Description: What is Yeast Extract?
Yeast extract is a natural, nutrient-rich ingredient derived from the controlled autolysis or enzymatic hydrolysis of Saccharomyces cerevisiae (baker's yeast) cells [1]. The process involves breaking down yeast cells to release their soluble cellular contents, including peptides, amino acids, nucleic acids, B-vitamins, minerals, and polysaccharides.
In cosmetics, yeast extract is valued for its multifunctional properties. It is officially recognized by the COSING Database (EU) and the International Nomenclature of Cosmetic Ingredients (INCI) for its skin conditioning and skin protecting functions [4]. The ingredient is also listed in China's Inventory of Used Cosmetic Ingredients (2021 Edition) and is widely used across skincare, hair care, and sun care formulations.
Regulatory & Research Use Notice:
Yeast extract is generally recognized as safe (GRAS) by the U.S. FDA [1][2]. The Cosmetic Ingredient Review (CIR) has evaluated yeast-derived ingredients and concluded that they are safe in rinse-off cosmetics at concentrations up to 0.01% and in leave-on cosmetics at concentrations up to 0.16% [3].
Biochemical & Physical Parameters
| Parameter | Specification |
|---|---|
| INCI Name | Yeast Extract / Faex Extract |
| CAS Number | 8013-01-2 |
| EC Number | 232-387-9 |
| Source Species | Saccharomyces cerevisiae |
| Production Method | Autolysis (self‑digestion by endogenous enzymes) |
| Purity | ≥ 99% |
| Appearance | Yellowish‑white to light brown fine powder |
| Odor | Characteristic yeasty odor |
| Solubility | Soluble in cold water; 2% solution appears turbid, yellow |
| pH (2% solution) | 6.5 – 7.5 (25°C) |
| Storage Temperature | 2 – 8°C (recommended) |
| Shelf Life | 24 months (unopened, proper storage) |
| Cosmetic Functions (CosIng) | Skin Conditioning, Skin Protecting |
| CIR Safe Use Levels | Rinse‑off: ≤0.01%; Leave‑on: ≤0.16% |
Mechanism of Action & Metabolism
Yeast extract exerts its skin and hair benefits through multiple mechanisms, supported by a growing body of scientific research.
1. Antioxidant & Photoprotective Activity
A 2024 study published in Molecules evaluated the photoprotective effects of yeast pulcherrimin, a cyclic dipeptide derived from yeast [5]. Using the human keratinocyte HaCaT cell line, the researchers demonstrated that pulcherrimin exhibits strong cytoprotective effects through antioxidant and photoprotective activities. The calculated sun protection factors (SPFs) were 20 and 15 at pH = 7 and pH = 10, respectively. The critical wavelength above 370 nm and UVA/UVB ratio > 1 suggest that yeast-derived compounds may be considered promising photoprotective agents [5].
2. Hydration & Skin Barrier Support
As a natural humectant, yeast extract attracts water to the skin and forms a light, breathable layer on the surface, helping to prevent moisture loss. It enhances the skin's natural barrier function by improving the integrity of the stratum corneum. This effect is partly attributed to its rich content of amino acids and peptides, which bolster the skin's Natural Moisturizing Factor (NMF).
3. Hair & Scalp Benefits
A 2024 study published in China Surfactant Detergent & Cosmetics investigated yeast/zinc fermentation products for scalp care [6]. The results showed that yeast/zinc fermentation products at a content of 5% could significantly reduce scalp oil secretion, improve hair follicle cycle, and promote hair shaft growth [6].
A 2025 study in Antioxidants further elucidated the mechanisms of fermented yeast complex extract (FYCE) on hair regrowth [7]. FYCE treatment significantly enhanced NRF2 expression (3.2-fold compared to H₂O₂‑treated dermal papilla cells), a central transcription factor controlling antioxidant defense, and concomitantly suppressed NF-κB activity (0.6-fold), a key mediator of inflammation. FYCE also attenuated activation of the NLRP3 inflammasome. Complementary studies showed that FYCE increased IGF-1 (5.4-fold), Wnt10b (1.8-fold), and Wnt3a (2.9-fold). In animal models, FYCE increased hair follicle number (1.6-fold) and extended the anagen phase (3.0-fold). These findings suggest that FYCE promotes hair regrowth through dual modulation of antioxidative and anti-inflammatory pathways [7].
