Products Description
AHK Tripeptide-3 Powder - The Cellular Renewal & Anti-Aging Peptide
AHK Tripeptide-3, also known by its chemical name L-Alanyl-L-histidyl-L-lysine, is a renowned cosmetic peptide celebrated for its powerful anti-aging and skin regeneration properties. This tripeptide, composed of the amino acids Alanine, Histidine, and Lysine, is a key player in cellular communication, helping to restore a more youthful and vibrant complexion. It is widely recognized for its role in promoting wound healing, enhancing skin firmness, and supporting the health of the skin's extracellular matrix, making it a cornerstone ingredient in high-performance skincare products [1].
Biophysical & Chemical Parameters Table
The following table summarizes the key specifications of AHK Tripeptide-3 Powder:
| Parameter | Specification |
|---|---|
| Product Name | AHK Tripeptide-3 Powder |
| Other Name | H-Ala-His-Lys-OH, AHK |
| Chemical Name | L-Alanyl-L-histidyl-L-lysine |
| CAS Number | 126828-32-8 |
| Molecular Formula | C15H26N6O4 |
| Molecular Weight | 354.405 g/mol |
| Purity | ≥ 99% |
| Appearance | White to off-white free-flowing powder |
| Solubility | Soluble in water |
Mechanism of Action: How AHK Works
The efficacy of AHK Tripeptide-3 is primarily attributed to its ability to function as a copper-binding peptide and a cell-communicating ingredient.
- Copper Binding: The structure of AHK Tripeptide-3 has a high affinity for copper ions (Cu²⁺), naturally forming a complex in the skin. Copper is an essential co-factor for numerous enzymes critical for skin health [2].
- Cellular Signaling: This peptide acts as a signal messenger, influencing cellular behavior. It is known to promote the production of key structural components of the skin, such as collagen and glycosaminoglycans, by activating relevant pathways in fibroblasts, the skin's building cells [3]. This process helps to counteract the natural decline of these substances that occurs with aging.
Key Benefits of AHK Powder
Formulate with AHK Tripeptide-3 to deliver these proven skin benefits:
- Stimulates Skin Regeneration: Promotes cellular turnover and tissue repair, aiding in the improvement of skin texture and resilience.
- Enhances Collagen & Elastin Production: Helps to restore the skin's structural foundation, leading to improved firmness and reduced sagging [3].
- Powerful Anti-Aging Effects: Visibly reduces the appearance of fine lines and wrinkles by rejuvenating the skin from within.
- Improves Skin Barrier Function: Supports a healthier skin barrier, which can enhance hydration and protect against environmental stressors.
- Antioxidant & Protective Properties: The copper-binding activity provides antioxidant benefits, helping to neutralize free radicals and support overall skin health.
Applications in Cosmetic Formulations
AHK Tripeptide-3 is a versatile and water-soluble ingredient, making it ideal for a wide range of cosmetic and personal care products.
Recommended Usage Level: 1% - 5% in the final product.
Ideal for:
Anti-Aging Serums & Creams: As a core active for reducing wrinkles and improving skin density.
Firming & Lifting Treatments: Specifically designed for the face, neck, and décolletage areas.
Post-Procedure Skincare: To support skin healing and regeneration after cosmetic treatments (where legally permitted).
Advanced Night Repair Formulations: To leverage the skin's natural overnight regenerative cycle.
Frequently Asked Questions (FAQ)
Q: Is AHK Tripeptide-3 safe for cosmetic use?
A: Yes. AHK Tripeptide-3 is considered safe for topical application in cosmetics. It is compliant with international cosmetic ingredient regulations. As with all ingredients, it should be used at recommended concentrations.
Q: How is AHK Tripeptide-3 different from other anti-aging peptides like Matrixyl or Argireline?
A: While all are effective, their mechanisms differ. Argireline targets muscle contraction to smooth expression lines. Matrixyl primarily signals for collagen production. AHK Tripeptide-3 focuses on broader cellular renewal, collagen stimulation, and acts as a copper carrier, offering a multi-faceted approach to skin rejuvenation.
Q: When can results be expected from products containing AHK?
A: Initial improvements in skin texture and hydration may be noticed within a few weeks. Significant changes in firmness and wrinkle depth typically require consistent use for 8-12 weeks, as collagen remodeling is a gradual process.
Q: Can AHK Tripeptide-3 be combined with other active ingredients?
A: Absolutely. It works synergistically with other peptides, Hyaluronic Acid for hydration, Vitamin C for antioxidant support, and growth factors. Always ensure formulation compatibility and stability.
Q: How should the raw powder be stored?
A: Store AHK Tripeptide-3 powder in its original container in a cool, dry, and dark place. For extended shelf life, refrigeration is recommended. Keep the container tightly sealed to protect it from moisture.
Contact Us
Elevate your skincare line with the scientifically-backed power of AHK Tripeptide-3. This versatile ingredient is your key to formulating high-efficacy products for the discerning consumer seeking genuine skin renewal.
Contact Xi'an Huilin Biological Technology Co., Ltd. today to request a sample, check current stock, or consult with our technical experts for formulation support. E-mail: ella.zhang@huilinbio-tech.com.
References
- Pickart, L., & Margolina, A. (2018). Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. (Note: GHK-Cu is a closely related and extensively studied copper peptide complex. The biological activities of AHK are similar and often referenced in the context of this family of peptides).
- Maquart, F. X., et al. (1990). Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+.
- Simeon, A., et al. (2000). The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures.
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