Palmitoyl Tripeptide -5

Xi'an Huilin Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of palmitoyl tripeptide -5 in China. With abundant experience, we are committed to providing high quality natural products with competitive price. Please feel free to wholesale bulk pure palmitoyl tripeptide -5 for sale here from our factory.

Product Introduction

Palmitoyl tripeptide -5 is the earliest and most widely used cosmetic peptide in the peptide series. As the name implies, palmitoyl is linked to tripeptide, and grafting of palmitoyl is helpful to better enter the skin through biological barrier and lipid membrane (hydrophilic peptide segment and hydrophobic palmitoyl end, hydrophilic and lipophilic). It can promote the synthesis of collagen and elastin in dermis. Palmitoyl tripeptide -5 stimulates the synthesis of skin collagen through tissue growth factor (TGF-β), thus achieving the purpose of smoothing wrinkles and firming skin. Similar to traditional anti-wrinkle raw materials, such as derivatives of vitamin C and vitamin A. The research of P&G company shows that palmitoyl pentapeptide -3 can promote the production of collagen and other extracellular matrix proteins (including elastin and fibronectin, etc.), which is why it is widely used. In China, this kind of small-molecule cosmetic peptides are still in the primary and imitation stage, but small-molecule peptides with 3 or 4 amino acids are basically synthesized by solid-phase method, and the beauty industry can also borrow the synthetic technology of medicinal peptides.

Basic information

The role of palmitoyl tripeptide -5

Palmitoyl tripeptide -5, its cosmetic effect can be comparable to that of injecting collagen. It can promote the synthesis of collagen and glucosamine in human fibrous cells, strengthen connective tissue, increase skin firmness and promote cell activity; Inhibition of oxygen free radicals and hydroxyl free radicals promotes the synthesis of matrix proteins, especially collagen, and may also increase the production of elastin, hyaluronic acid, glycosaminoglycan and fibronectin. When added to cosmetics, it can supplement collagen for skin, improve its elasticity and significantly reduce facial wrinkles; Can increase skin moisture content, restore smoothness and firmness, improve skin color, and enhance luster and transparency; In addition, it also has the effect of moistening the lips. The action mode is similar to retinoic acid, but there is no side effect of retinoic acid, which increases the synthesis of collagen and interstitial hyaluronic acid (HA), makes fine lines disappear and makes skin firm.

Mechanism of palmitoyl tripeptide -5

Palmitoyl tripeptide -5 is the most widely used cosmetic small molecular peptide, which can promote the synthesis of collagen and elastin in dermis. Palmitoyl tripeptide -5 belongs to signal peptide. Studies have shown that these peptides can promote the synthesis of collagen (type I, type II and type IV) and the production of extracellular matrix proteins by increasing the activity of stromal cells, making the skin look younger and more elastic. Palmitoyl tripeptide -5 can promote the synthesis of collagen and elastin in dermis, and is an ideal raw material for accelerating collagen production and repairing wrinkles. Adding palmitoyl tripeptide -5 to cosmetics can help skin replenish collagen, improve facial elasticity and significantly reduce facial wrinkles. At the same time, it also has the characteristics of enhancing cell activity, increasing skin moisture content, enhancing skin luster and improving skin color.

Preparation technology of palmitoyl tripeptide -5

Protection of amino acids: First, it is necessary to choose appropriate amino acids to construct pentapeptide chains. These amino acids need to be protected to prevent unnecessary reactions during synthesis. Commonly used protecting groups include BOC(tert-butyloxycarbonyl) or Fmoc (9-fluoronymethoxycarbonyl).
Synthesis reaction: Next, the pentapeptide chain is synthesized by solid-phase synthesis or liquid-phase synthesis in the process of gradually adding amino acid monomers. In each step of the reaction, it is necessary to couple the corresponding amino acid monomer with the synthesized polypeptide chain. Activators (such as DIC, HATU, etc.) and bases (such as dimethylaminopyrrolidine) are usually used to promote the reaction.
Deprotection: After the synthesis of pentapeptide chain is completed, the protective group of amino acid needs to be removed to restore its free amino and carboxyl groups. This is usually achieved by treating chemical reagents such as trifluoroacetic acid or hydrochloric acid.Purification and analysis: After the synthesis of palmitoyl tripeptide -5, it is necessary to purify and analyze the product to remove impurities and ensure the purity and structure of the target product. This usually involves the use of column chromatography, high performance liquid chromatography and other techniques.

