Premium Skin-Brightening & Antioxidant Active Ingredient
Raspberry Ketone Glucoside (RKG) is a high-purity, naturally derived cosmetic active ingredient and flavor precursor extracted from the raspberry fruit (Rubus idaeus L.). This white, water-soluble crystalline powder is prized for its potent skin-brightening and antioxidant properties. By targeting multiple pathways in the melanogenesis process, it effectively inhibits unwanted pigmentation, evens skin tone, and provides defense against oxidative stress, making it a superior and safer choice for modern cosmetic and nutraceutical formulations.
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Key Product Specifications
| Attribute | Specification |
|---|---|
| INCI Name | Raspberry Ketone Glucoside |
| Chemical Name | 4-[4-(β-D-Glucopyranosyloxy)phenyl]-2-butanone |
| CAS Number | 38963-94-9 |
| Molecular Formula | C₁₆H₂₂O₇ |
| Molecular Weight | 326.34 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (by HPLC) |
| Solubility | Highly soluble in water, soluble in polar organic solvents like ethanol. |
| Recommended Usage | 1% - 3% in final cosmetic formulations. |
| Storage & Stability | Store sealed, protected from light at 4°C. Stable for 24 months. |
Scientific Mechanism: How Raspberry Ketone Glucoside Works
Raspberry Ketone Glucoside delivers its skin-brightening effects through a multi-targeted biological approach, which is more comprehensive than single-pathway inhibitors:
- Direct Tyrosinase Inhibition: RKG suppresses the activity of tyrosinase, the key enzyme responsible for the first step in melanin (pigment) synthesis.
- Regulation of Melanogenic Signaling: It activates the IL-6/JAK1/STAT3 cellular pathway. This activation leads to the downregulation of the master regulator MITF and its downstream target genes, including TYR (tyrosinase) and TYRP1, effectively putting a brake on the entire melanin production machinery.
- Potent Antioxidant & Anti-Inflammatory Action: RKG is an excellent scavenger of nitric oxide (NO) free radicals. Excess NO, often generated by UV exposure and inflammation, can damage skin, accelerate aging, and itself stimulate melanogenesis. By neutralizing NO, RKG protects skin cells and indirectly further suppresses pigment formation.
This combination of direct enzyme inhibition, genetic regulation, and antioxidant protection makes RKG a highly effective and well-rounded active for treating hyperpigmentation.
Proven Efficacy & Benefits
The multi-faceted mechanism of RKG translates into significant, measurable skin benefits, supported by both in-vitro and clinical studies:
- Clinically Demonstrated Skin Brightening: Human efficacy trials have shown that a 3% concentration of RKG significantly increases skin luminance (L-value) and improves overall skin tone. User satisfaction in these studies exceeded 90% for improvements in skin brightness, smoothness, and hydration.
- Superior Efficacy Compared to Arbutin: Research indicates that RKG exhibits a stronger inhibitory effect on melanin synthesis than the commonly used ingredient arbutin. Furthermore, unlike arbutin, RKG does not carry the risk of degrading into hydroquinone, making it a safer long-term option.
- Powerful Antioxidant Protection: Its ability to scavenge nitric oxide and other free radicals helps protect the skin from environmental damage, reducing oxidative stress that contributes to photoaging and uneven pigmentation.
- Soothes and Improves Skin Resilience: By mitigating inflammatory pathways linked to UV exposure, RKG can help calm skin and reduce the appearance of post-inflammatory redness.
Versatile Applications
Raspberry Ketone Glucoside is a versatile ingredient suitable for a wide range of product categories targeting skin clarity and health:
- Cosmetic & Skincare Products:
Brightening Serums & Ampoules: High-potency treatments for dark spots and uneven tone.
Daily Moisturizers & Creams: For overall luminosity and preventative care.
Targeted Spot Correctors: For concentrated application on hyperpigmentation.
Anti-Aging Formulations: Combats both pigmentation and oxidative stress for a more youthful appearance.
- Synergistic Formulations: RKG works exceptionally well in combination with other actives. A serum featuring kojic acid and raspberry ketone glucoside leverages complementary mechanisms for enhanced brightening. It also pairs effectively with vitamins C and E, ferulic acid, and niacinamide.
- Nutraceutical & Food Applications: As the glucosidic precursor to raspberry ketone, it finds use as a flavor precursor and functional ingredient in the food and supplement industries.
Frequently Asked Questions (FAQ)
Q: What's the difference between Raspberry Ketone and Raspberry Ketone Glucoside (RKG)?
A: Raspberry ketone is the volatile aromatic compound that gives raspberries their signature scent. Raspberry Ketone Glucoside is a naturally occurring, non-volatile sugar derivative (glucoside). RKG is the form used in cosmetics for its skin benefits and water solubility, not primarily for fragrance.
Q: How does RKG compare to kojic acid or vitamin C?
A: While all three are tyrosinase inhibitors, they work via different supporting mechanisms. RKG's unique advantage is its additional action of regulating melanin production at the genetic level (via the MITF pathway) and its potent nitric oxide scavenging ability. It is often used with these ingredients for a synergistic, multi-angle brightening effect.
Q: At what concentration is RKG most effective?
A: For significant brightening effects, a concentration of 1% to 3% in the final formulation is recommended based on clinical studies. Higher concentrations within this range are typically used for intensive treatments.
Q: Can RKG be used in all product types?
A: Yes, thanks to its high water solubility and stability across a broad pH range, it is easily incorporated into aqueous solutions, serums, emulsions, creams, and gels.
Q: Is RKG safe for long-term use?
A: Yes. Its favorable safety profile and lack of risky metabolites (like hydroquinone from arbutin) support its safety for long-term, daily use in skincare routines.
Transport
(1) 1-50 kg, express delivery is recommended. For example: DHL/fedex, etc
(2) 51-500 kg, recommended air freight, fast aging
(3) More than 500kg, recommended sea transportation, low freight cost
Contact information
If you need this product or know more, you can contact ella.zhang@huilinbio-tech.com
Related questions
(1) Is there any discount?
There are different discounts for different quantities.
(2) What is the minimum order quantity of Raspberry ketone glucoside?
Our minimum order quantity is 1 kg. But usually we accept smaller quantities, such as 100g, with 100% payment of the sample fee.
(3) Do you provide product reports?
Yes. We will provide you with a product analysis report before shipment.
(4)What about the delivery time?
Generally, 3-5 days after confirmation of payment.
Why choose us?
- Our products and services are designed to meet the needs of your business.
- Our concentrate on should be to consolidate and enhance the quality and service of present products, meanwhile consistently produce new products to meet unique customers' demands for Raspberry Ketone Glucoside.
- Our experienced professionals work tirelessly to ensure quality and efficiency.
- In order to enhance the competitiveness of our company, we have to continuously improve the quality of our Raspberry Ketone Glucoside.
- With an emphasis on quality and service, we provide the best Cosmetic Raw Materials in the market.
- Our corporate style is: quick response, decisive decision, strict implementation, and sincere cooperation.
- We are here to help you succeed in your business.
- Our pursuit goals is 'for society, customers, employees, partners and enterprises to seek reasonable benefit'.
- Our success is built on our customers' satisfaction.
- Looking forward to working with you Now!
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