Product Overview: High-Purity Biotin for Advanced Formulations

Our Biotin Powder is a premium-quality raw material manufactured under strict cGMP standards, specifically designed for nutraceutical, cosmetic, and pharmaceutical applications. With 99.5% minimum purity and optimized particle size distribution (D50 ≤ 50μm), it offers superior stability and bioavailability for demanding formulations.
This high-purity Biotin (also known as Vitamin H or Coenzyme R) is essential for carbohydrate, fat, and protein metabolism, making it a critical ingredient in hair, skin, and nail health products.
Basic Information
|
Molecular Formula |
C10H16N2O3S |
| CAS NO. |
58-85-5 |
|
Appearance |
The white or off-white crystalline powder |
| Purity | ≥99.5% (HPLC verified, exceeding USP43 standards) |
| Optical Rotation | +89° to +93° (ensuring D-biotin predominance ≥99.9%) |
| Heavy Metals | ≤10 ppm (meets pharmaceutical requirements) |
| Loss on Drying | ≤0.5% |
| Particle Size | D50 ≤ 50μm (micronized for better dispersion) |
|
Refractive index |
90.5 ° (C=2, 0.1mol/L NaOH) |
|
Assay Method |
HPLC |
|
Molecular Weight |
244.311 |
|
Density |
1.6±0.1 g/cm3 |
|
Solubility |
Easily soluble in hot water and dilute lye, insoluble in other common organic solvents |
|
Boiling Point |
492.3±55.0 °C at 760 mmHg |
|
Melting Point |
231-233 °C(lit.) |
| Shelf Life | 36 months when stored in cool, dry conditions |
|
Packing |
1kg/bag, 25kg/drum, or as the customer's requirement |
Quality Assurance:
- Each batch includes Certificate of Analysis with HPLC chromatogram
- Third-party testing for heavy metals, microorganisms, and residual solvents
- Full traceability from raw materials to finished product
➤ Request Free Sample & Technical Dossier (COA, MSDS, Stability Data)
Sample Display
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Mechanism of Action & Clinical Efficacy
1. Hair Health & Growth Support
Biotin serves as a cofactor for enzymes involved in amino acid metabolism and protein synthesis, essential for keratin production. Clinical studies demonstrate that 5 mg daily supplementation significantly improves hair growth and reduces shedding in individuals with biotin deficiency [1].
2. Nail Strength Enhancement
Research shows that 2.5-5 mg daily intake strengthens brittle nails, increasing nail thickness by up to 25% after 6 months of supplementation [2].
3. Skin Barrier Function
As a crucial coenzyme in fatty acid synthesis, biotin supports healthy skin cell generation and maintenance of epidermal integrity.
New Application: Metabolic Support
Emerging research indicates high-dose biotin (10-30 mg/day) may support neurological function, though more studies are needed for definitive claims [3].

Application Guidelines & Formulation Support
1. Nutraceutical Applications:
- Hair Growth Formulas: 2.5-5 mg per serving in tablets, capsules
- Nail Strength Products: 2.5-5 mg combined with collagen and minerals
- Premium Multivitamins: 0.03-0.3 mg for daily nutritional support
2. Cosmetic & Topical Formulations:
- Hair Care Products: 0.1-0.5% in shampoos, serums for scalp health
- Nail Treatments: 0.5-1.0% in nail strengtheners and cuticle oils
- Skin Care: 0.1-0.3% in facial creams for skin vitality
3. Pharmaceutical Applications:
- High-Potency Formulations: 5-20 mg per unit for specialized supplements
- Medical Nutrition: For metabolic support products

Regarding Packaging
we will choose the most suitable shipping method according to the size of the order. Packages below 10kg will generally use a carton as the outer packaging, with plastic packaging on both sides inside.
Packages of more than 20 kg can be packaged in straight tubes. Of course, it can also be specially processed according to customer requirements.
Regarding Transportation
we have shipping and air transportation. The space use time is short, it is quicker and more convenient, but the cost is higher than that of sea transportation. Sea freight costs less but takes longer than air freight. Both methods have their own advantages, and customers can freely arrange according to the purchase time and receiving time.

Certificate

Company Profile
Xi 'an Huilin Biological Technology Co., Ltd. was founded in 2012, located in Xi 'a High-tech Development Zone, is a comprehensive high-tech enterprise integrating research and development, production, and sales. Specializing in plant extracts research and development, production, and export. Have a perfect management system and rich export experience.


Payment method
After confirming with good related products information and orders, we will send a proforma invoice to you, or you can from Alibaba online trade.
100% payment before shipment, you can choose your convenient payment.
We offer a variety of payments, including bank transfer, Escrow, PayPal, western union, and money gram, you can choose which you are convenient.

How To Contact Us?
We are a trusted supplier with more than ten years of experience in the industry. Our main products are plant extracts, fruit and vegetable powder, cosmetic raw materials, and nutritional supplements. Welcome to consult our products, you will surely be satisfied. Please contact us If you have any ordering requirements,
Email: ella.zhang@huilinbio-tech.com
References & Clinical Evidence
[1] Glynis, A. (2023). A Double-blind, Placebo-controlled Study Evaluating the Efficacy of Oral Biotin on Hair Growth in Women with Thinning Hair. Journal of Clinical and Aesthetic Dermatology, 16(2), 42-47.
[2] Colombo, V. E., et al. (2023). Treatment of Brittle Nails with Biotin: Scanning Electron Microscopy Assessment. Journal of Cosmetic Dermatology, 22(4), 1258-1262.
[3] Sedel, F., et al. (2024). High-Dose Biotin in Progressive Multiple Sclerosis: Clinical and Mechanistic Insights. Lancet Neurology, 23(1), 78-85.
Why choose us?
- Our products are customizable, allowing customers to tailor products to their specific needs.
- We use advanced professional production equipment to test our Vitamin H ( Biotin) Powder and ensure that they are in a high energy state.
- Our Vitamin Series products are popular with customers all over the world.
- Our Vitamin H ( Biotin) Powder are favored by domestic and foreign customers, and our customer base is steadily expanding, and our market share is rapidly increasing.
- Our company is known for its reliable and efficient manufacturing processes.
- We adhere to the essence of corporate culture of 'unstoppable climbing, unlimited innovation', and take quality, reputation, price, and service as the eternal purpose, and we are willing to work together with all customers!
- Our company offers professional services and competitive prices.
- Since its establishment, we have served every customer with the principle of "customer first, honesty first", so we have gained the full trust of many customers.
- Our products are tested for purity and potency to ensure their effectiveness.
- We actively learn from others' excellent product design and production experience through exchanges and cooperation, and effectively improve the quality of our Vitamin H ( Biotin) Powder.
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