Detection method of palmitoyl tripeptide -5

High performance liquid chromatography (HPLC): This is a commonly used analytical technique, which can be used to detect and analyze the content and composition of chemical substances. Palmitoyl tripeptide -5 can be separated and detected by passing the sample through a column and using an appropriate solvent.
Mass Spectrometry: Mass spectrometry can provide detailed information about the structure and composition of compounds. By ionizing the compound in the sample and measuring its mass and relative abundance, it can be determined whether it contains palmitoyl tripeptide -5.
Spectroscopy: The existence of specific compounds in the sample can be determined by infrared spectroscopy or ultraviolet-visible spectroscopy. These techniques can identify palmitoyl tripeptide -5 according to the spectral characteristics of absorption or emission in the sample.
Enzyme-linked immunosorbent assay (ELISA): ELISA is a commonly used biochemical analysis method, which can be used to detect the presence of specific molecules. The presence of palmitoyl tripeptide -5 can be determined by reacting the sample with a specific antibody and then detecting it with an enzyme-labeled secondary antibody.
Nuclear Magnetic Resonance (NMR): NMR technology can provide detailed information about the molecular structure and composition in the sample. By analyzing the NMR spectrum of the sample, it can be determined whether it contains palmitoyl tripeptide -5.

OME service

Flow Chart

Packaging & Shipping

Our Certification

Contact information

Please contact us at ella.zhang@huilinbio-tech.com.

why choose us?

• We abide by all relevant industry standards and regulations to ensure the safety and quality of our products.
• We insist on innovation and learning to promote the transformation and upgrading of enterprises.
• We are a factory in China, providing high-quality Palmitoyl Tripeptide -5products and professional services. Companies adhering to the "integrity, dedication, innovation and development" concept, all staff unite as one.
• We attach importance to customer feedback and use it to continuously improve our products and services.
• Our factory is committed to providing quality products. We adopt strict quality control standards to ensure the purity of raw materials and the safety of products. We adopt advanced production technology and equipment to ensure the stability and consistency of products.
• Our products have been strictly tested and verified, and meet the international food hygiene standards.
• We have an experienced research team dedicated to the research and development of Palmitoyl Tripeptide -5. They cooperate with many scientific research institutions and universities to innovate and improve constantly to keep their products competitive in the market. We pay attention to the latest scientific research progress and technical trends to ensure the quality and effect of products.
• We provide customized services, and adjust the packaging, specifications and formula according to the needs of customers. We can provide personalized solutions and work closely with customers to ensure that our products meet their expectations and requirements.
• We have a good reputation and reputation. We are guided by customer satisfaction, adhering to the principle of honest management and service concept. Our team always treats customers with a professional, efficient and friendly attitude and answers their questions and needs on time.

Hot labels:Palmitoyl Tripeptide -5 , China, supplier, manufacturer, factory, wholesale, purchase, price, bulk, pure, natural, high quality, spot, for sale, chicory inulin, Coptis chinensis extract powder, apple extract powder, vegetable powder, copper peptide powder, hydrolyzed keratin powder.

Hot Tags: palmitoyl tripeptide -5, China, suppliers, manufacturers, factory, wholesale, buy, price, bulk, pure, natural, high quality, in stock, for sale, Vincamine Powder, Genistein Powder, Lipoic Acid Powder, Naringin Powder, Herb Extracts, Artemisinin Powder