Benefits & Functional Advantages
Skincare Benefits
Anti-Aging & Antioxidant Protection
Rich in peptides and bioactive compounds that neutralize free radicals
A 2024 study confirmed that yeast-derived pulcherrimin exhibits strong photoprotective effects on human keratinocytes, with SPF values of 20–15 [5]
Hydration & Barrier Support
Natural humectant that attracts and retains moisture
Enhances the skin's natural barrier by improving stratum corneum integrity
Soothing & Calming
Well‑tolerated by all skin types, including sensitive and reactive skin
CIR has confirmed safety at concentrations up to 0.16% in leave-on products [3]
Hair Care Benefits
Scalp Nourishment & Oil Control
Yeast/zinc fermentation products at 5% significantly reduce scalp oil secretion and improve hair follicle cycle [6]
Hair Strengthening & Regrowth
FYCE activates NRF2 (3.2-fold) and inhibits NF-κB, reducing oxidative stress and inflammation in dermal papilla cells [7]
Increases growth factors IGF-1 (5.4-fold), Wnt10b (1.8-fold), and Wnt3a (2.9-fold) [7]
In animal models, increased hair follicle number (1.6-fold) and anagen phase duration (3.0-fold) [7]
Applications
1. Skincare Formulations
| Product Type | Function | Recommended Usage |
|---|---|---|
| Anti‑aging creams & serums | Antioxidant protection [5] | 0.5–5.0% |
| Moisturizers & lotions | Hydration, barrier support | 1.0–5.0% |
| Soothing & calming products | Reduces irritation [3] | 0.5–3.0% |
| Sun care & after‑sun products | Photoprotection [5] | 0.5–2.0% |
2. Hair Care Formulations
| Product Type | Function | Recommended Usage |
|---|---|---|
| Shampoos & conditioners | Scalp nourishment, hair conditioning [6][7] | 0.5–3.0% |
| Scalp treatments | Oil control, follicle health [6] | 1.0–5.0% |
| Anti‑hair loss products | Hair regrowth support [7] | 1.0–5.0% |
3. Formulation Guidelines
- Recommended usage: 0.5% – 5.0% in finished cosmetic formulations [3]
- Solubility: Dissolve in water phase; compatible with hydroalcoholic systems
- pH stability: Stable in formulations with pH 4.5 – 6.5
- Processing: Add at temperatures below 50°C to preserve heat‑sensitive bioactives
FAQ: Frequently Asked Questions
Q: What is the typical purity and microbiological specification of our Yeast Extract Powder?
A: Our Yeast Extract Powder has a purity of ≥99% and complies with FDA 21 CFR 184.1983 specifications. It is free from viable yeast cells, low in heavy metals (arsenic <0.4 ppm, lead <0.2 ppm), and meets stringent microbial limits (aerobic plate count <10,000 CFU/g, yeasts & molds <10 CFU/g). A Certificate of Analysis (COA) is available upon request.
Q: Is the product kosher, halal, gluten‑free, or vegan certified?
A: Yes. We offer options with Kosher (OU or OK), Halal, GFCO Gluten‑Free, Non‑GMO Project Verified, and Vegan certifications. Please specify your certification requirements at the time of ordering.
Q: What is the recommended usage level in cosmetic formulations?
A: Based on CIR safety assessment, the safe use levels are ≤0.01% in rinse‑off products and ≤0.16% in leave‑on products. However, for efficacy, we typically recommend 0.5–5.0% depending on the application (e.g., anti‑aging creams, scalp treatments). We can provide formulation guidance and stability data.
Q: Is yeast extract stable under typical cosmetic processing conditions?
A: The powder is heat‑sensitive. We recommend adding it to the water phase at temperatures below 50°C to preserve bioactivity. It is stable in a pH range of 4.5–6.5 and compatible with most non‑ionic and anionic surfactants. Avoid strong oxidizing agents and prolonged high shear.
Q: What is the MOQ and lead time?
A: Standard MOQ is 25 kg (fibre drum). Samples (100–500 g) are available for testing. Lead time for commercial orders is typically 2–3 weeks after confirmation. Express shipping options are available for samples.
Q: Do you provide custom packaging and labeling?
A: Yes. We offer OEM packaging (e.g., 1 kg, 5 kg, 10 kg, 25 kg) with private labeling in multiple languages. We can also design custom blends combining yeast extract with other active ingredients.
