Stable S-Adenosylmethionine (SAMe) Powder 99% | Premium Methyl Donor for Mood, Joint & Liver Formulations
Product Overview: The Master Methyl Donor
Our S-Adenosylmethionine (SAMe) Powder represents the pinnacle of quality and stability in methyl donor supplements. Provided in its stable disulfate tosylate salt form with a guaranteed purity of 99%, this ingredient is essential for advanced formulations targeting mood, joint, and liver health. We have overcome SAMe's notorious instability challenges through advanced manufacturing and specialized packaging, delivering a product that maintains its potency for your B2B manufacturing needs.
Physicochemical Properties
| Property | Specification |
|---|---|
| Product name | Ademetionine 1,4-Butanedisulfonate |
| Common Name | S-Adenosylmethionine (SAMe) Stable Salt |
| Product appearance | White to off-white crystalline powder |
| Molecular formula | C<sub>15</sub>H<sub>23</sub>N<sub>6</sub>O<sub>5</sub>S • C<sub>4</sub>H<sub>8</sub>O<sub>6</sub>S<sub>2</sub> |
| Molecular weight | 562.63 g/mol |
| CAS NO | 101020-79-5 |
| Purity (HPLC) | ≥99% (as SAMe) |
| Melting point | Decomposes at ~180-185°C |
| Shelf life | 24 months (under recommended storage conditions) |
| Solubility | Freely soluble in water; sparingly soluble in ethanol |
| Optical rotation | [α]<sub>D</sub><sup>20</sup> +48° to +52° (c=1, 0.1N HCl) |
| Packaging | 1kg/aluminum foil bag with desiccant, 25kg/fiber drum |
| Storage | Store at 2-8°C in an airtight container. Protect from light and moisture. |
Key Health Benefits & Mechanisms of Action
SAMe is a crucial endogenous compound that plays multiple roles in human physiology, primarily through its function as the body's primary methyl group donor.
- Supports Emotional Well-being & Mood Balance: SAMe plays a fundamental role in the synthesis of key neurotransmitters, including serotonin, dopamine, and norepinephrine. Clinical research supports its use in maintaining emotional balance and supporting a positive mood state, making it a valuable ingredient for mood health formulations [1].
- Promotes Joint Comfort & Cartilage Health: SAMe contributes to the synthesis of proteoglycans, essential components of joint cartilage. Studies demonstrate its ability to support joint comfort, flexibility, and mobility, offering a well-researched natural approach to joint health maintenance [2].
- Enhances Liver Function & Detoxification: As the primary methyl donor in hepatic metabolism, SAMe supports crucial liver detoxification pathways and helps maintain healthy glutathione levels. This makes it an important ingredient for formulations designed to support liver health and overall detoxification processes.
- Cognitive Function & Cellular Protection: Through its role in methylation reactions and phospholipid synthesis, SAMe supports brain health and cognitive function while providing antioxidant protection at the cellular level.
Targeted Application Areas
This versatile ingredient serves multiple formulation needs:
- Mental Health Supplements: Mood support formulas, stress management products, and emotional wellness blends
- Joint Health Products: Arthritis support formulations, mobility supplements, and comprehensive joint care systems
- Liver Support Formulations: Detox supplements, liver health products, and metabolic support blends
- Anti-Aging & Wellness Products: Comprehensive health maintenance formulas and cognitive support supplements
Scientific Backing & Regulatory Compliance
The efficacy of our SAMe Powder is supported by substantial clinical evidence:
- A comprehensive review in the American Journal of Psychiatry confirmed SAMe's role in supporting emotional wellness [1].
- Research published in BMC Musculoskeletal Disorders demonstrated significant benefits for joint comfort and function [2].
All product information is intended for business-to-business ingredient sourcing. Final product manufacturers are responsible for ensuring compliance with local regulatory requirements for health claims and intended use.
Frequently Asked Questions (FAQ)
Q: Why is your SAMe in Ademetionine 1,4-Butanedisulfonate form?
A: This salt form provides superior stability, ensuring product potency and longer shelf life for your formulations.
Q: How is stability maintained during shipping?
A: We use specialized insulated packaging with moisture-proof bags to protect product integrity during transit.
Q: What documentation do you provide?
A: We provide Certificate of Analysis (COA) with purity verification, plus MSDS upon request.
Q: What's the minimum order quantity?
A: MOQ is 100g, with volume discounts available for larger orders.
Q: How should I handle SAMe during manufacturing?
A: Minimize exposure to heat, air and moisture. Use refrigerated storage and low-moisture processes.
Q: Where can I find research on SAMe benefits?
A: Refer to PubMed and the scientific references listed on our product page.
OME service
Packaging & Shipping
Certification
How To Contact Us?
If you are interested in this product and would like to learn more, you can contact our account manager through our international website or via email. Our email address is ella.zhang@huilinbio-tech.com.
References
[1] Sharma, A., Gerbarg, P., Bottiglieri, T., Massoumi, L., Carpenter, L. L., Lavretsky, H., Muskin, P. R., Brown, R. P., & Mischoulon, D. (2017). S-Adenosylmethionine (SAMe) for Neuropsychiatric Disorders: A Clinician-Oriented Review of Research. The Journal of Clinical Psychiatry, 78(6), e656–e667. https://doi.org/10.4088/JCP.16r11113
[2] Najm, W. I., Reinsch, S., Hoehler, F., Tobis, J. S., & Harvey, P. W. (2004). S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. BMC Musculoskeletal Disorders, 5, 6. https://doi.org/10.1186/1471-2474-5-6
Hot Tags: s-adenosylmethionine (same) powder, China, suppliers, manufacturers, factory, wholesale, buy, price, bulk, pure, natural, high quality, in stock, for sale, Supplement Ingredients, 99 L arginine Powder, Methyl Sulfonyl Methane Powder, L lysine HCL Powder
