Basic information on Laurocapram azone powder
Laurocapram azone powder, referred to as azone and lauroazone for short, is a highly efficient and safe penetration enhancer. Its chemical name is 1-n-dodecylazepan-2-one, it is a white crystalline powder, the product can be dissolved in organic solvents such as ethanol, propanol, chloroform, etc., and it has no effect on the skin Irritant, so it is a relatively safe substance.
Azone is a non-polar lipophilic and hydrophilic drug penetration enhancer. It can soften the stratum corneum, enhance the permeability of the skin, and enable the drug to better penetrate the skin barrier and be absorbed by the body. At the same time, it can also enhance the efficacy of drugs and reduce the use of drugs, thereby significantly reducing costs. And it is a new, efficient, safe, and non-toxic substance so that it can be used with confidence.
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INCI: |
Laurocapram |
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Chemical name: |
1-n-dodecylazepan-2-one |
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Chemical formula: |
C18H35NO |
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Molecular weight: |
281.477 |
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CAS accession number: |
59227-89-3 |
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EINECS Number: |
261-668-9 |
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Melting point: |
-7 ℃ |
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Density: |
0.9 g/cm³ |
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Flashpoint: |
165.2 ℃ |
Preparation of laurocapram powder
Selection of starting materials: Selecting suitable starting materials is the first step of synthesis. In general, the synthesis of azaleas may start with the corresponding ketones, amines or other nitrogen-containing compounds.
Construction of azeotrope: The construction of azeotrope is carried out through a specific synthetic route, such as condensation reaction with amide compounds. This step may involve the formation of Schiff base, followed by cyclization to obtain nitrogen heterocyclic structure.
Introduction of laurel group: the introduction of laurel group may be realized by many methods, such as esterification or amidation of lauric acid or its derivatives with aza-Zhuo ring. This step requires precise control of reaction conditions to ensure the successful introduction of laurel groups into the target site.
Purification: After synthesis, it is usually necessary to purify the product by column chromatography, recrystallization or distillation to remove unreacted starting materials, by-products and other impurities.
Drying and crushing: the purified azone needs to be dried to remove the solvent, and then the powder product is obtained by crushing.
Quality control: Finally, it is necessary to strictly control the quality of the synthesized laurocapram powder, including the determination of its purity, structural identification (such as NMR, IR, MS, etc.) and physical and chemical properties (such as melting point and solubility, etc.).
Application of Lauracene Powder
Drug synthesis: Azones are usually widely used in the medical field. They can be used as intermediates or active ingredients of antibacterial agents, anti-inflammatory drugs, analgesics and other drugs. If azone has specific biological activity, it may be used to develop new drugs or improve the synthesis process of existing drugs.
Agrochemicals: Some nitrogen compounds are used as plant growth regulators or pesticides in agriculture. If azone has related physiological activities, it may be used as a pesticide or growth regulator in agricultural production.
Organic synthesis: As an organic intermediate, laurocapram powder may play a key role in the synthesis of other organic compounds, for example, as a link in a multi-step synthesis reaction, or be transformed into more complex compounds through other reactions.
Materials Science: Azo compounds have potential applications in materials science because of their special electronic properties and stability, such as organic photoelectric materials, liquid crystal materials and organic semiconductors.
Analytical chemistry: If azone has specific spectral properties, it may be used as a standard or probe in analytical chemistry to detect, quantify or study other compounds.
Spices and essences: Some azaleas have unique fragrance. If azone belongs to this category, it may be used as a spice additive in food, cosmetics or perfume industries.
Biochemical research: Azo derivatives are sometimes used as inhibitors or substrate analogues of enzymes in biochemical research, through which specific biochemical pathways or enzyme catalytic mechanisms can be studied.
Application of Laurocapram Azone Powder in medicine field
Pharmacoactive molecules: Some azaleas derivatives have biological activity and can be used as antibacterial, antifungal, antiviral, anticancer or antihypertensive drugs. If azone has such biological activity, it may be directly used as a drug or as a precursor of active pharmaceutical ingredients.
Drug Intermediates: In the synthesis of complex drug molecules, azaleas can appear as intermediates and play a key role in multi-step synthesis. Lauracene may be used to synthesize more complex drug molecules, especially those containing azaleas.
Enzyme inhibitors: Azo compounds can sometimes inhibit specific enzymes, so they may be used to develop drugs to treat various metabolic diseases. If azone can interact with specific enzymes, it may be studied and utilized as an enzyme inhibitor.
Ligand or receptor mimics: Azo compounds can be used as mimics of some biomolecules to study cell signal transduction, the mechanism of action of neurotransmitters and so on. If azone has this property, it may be used in pharmacological research.
Reference standard: Pure compound standard is essential in drug analysis and quality control. If azone is a structural component of a drug, it can be used as a reference standard for the drug.
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Function of laurocapram powder in agriculture
Plant growth regulators: Some azaleas derivatives can affect the growth hormone level of plants, so they are used as regulators to promote or inhibit plant growth. If azone has such physiological activity, it may be developed as a plant growth regulator to control crop growth rate, improve fruit quality or increase yield.
Insecticides and fungicides: Some azaleas have antimicrobial activity and can be used as fungicides or pesticides. Lauracene may be used to control crop diseases and pests if it shows toxicity to specific pathogenic bacteria or pests.
Herbicide: Some members of azaleas are used as herbicides to control the growth of weeds and protect crops from competition. If azone has selective growth inhibition on specific plant species, it may be developed as a herbicide.
Seed treatment agent: Azo compounds may also be used for seed treatment to improve seed germination rate, enhance disease resistance or protect seeds from soil-borne diseases and pests. Lauracene can be used as a seed coating or treatment agent if it is safe and effective.
Soil improvers: In some cases, nitrogen compounds may be used as soil additives to help improve soil structure or regulate microbial communities in soil.
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Features of Laurea Azone
1. It has a strong penetration-promoting effect. The product can show a strong penetration effect at a low concentration of 0.5-2%.
2. It has a wide range of applicability, and has a robust penetration-promoting effect on a variety of hydrophilic and hydrophobic drugs.
3. It does not have any irritation to the skin and can be applied directly to the wound.
4. It is particularly convenient to use; add the substance to the drug solution and shake it into an emulsion before use.
5. It can reduce the use of drugs.
How to contact us?
Our company is a professional supplier of Laurocapram azone powder, with a variety of series of high-quality products, and these products are sold directly from the factory, so the price is relatively favorable, such as plant extracts, fruit and vegetable powder, cosmetics, tablet candy, etc. We have all products in stock.
At present, our company is selling the above products, and if you want to know the price of this product, you can consult us. Our contact information is: contact us through the international website or email, and our email is ella.zhang@huilinbio-tech.com; in addition, you can also contact us through the factory address, West Street, Yanta District, Xi'an City, Shaanxi Province Room 706, Building B, Fengze Science, and Technology Park, No. 170, come to see the factory on-site.







