Name: Indole-3-carbinol Powder
Brand: Huilin
SKU: 162131430

Product information

Indole -3- methanol powder is one of the hydrolysis products of glucosinolate, with chemical formula of C9H9NO, molecular weight of 147.18 and CAS number of 700-06-1. Indole -3- methanol is a gray powder with a melting point of 96 ~ 99℃, which is partially soluble in cold water. It is a natural compound and is often used in health food and medicine. It exists in some vegetables such as broccoli, cabbage and other cruciferous vegetables. Indole-3-methanol powder is a powdery substance extracted from indole-3-methanol. Indole -3- methanol powder is widely used in health care products, drugs, cosmetics and other fields because of its certain health care function. Common uses include improving the function of immune system and regulating endocrine.

Indole-3-carbinol sample display

Basic parameters

Melting point	96-99 °C(lit.)
Boiling point	267.28°C (rough estimate)
density	1.1135 (rough estimate)
refractive index	1.5670 (estimate)
storage temp.	2-8°C
PKA	15.10±0.10(Predicted)
form	Crystalline Powder or Flakes
color	Off-white to yellow-orange
BRN	121323
Stability:	2-80C
CAS DataBase Reference	700-06-1(CAS DataBase Reference)

Main sources and production preparation methods

Main source:

Indole -3- methanol, indole -3- methylthio grape colored flowers exist in cruciferous vegetables, such as Brussels sprouts, cabbage, cauliflower, turnip, cabbage and kale.
Production preparation method:

Indole-3-methanol has a simple structure and is convenient for chemical synthesis. Indole -3- methanol was synthesized from indole, phosphorus oxychloride and N,N- dimethylformamide by Vilsmeier-Haack reaction. Then, in toluene-water reaction system, potassium borohydride was used as reducing agent, and indole -3- methanol was obtained at 50 ~ 60℃. The reaction conditions were mild and the yield was 69.
Compounds such as indole -3- methylthio grapevine flower and 4-hydroxy-indole -3- methylthio grapevine flower also have plant extracts.

Physiological function and function

Antihormone-like activity:
Indole -3- methanol can increase the activity of cytochrome P4501A and affect the metabolic pathway of estrogen, increase the activity of estradiol 2- hydroxylase and the metabolic level of catechol pathway, thus increasing the level of 2- hydroxy-estrone. Indole -3- methanol can also reduce the stimulation of female glands by reducing the 16α- hydroxyestrogen pathway, exert anti-hormone-like activity and inhibit some estrogen-dependent tumors.
Inhibition of DNA binding:
Indole -3- methanol can prevent aflatoxin AFB1 from binding to DNA and inhibit the induced mutation of AFB1 on organisms.
Regulating metabolic enzyme activity in vivo;
Indole -3- methanol can induce the activities of drug metabolizing enzymes in PhaseⅠ and PhaseⅡ, increase the activities of glutathione S transferase (GST), epoxide hydrolase and quinone oxidoreductase NAD(P)H in tissues and target organs, participate in detoxification of electrophiles and protect cells from oxidative damage.

Benefits of Indole -3- methanol Powder

Beneficial to women's health: Indole -3- methanol powder is very beneficial to women, it can help women regulate endocrine and relieve menstrual pain, and it can also help women excrete excess estrogen, which is very beneficial to women's health.
Enhance human immunity: improve human resistance and prevent infections and diseases.
Lowering blood sugar: it has a certain auxiliary therapeutic effect on diabetic patients.
Reducing blood lipid: reducing the occurrence of cardiovascular diseases. In addition, it can protect liver by promoting the metabolism of liver cells.

Use of indole -3- methanol powder

1. Medicine
Indole -3- methanol powder is an important raw material for manufacturing many medicines, and it can be used as an intermediate for synthesizing anticancer drugs, antibiotics and antiviral drugs. For example, many drugs such as cefalexin, streptomycin and quinolones need indole -3- methanol.
2. Dyes
Indole -3- methanol can be used as the raw material of dyes, and it can be made into dyes with different colors such as blue and purple, which are widely used in textile, printing and dyeing fields.
3. Pesticides
Indole -3- methanol powder can also be used to make pesticides, and can be used as an intermediate for synthesizing pesticides and herbicides, so as to improve crop yield.
4. Photoelectronic materials
Indole -3- methanol powder can also be used to manufacture semiconductor photoelectric devices. It has the characteristics of photoluminescence, single crystal and luminous stability, and can be used to manufacture optoelectronic materials, such as LED.

Applied in the medical and healthcare industry

Common usage and recommended intake

1. Common usage methods
(1) The food indole -3- methanol exists in cruciferous vegetables.
(2) Health food can be used in health food.
2. Recommended intake
It is suggested that the daily dosage of indole-3-methanol is 300 ~ 400 mg. I3CTM capsules are used as dietary supplements for cervical atypical hyperplasia. Each capsule contains 100mg of edible indole-3-methanol, which is taken orally for 200mg or 400mg every day.

Why choose us?

We are constantly innovating and developing new and exciting Natural Ingredients.
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As a supplier and manufacturer, we pride ourselves on providing excellent service and products.
We have the world's leading level of research and development, testing and production instruments and equipment, and the use of international advanced quality testing means and quality assurance system.
Our team is dedicated to producing Natural Ingredients of the highest quality.
Our company adheres to the business principle of 'seeking truth, being pragmatic, efficient and dedication', and strict quality assurance system. In the new century, we will follow the tenet of 'innovation, enterprising, rigorous and pragmatic', and the enterprise spirit of 'excellent quality and excellence' and high-quality service, which will help your enterprise take off.
Our Natural Ingredients are made using the latest equipment and techniques.
With the development of the market and the increasing level of demand, we are fully aware of the importance and urgency of new Indole-3-carbinol Powder development.

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