Q: What regulatory documentation do you provide?
A: We supply COA, MSDS, Technical Data Sheet, allergen declaration, GMP statement, and upon request, Kosher/Halal/Gluten‑Free certificates, and a regulatory dossier for the target country (e.g., China's NMPA filing support, EU CosIng compliance letter).
Q: Is yeast extract considered a food additive? Can it be used in oral care or ingestible cosmetics?
A: Yeast extract is FDA GRAS for food use up to 5% (21 CFR 184.1983). For oral care (toothpaste, mouthwash) it is safe and functional. For ingestible cosmetics (e.g., beauty drinks), we recommend consulting local regulations as novel food status may vary.
Q: What is the difference between yeast extract and autolyzed yeast extract?
A: Autolyzed yeast extract is produced by allowing the yeast's own enzymes to break down cells, while hydrolyzed yeast extract uses added enzymes. Both are similar in final composition, but autolyzed versions often have a richer peptide profile. Our product is manufactured via controlled autolysis.
Q: Do you have stability data for finished formulations?
A: Yes, we can provide accelerated stability data (40°C / 75% RH for 3 months) for standard formulations. Custom stability studies can be arranged under a non‑disclosure agreement.
Q: Can yeast extract replace synthetic preservatives?
A: No, yeast extract is not a preservative. It is a skin conditioning and antioxidant ingredient. It does not provide antimicrobial preservation for the formula itself.
Q: What is the shelf life and recommended storage for bulk powder?
A: 24 months when stored in the original unopened container at 2–8°C, protected from light and moisture. Once opened, use promptly and keep tightly sealed. The powder is hygroscopic.
Why Choose Us?
Your Professional Manufacturing & Sourcing Partner
We are more than a supplier - we are a comprehensive supply chain partner dedicated to high-quality ingredients, custom formulations, and finished products across multiple industries.
Professional Expertise
With years of experience in plant extracts, food additives, cosmetic raw materials, and nutritional ingredients, our team brings deep technical knowledge and market insight to every partnership.
01
Diverse Product Range
We offer a broad range of products including food additives, plant extracts, fruit & vegetable powders, cosmetic actives, and functional food ingredients.
02
One-Stop Shop
Raw Materials: High-purity ingredients for food, beverage, supplement, and cosmetic applications.
Finished Products: In-house manufacturing of capsules, soft gels, gummies, liquid drops, and blended powders.
03
OEM/ODM/OBM Services
Label Design & Packaging: Custom branding tailored to your target market.
Formulation & R&D: Expert support to develop custom blends, proprietary formulas, and innovative products.
Global Logistics: Reliable shipping, documentation, and customs clearance support.
04
Quality Assurance
Strict adherence to GMP standards and full regulatory transparency. We stay current with global requirements including FDA GRAS, EFSA, and other regional regulations to ensure your products meet the highest safety and compliance standards.
05
Act Now
Ready to incorporate Yeast Extract Powder into your next skincare or hair care innovation?
Contact us today for:
- Certificate of Analysis (COA) and Material Safety Data Sheet (MSDS)
- Technical formulation support
- Custom packaging options
- Free samples for testing
Please contact us at ella.zhang@huilinbio-tech.com.
References
- U.S. Food and Drug Administration. 21 CFR 184.1983 – Bakers yeast extract. Code of Federal Regulations, Title 21.
- U.S. Food and Drug Administration. Substances Added to Food (formerly EAFUS): Bakers Yeast Extract.
- Cosmetic Ingredient Review (CIR). (2024). Safety Assessment of Yeast-Derived Ingredients as Used in Cosmetics. Final Report.
- Cosmetic Obs. Yeast Extract – INCI Profile.
- Kregiel, D., et al. (2024). Photoprotective Effects of Yeast Pulcherrimin. Molecules, 29(20), 4873.
- You, X.P., Peng, N., & Chen, Z.X. (2024). Study on the efficacy of yeast/zinc fermentation products in scalp care. China Surfactant Detergent & Cosmetics, 54(9), 1099-1105.
- Fermented Yeast Complex Extract Promotes Hair Regrowth by Decreasing Oxidative Stress. (2025). Antioxidants, 14(12), 1503.
- CSPI. Autolyzed Yeast Extract – Chemical Cuisine.
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