance of Under-Eye Bags and Puffiness: The combination of improved structural support and enhanced microcirculation helps to deflate the look of under-eye bags.
3. Lightens Dark Circles: Targets the bluish-purple discoloration under the eyes by minimizing capillary leakage and pigment deposition.
4. Smooths Fine Lines: A more robust elastic matrix helps to smooth out fine lines and wrinkles, especially those caused by loss of skin elasticity.
Application & Formulation Guidance

Incorporate Acetyl Tetrapeptide-5 Powder into a wide range of targeted skincare solutions.
Recommended Concentration: 2% - 5% in the final product.
Ideal For:
Under-Eye & Contour Creams
Firming & Lifting Serums
Anti-Aging Moisturizers
Neck Creams
Formulation Tip: This water-soluble peptide is ideal for the water phase of emulsions or aqueous gel serums. Incorporate at low temperatures (<40°C) to maintain stability and activity.
Frequently Asked Questions (FAQ)
Q: What is the main difference between Acetyl Tetrapeptide-5 and other anti-aging peptides?
A: Acetyl Tetrapeptide-5 is distinguished by its dual focus on elastin synthesis and microcirculation. While many peptides target collagen or muscle contractions, this peptide specifically helps restore skin elasticity and address under-eye concerns like puffiness and dark circles from a vascular perspective.
Q: Is this peptide safe for use around the eyes?
A: Yes, Acetyl Tetrapeptide-5 is specifically designed for topical use, including the delicate eye contour area. It is considered a safe and well-tolerated cosmetic active ingredient.
Q: What is the recommended dosage in a formulation?
A: A concentration of 2% to 5% is recommended for optimal efficacy based on available efficacy data.
Q: Do you provide a Certificate of Analysis (COA)?
A: Absolutely. Every batch of our Acetyl Tetrapeptide-5 Powder comes with a comprehensive COA, verifying its purity, identity, and quality through HPLC and other relevant analyses.
Contact Us
Elevate your anti-aging and eye care formulations with the multi-targeted efficacy of Acetyl Tetrapeptide-5. Partner with us for a reliable supply of high-purity peptides.
Contact Us Today to request a technical data sheet, current pricing, and a sample. E-mail: ella.zhang@huilinbio-tech.com.
References
[1] (The specific clinical data for Acetyl Tetrapeptide-5 is often proprietary. The described mechanisms are consistent with supplier claims and established dermatological science.)
The mechanism of action and efficacy are supported by supplier-provided in vitro and clinical data on file, demonstrating its role in promoting elastin production and improving the appearance of the under-eye area.
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