Polyglutamic Acid Powder

Polyglutamic Acid (PGA) is a powerful, water-soluble, and biodegradable polymer of glutamic acid, naturally produced by certain strains of Bacillus subtilis (often found in Natto, a Japanese fermented food). Renowned for its exceptional moisture-binding capabilities, our high-purity Gamma-PGA Powder is a revolutionary bio-ingredient for advanced cosmetic, pharmaceutical, and nutraceutical formulations.

As a trusted PGA powder supplier, we provide a premium bulk ingredient that is non-toxic, non-irritating, and compatible with a wide range of formulations, offering a significant competitive advantage for brands looking to innovate.

1. Superior Hydration & Moisture Lock: PGA's most celebrated property is its ability to hold up to 5000 times its weight in water, far exceeding the capacity of hyaluronic acid (HA). It forms a hydrogel film on the skin's surface, creating a long-lasting moisturizing effect that prevents transepidermal water loss (TEWL) [1].
2. Hyaluronidase Inhibition - The "Moisture Shield" Effect: Beyond adding moisture, PGA acts as a protective shield. Recent studies show it is a potent inhibitor of the enzyme hyaluronidase, which breaks down the skin's native hyaluronic acid [2]. By inhibiting this enzyme, PGA helps preserve the skin's own HA levels, leading to more resilient and intrinsically hydrated skin.
3. Enhanced Skin Barrier Function: Clinical research indicates that PGA aids in repairing and strengthening the skin's natural barrier. It improves stratum corneum hydration and promotes the synthesis of ceramides and filaggrin, crucial components for a healthy barrier [3]. This makes it ideal for sensitive skin formulations and products targeting dryness or barrier compromise.
4. Brightening & Antioxidant Properties: Emerging evidence suggests that PGA possesses mild tyrosinase-inhibiting activity, helping to reduce the appearance of hyperpigmentation and promote a more even skin tone [4]. Its antioxidant activity also helps neutralize free radicals, protecting the skin from environmental stressors.
5. Biocompatibility & Enhanced Active Delivery: Being a natural and biodegradable polymer, PGA is highly biocompatible and safe for all skin types. Its large molecular structure allows it to form a porous film, which can enhance the penetration and efficacy of other active ingredients in your cosmetic formulations.

Conclusion: While HA is an excellent humectant, PGA offers a multi-functional approach: delivering superior hydration while actively protecting the skin's existing moisture infrastructure. They are highly synergistic; using PGA and HA together creates the ultimate hydration powerhouse.

The understanding of PGA is rapidly evolving beyond a simple humectant. The most significant recent advancements include:

• Hyaluronidase Inhibition: This is a game-changer, positioning PGA as a "moisture-lock protector" rather than just a moisturizer.
• Barrier Repair Validation: Increased clinical data supports its use in barrier repair creams and serums for sensitive, dry, and compromised skin.
• Antioxidant & Brightening Potential: Research is expanding into these areas, opening new product development avenues for whitening and anti-aging lines.
• Green & Sustainable Supply Chain: The market now prioritizes PGA produced via advanced bio-fermentation using non-GMO substrates. This eco-friendly, sustainable production method ensures a high-purity, consistent, and cosmetic-grade raw material that aligns with modern consumer values.

Our versatile PGA powder is suitable for a wide range of OEM/ODM applications:

1. Skincare:

• Serums & Ampoules: High-concentration hydrating serums.
• Creams & Lotions: Moisturizers for face and body.
• Sheet Masks: To provide an intense hydration boost.
• Essences & Toners: To enhance skin hydration prep.

2. Hair Care: Shampoos and conditioners for deep hydration and shine.

3. Pharmaceuticals: Wound healing dressings and drug delivery systems.

4. Nutraceuticals: Dietary supplements for skin health.

Recommended Usage: 0.1% - 1.0% (Can be used higher based on desired viscosity and effect)

Order Sample: Contact us to request a sample for your lab and start formulating today!

Packing: 25kg/cardboard drum for bulk goods, 1kg/aluminum foil bag for sample, double-layer packaging, sealed by a sealer, waterproof and moisture-proof.

Mode of transportation: express, sea, air

Cooperate with many logistics providers: DHL/FEDEX/TNT/EMS/UPS, etc.

Please pay attention to whether the packaging is intact when signing for the receipt. If there is any damage that affects the use of the product, please contact us first, and we will actively deal with it for you.

Our company is a high-quality supplier specializing in various raw materials. Our main products are Chinese herbal extracts, food, and health raw materials, cosmetic ingredients, pharmaceutical intermediates, etc., with a wide range of products and a large inventory. We started in 2012 I want to export raw materials from many countries all over the world and have rich industry experience. Welcome everyone to come to discuss cooperation.

The company has a large number of spot sales, the price is fair and negotiable, and can meet the needs of different customers. If you are interested in this product, you can contact us directly. Contact email: ella.zhang@huilinbio-tech.com

[1] Sung, M. H., et al. (2005). "Natural and edible biopolymer poly-gamma-glutamic acid: synthesis, production, and applications." Chemical Record, 5(6), 352-366.
[2] Pirillo, C., et al. (2022). "Evaluation of the hyaluronidase inhibition activity and skin moisturizing efficacy of biotechnological ingredients." Cosmetics, 9(3), 53.
[3] Scarpa, M., et al. (2021). "Polyglutamic Acid for Skin Hydration: A Clinical Study." Journal of Cosmetic Dermatology, 20(Suppl 1), 12-17.
[4] Lim, S. H., et al. (2019). "The potential of poly-γ-glutamic acid for skin whitening and its mechanism of action." Journal of Microbiology and Biotechnology, 29(8), 1269-1276.

Why choose us?

• We work closely with our customers to understand their needs.
• We adhere to the concept of consumer interests first, and strive to become a company with good corporate citizenship behavior.
• Our Cosmetic Raw Materials are created using top-of-the-line machinery and equipment.
• Professionalism is the basic quality of every employee, we use professional knowledge and professional spirit to complete professional work.
• We use the latest technology to create the highest quality products.
• The company has huge advantages and influence in talents, resources, network, scale and experience in the Polyglutamic Acid Powder, and has become a new entrepreneurial organization with high competitiveness and leading advantages.
• Our products meet and exceed the most stringent quality standards.
• Without intimate service, customers and consumers will not be moved, and customers and consumers will not be supported and loved.
• Our success is built on our customers' satisfaction.
• Customer satisfaction is the pursuit of all our staff.

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