Introduction of Paeonol
Paeonol is the primary bioactive phenolic compound extracted from the root bark of the Moutan peony (Paeonia suffruticosa), a plant with a well-documented history of use in Traditional Chinese Medicine spanning over 1,500 years. As a white to off-white crystalline powder with a purity of ≥99% verified by HPLC, paeonol has been extensively studied for its remarkable anti-inflammatory, antioxidant, antibacterial, analgesic, and tyrosinase-inhibiting properties.
Unlike single-application ingredients, paeonol is a multi-industry active compound with proven value across pharmaceuticals, cosmetics, functional foods, and agricultural applications. Its versatility, combined with high purity and consistent quality, makes it a preferred choice for formulators and manufacturers seeking scientifically backed natural active ingredients.
Basic information
| Parameter | Specification |
|---|---|
| Assay (HPLC) | ≥ 99% |
| Appearance | White to off-white crystalline powder |
| Odor | Characteristic aromatic |
| Melting Point | 49–52°C |
| Particle Size | 100% through 80 mesh |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Total Plate Count | ≤ 1,000 CFU/g |
| Yeast & Mold | ≤ 100 CFU/g |
| E. coli | Negative |
| Salmonella | Negative |
| Shelf Life | 24 months |
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Benefits of paeonol
Paeonol exhibits a broad spectrum of scientifically validated pharmacological activities:
1. Anti-Inflammatory
Paeonol effectively suppresses key inflammatory mediators, reducing erythema, redness, and swelling. It alleviates tissue damage and relieves inflammatory responses in various conditions, making it valuable for both topical and systemic applications.
2. Antioxidant
Scavenges free radicals and neutralizes oxidative stress, protecting cells and tissues from environmental damage and supporting healthy aging.
3. Antibacterial & Antimicrobial
Demonstrates broad-spectrum antibacterial activity against various pathogens, including Staphylococcus aureus, Escherichia coli, and acne-causing bacteria.
4. Tyrosinase Inhibition
Exhibits strong inhibitory activity against tyrosinase – the key enzyme in melanin production – making it effective for skin brightening and pigmentation control.
5. Analgesic
Shows pain-relieving properties in various inflammatory pain models.
6. Antipyretic
Demonstrates fever-reducing activity in experimental models.
Application of paeonol
1. Pharmaceuticals & Traditional Medicine
Paeonol is a well-established active ingredient in both Traditional Chinese Medicine and modern pharmaceutical research.
Traditional Applications:
- Treatment of pain, inflammation, and skin disorders
- Used in formulations for rheumatism, dysmenorrhea, and allergic conditions
Modern Pharmaceutical Research:
- Anti-inflammatory drug development
- Cardiovascular protection
- Neuroprotective applications
- Immunomodulatory research
- Antitumor research
Forms:
Tablets, capsules, ointments, plasters, injections
Note: Finished pharmaceutical products containing paeonol require full regulatory approval (e.g., FDA NDA, EMA, NMPA) in their respective markets. This raw material is supplied for research and manufacturing purposes only.
2. Cosmetics & Personal Care
Paeonol is a highly valued active ingredient in premium skincare formulations due to its multi-target benefits.
Key Cosmetic Benefits:
- Skin brightening – Inhibits tyrosinase activity, reducing melanin production and promoting even skin tone
- Anti-inflammatory & soothing – Reduces redness, irritation, and hypersensitivity
- Antibacterial & acne control – Helps inhibit acne-causing bacteria and supports clearer skin
- Antioxidant protection – Protects skin from environmental stressors and premature aging
- UV protection support – Demonstrates UVB absorption potential
Application Forms:
- Brightening serums and essences
- Anti-acne treatments and spot correctors
- Soothing creams and lotions for sensitive skin
- Anti-aging and firming formulations
- Sun protection products
- Hair care and scalp treatments
Recommended Concentration:
0.01% – 0.2% in finished formulations, depending on application type.
3. Food & Nutraceuticals
Paeonol is gaining recognition as a functional ingredient in food and supplement applications.
Nutraceutical Applications:
- Cardiovascular health supplements
- Anti-inflammatory wellness products
- Antioxidant formulations
- Immune support supplements
Food Applications:
- Natural preservative – Extends shelf life by inhibiting microbial growth
- Natural antioxidant – Prevents lipid oxidation in oils and fatty foods
- Flavor ingredient – Contributes aromatic notes in certain applications
- Recommended Usage: Varies by application; food-grade specifications available upon request.
4. Agricultural Applications
Emerging research supports paeonol's potential in sustainable agriculture:
- Plant growth regulator – Promotes crop growth and development
- Natural pesticide – Demonstrates activity against plant pathogens and pests
- Post-harvest preservation – Inhibits spoilage microorganisms in fruits and vegetables
5. Research & Development
Paeonol serves as an important research tool in academic and industrial laboratories:
- Model compound for studying anti-inflammatory and antioxidant pathways
- Reference standard for quality control of peony-derived products
- Lead compound for drug discovery and development
Safety information
Customs Code: 2914509090
WGK Germany: 3
Danger class code: R20/21/22; R36/37/38
Safety: S26-S28-S36/37/39-S45
RTECS number: RT1215000
Dangerous goods mark: Xn: Harmful
Certificate

Our strengths
(1) We are a very powerful company with advanced technology, perfect equipment and professional personnel
(2) High-quality products can supply high-quality and stable products for a long time
(3) Professional team, to provide a full range of services and after-sales follow-up services
Our packing

Our transportation
(1) Express: suitable for less than 50 kg, aging 3-4 days, high cost, door-to-door service, easy to pick up goods
(2) air transport: suitable for more than 50 kg, limitation of 4-5 days, high cost, airport-to-airport, professional responsible person
(3) Shipping: suitable for more than 500 kg, 15-45 days of aging, low cost, need to port to port a professional responsible person

Contact us
If you need paeonol or other products, please contact ella.zhang@huilinbio-tech.com
Why choose us?
- We are committed to providing our customers with the highest level of service possible.
- The influence of enterprise managers plays a vital role in the survival and development of enterprises.
- We are experts in the Cosmetic Raw Materials industry.
- The company has excellent employees, advanced technology, sophisticated equipment and strict management, which are the foundation for the company to continue to grow and develop.
- We work tirelessly to ensure our customers always receive the best products and services.
- We sincerely implement with action, seek quality, stress service and based on the industry, we strive to create the industry brand recognized by the majority of customers.
- We are passionate about providing our customers with high-quality Cosmetic Raw Materials.
- We have a sales team composed of experienced sales staff, which is the marketing pillar to ensure that our products reach consumers.
- We understand the importance of listening to our customers' needs.
- In today's era of opportunities and challenges, our company will continue to serve our customers wholeheartedly with more serious and responsible professionalism, high-quality Paeonol, reasonable prices and perfect services.
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