Can andrographis Extract Powder be taken daily?

Product introduction of andrographis paniculata extract powder

Andrographis Extract Powder is white powder. Andrographis paniculata(Burm.f.)Nees) is the whole grass or leaf of the Andrographis paniculata(burm. f.) nees. Also known as spring lotus autumn willow, one see joy, olive kernel lotus, bitter gall, golden herb, golden ear hook, Indian grass, bitter grass and so on. It has the effect of clearing heat and detoxifying, reducing inflammation, detumescence and relieving pain. Treating bacillary dysentery, urinary tract infection, acute tonsillitis, enteritis, pharyngitis, pneumonia and influenza, external use can treat boils swollen poison, trauma infection, etc. Mainly produced in Guangdong, Fujian and other provinces, central China, North China, Northwest and other places also introduced

Andrographis has anti-inflammatory and detoxification effects. It has been clinically used in a variety of infectious diseases, including traumatic infection, furuncle, carbuncle, erysipelas, upper respiratory tract infection, acute and chronic tonsillitis, acute and chronic pharyngitis, acute and chronic bronchitis, acute dysentery, acute gastroenteritis, urinary tract infection, endometritis, pelvic inflammatory disease, otitis media, periodontitis, etc., all of which have different degrees of efficacy. Preparation and usage: At present, it has been made into injection, oral capsules or tablets, the dosage must be different depending on the different contents of the preparation produced in different places. For general inflammation and infection, Andrographolium paniculata hay 2~3 money decoction, 1 dose a day; Or tablets (each piece is equivalent to 1g crude drug) for internal administration, 4~8 tablets each time, 3~4 times a day. For suppurative skin infection wound, andrographolium paniculata leaves can be ground to make 1:4 water solution and soak gauze for external application. Local application of ear drops can be made for suppurative otitis media.

what is andrographis extract used for

1.Hepatoprotective effect. Andrographolide prevents BHC-induced gamma-glutamyl transpeptidase, glutathione S-transferase enzyme activity and lipid peroxidation. The activities of antioxidant enzymes such as superoxide dismutase, catalase, glutathione peroxidase and glutathione peroxidase are decreased under BHC. The administration of andrographolide showed protective effects on the activities of superoxide dismutase, catalase, glutathione peroxidase, and glutathione reductase as well as maintenance of glutathione levels. The activity of lipperoxidase also decreased. These results demonstrate the antioxidant and liver protection functions of Andrographis paniculata.

2.Relieve cold symptoms. A study measuring the efficacy of andrographolide versus placebo in reducing symptoms of the common cold. The effect of andrographolide was measured at day 0,2, and 4 in a cohort of 158 adult men and women. The group receiving andrographolide on day 2 showed a reduction in some related symptoms, and by day 4 the same group of patients had a significant reduction in all symptoms compared to the group receiving placebo. Overall, the effect of andrographolide on reducing the rate of infection and intensity of uncomplicated common cold symptoms was significant within the first two days of treatment, and no adverse effects were observed.

3.andrographis Extract Powder have function of  Hypoglycemic activity. To date, andrographolide is known as a hepatoprotective agent, an antiplatelet agent, and an antithrombotic agent. In experiments, its hypoglycemic effect has been tried in many ways. 10mg/kg of andrographis water extract prevented significant (P<0.001) hyperglycemic induction induced by oral administration of 2mg/kg of body weight glucose. But it failed to treat adrenaline-induced hyperglycemia. Long-term use of andrographolide (6 weeks) also failed to demonstrate some "rapid glycemic effect". So andrographolide may block glucose uptake in the gut.

4. Contraceptive efficacy. The contraceptive effect of andrographolide was found in mice under different research environments. When andrographolide was mixed with animal feed (mouse pellets) at a dose of 2g/kg daily and given to female mice daily for a period of 6 weeks, none of the female mice paired with unmedicated and proven fertile male rats became pregnant (100%). On the other hand, most of the controlled females (95.2%) who did not receive the drug and were paired with the same males in the experimental group became pregnant and continued to give birth to normal size and number of pups (typically 5-6) in six subsequent pairs.

5. Cardiovascular effects. To observe the effects of androholide on nitrous oxide, endothelin, cyclic guanylate, lipid peroxide, and superoxide dismutase in an experimental atherosclerotic rabbit model established by supplementing a high cholesterol diet with bovine serum albumin pellet injections. Rabbits were randomly divided into control model group and andrographolide treatment group. Blood samples were collected before 4 and after 8 weeks after the corresponding treatment. Compared with the model group, the activities of nitrous oxide, cyclic guanosine, and superoxide dismutase increased in the androholide treated group before and after 4 and 8 weeks, while lipid peroxide and endothelin decreased. It can be concluded that andrographolide has the function of antioxidant, protecting endothelial function and maintaining nitrous oxide/endothelin balance.

Security of andrographis paniculata leaf extract

An acute toxicity study reported high LD50 levels in Andrographis paniculata. Cannot detect. A chronic toxicity study in dogs showed no pathological changes after taking 15 times the clinical dose of andrographolide. Despite increased concern about its contraceptive activity in animal studies, andrographolide has not been found to have any side effects in human studies. In one study, participants' changes in liver function, blood cell count, kidney function and other standard laboratory measures of toxicity were monitored. But no problems were found.

Chemical composition of andrographis extract

Although two Chinese publications list a wide range of 6 additional ingredients, the main active ingredient of andrographolide is andrographolide, and other components besides andrographolide include neoandrographolide; Eleminolide A,B and C; 14-deoxygen-11-oxidized andrographolide and 14-deoxygen-11-dehydrated andrographolide.

How to contact us?

We are a company with many years of sales experience in the plant extract industry. After years of operation, we have a wide range of products, such as fruit and vegetable powder, cosmetics, tablet candy and other products. We are a professional raw material supplier. Currently, our company is selling andrographis Extract Powder in bulk at a cheap price, which is widely used in health care products, medicine, cosmetics and other fields. Those who need to make health care products can buy this raw material. Meanwhile, our products are sold directly from manufacturers, so the quality is guaranteed. You can buy with confidence.

If you want to buy or are interested in it, you can visit our international website or send an email to our work email address ella.zhang@huilinbio-tech.com. We will reply you as soon as you see the message. In addition, you can also come to the offline field investigation, our company is located in Fengze Science Park B, 170 Yanta District West Street, Xi 'an, Shaanxi Province, Room 706, welcome to your arrival.