Sodium Carboxymethyl Beta-Glucan Powder

Sodium Carboxymethyl Beta-Glucan: The Advanced, Water-Soluble Skin Defender

Sodium Carboxymethyl Beta-Glucan is a high-performance, chemically modified polysaccharide derived from the cell walls of baker's yeast (Saccharomyces cerevisiae). Through a proprietary carboxymethylation process, natural beta-glucan is transformed into a highly water-soluble sodium salt, overcoming the solubility limitations of its raw form and unlocking its full potential for advanced cosmetic formulations. This white to off-white powder is renowned for its exceptional immunomodulatory and antioxidant properties, making it a cornerstone ingredient for anti-aging, soothing, and barrier-repair skincare products.

The primary sodium carboxymethyl beta-glucan skin benefits stem from its ability to activate the skin's innate immune system, particularly Langerhans cells, thereby enhancing the skin's resistance to environmental stressors, reducing sensitivity, and promoting a healthier, more resilient complexion.

Sodium carboxymethyl beta-glucan in skin care works through a multifaceted biological mechanism:

1. Immuno-Defense Activation & Barrier Support: As a potent biological response modifier, it binds to specific receptors on immune-competent skin cells like Langerhans cells and keratinocytes. This binding "trains" the skin's defense system, enhancing its tolerance to aggressors (like pollution and UV stress) and reducing reactivity, which is crucial for sensitive or compromised skin.
2. Powerful Antioxidant Protection: It demonstrates significant antioxidant activity, helping to neutralize free radicals generated by UV radiation and environmental pollution. This action protects skin cells from oxidative damage, a key driver of premature aging.
3. Promotion of Skin Repair & Firmness: Research indicates it can accelerate wound healing and help repair UV-induced skin damage, such as erythema (redness). By stimulating skin metabolism and collagen support, it contributes to improved skin elasticity and firmness.
4. Superior Hydration & Film-Forming: The carboxymethyl groups grant excellent water-binding capacity, providing long-lasting hydration. It also forms a gentle, protective film on the skin, aiding in moisture retention and strengthening the skin barrier.

Sodium carboxymethyl beta-glucan for skin is versatile and suitable for a wide range of leave-on and rinse-off products.

1. Suggested Use Concentration: 0.05% - 5.0%.

• For general moisturizing and conditioning: 0.05% - 0.5%.
• For targeted anti-aging, soothing, or barrier repair serums and creams: 0.5% - 2.0%.
• The ingredient is listed in China's Inventory of Used Cosmetic Ingredients with a maximum historical use level of 5% in leave-on products.

2. Solubility & Incorporation Method:

• Highly water-soluble. For optimal results, it is recommended to disperse the powder in a small amount of propylene glycol or glycerin to form a slurry, then add this slurry to the water phase of the formulation at room temperature with moderate agitation. Avoid adding directly to high-temperature water phases (>60°C) to prevent potential clumping.

3. Compatibility:

• Compatible with most cosmetic ingredients, including anionic, nonionic, and cationic surfactants, as well as various oils and emollients. Always conduct compatibility tests in final formulations.

4. Product Types:

• Anti-aging & Firming Serums/Creams
• Sensitive Skin Soothing & Repair Treatments
• Post-Procedure (e.g., laser, peeling) Recovery Creams
• Hydrating Toners & Essences
• Sun Care and After-Sun Products
• Premium Makeup Foundations & Primers

The safety of this ingredient is well-substantiated by scientific studies and regulatory recognition.

• Comprehensive Safety Assessment: A pivotal 28-day repeated dose oral toxicity study in rats established a No Observed Adverse Effect Level (NOAEL) of 2000 mg/kg body weight/day, the highest dose tested. This sodium carboxymethyl beta glucan noael data indicates a very wide safety margin for topical cosmetic use. Additionally, it showed no mutagenic activity in a bacterial reverse mutation test.
• Global Regulatory Status:

 USA: Reviewed and deemed safe for use in cosmetics by the Cosmetic Ingredient Review (CIR) Expert Panel. Its safety profile supports its use in products from brands like Paula's Choice, which prioritizes scientifically backed ingredients.

 EU: Listed in the CosIng database as a viscosity controller and binding agent.

 China: Officially listed in the Inventory of Used Cosmetic Ingredients (IECIC 2021), entry number 06536.

 EWG Skin Deep® Database: Based on its robust safety data, it typically receives a low hazard rating, reflecting its clean safety profile.

• Non-comedogenic: Due to its water-soluble nature and molecular size, it is considered to have a very low risk of clogging pores.

You can contact our email: ella.zhang@huilinbio-tech.com. We are looking forward to cooperating with you!

Why choose us?

• Our focus on quality and service is what sets us apart.
• We are a modern enterprise integrating scientific research, development, production, sales and service, specializing in the production of Sodium Carboxymethyl Beta-Glucan series products.
• Our outstanding products and service are a testament to our hard work and dedication.
• Honesty and compliance with the law are not only our most basic values for a long time, but also an important guarantee for us to win one success after another.
• Our prices may be competitive but our quality is always superior.
• We take the needs of customers as the focus, listen to the voices of customers, and transform customer needs into product requirements in a timely manner.
• Our products are specifically designed to meet the needs of the cosmetic industry.
• The systematic products and solutions we have developed with independent intellectual property rights are extremely competitive in the market.
• We are here to help you succeed in your business.
• All over the world efficient network purchase and sale way, to provide you with convenient and fast service.

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