Product Information
Cornus Officinalis Extract Powder, derived from the fruit of the Asiatic Dogwood (Cornus officinalis, known as Shan Zhu Yu in Traditional Chinese Medicine), is a premium botanical ingredient with a 2,000-year history of use. This extract is a concentrated source of potent bioactive compounds, primarily iridoid glycosides (like morroniside and loganin), flavonoids, and polyphenols. Traditionally revered for its "liver and kidney nourishing" properties, modern scientific research now validates its broad spectrum of pharmacological activities. Our extract is produced under strict quality control from select mature fruit pulp, ensuring optimal potency and consistency for use in nutraceutical, cosmetic, and functional food products.
Basic Parameters
| Parameter | Specification | Details / Method |
|---|---|---|
| Source Plant | Cornus officinalis Sieb. et Zucc. | Authenticated Asiatic Dogwood. |
| Part Used | Dried Fruit Pulp (de-seeded) | Mature, fully ripe fruit. |
| Appearance | Brown-yellow fine powder | Homogeneous, free-flowing. |
| Active Standardization | Loganin 7%, 10%, 20% (or custom) | Quantified by HPLC. Morroniside content also available. |
| Mesh Size | 80-100 Mesh | Ensures good solubility and mixability. |
| Solubility | Soluble in water and ethanol-water solutions | Suitable for various delivery systems. |
| Heavy Metals | Complies with major pharmacopoeia limits | As per USP/EP/ChP standards. |
| Microbiological Limits | Complies with standard requirements | Total plate count, yeast/mold, pathogens. |
| Residual Solvents | Meets ICH guidelines | For solvent-extracted products. |
Mechanism of Action
The multifaceted benefits of Cornus Officinalis Extract stem from the synergistic action of its key bioactive compounds, primarily targeting oxidative stress, inflammation, and key cellular enzymes.
- Potent Antioxidant & Anti-inflammatory Activity: The extract's rich profile of iridoids (loganin, morroniside, cornuside) and polyphenols directly scavenges free radicals and upregulates endogenous antioxidant defenses (e.g., via the Nrf2 pathway). It inhibits the production of pro-inflammatory cytokines (like TNF-α and IL-6) by modulating key signaling pathways such as NF-κB, thereby reducing chronic, low-grade inflammation linked to aging and metabolic disorders.
- Metabolic & Organ-Protective Effects: Iridoid glycosides are central to its traditional benefits. Research shows morroniside and loganin help protect kidney cells from high glucose-induced damage and inflammation, supporting renal health. They also demonstrate protective effects on liver cells and neurons by mitigating oxidative stress and apoptosis.
- Skin-Specific Bioactivity:
Tyrosinase Inhibition: Cornuside, a specific secoiridoid, has been shown to effectively inhibit tyrosinase, the key enzyme in melanin synthesis, providing a mechanism for skin brightening and reducing hyperpigmentation.
Anti-Photoaging: Studies indicate the extract can ameliorate UVB-induced oxidative damage in skin models, protecting collagen and elastin.
Elastase Inhibition: Compounds like ursolic acid from the seeds (often present in whole-fruit extracts) inhibit elastase, an enzyme that breaks down skin elastin, thereby helping to maintain skin firmness and reduce wrinkles.
Primary Benefits & Applications of Cornus Extract Powder
A) Nutraceutical & Pharmaceutical Applications:
Kidney & Liver Health Support: A cornerstone of TCM, the extract is used in famous formulas like Liuwei Dihuang Wan and Hachi-Mi-Ji-O-Gan (Ba-Wei-Di-Huang-Wan) to support renal and hepatic function, addressing issues like frequent urination, tinnitus, and dizziness. Modern studies confirm its renoprotective and hepatoprotective effects.
Blood Sugar Metabolism: Exhibits anti-diabetic potential by improving insulin sensitivity and inhibiting intestinal α-glucosidase, which can help moderate post-meal blood glucose spikes.
Neuroprotection & Cognitive Support: Components like morroniside protect neuronal cells from oxidative damage and may support memory, aligning with its use in traditional Korean formulas for brain function.
Cardiovascular Wellness: Its antioxidant and anti-inflammatory actions contribute to vascular health and may support healthy blood pressure.
B) Cosmetic & Skincare Applications (Cornus Officinalis Fruit Extract Skin Benefits):
Anti-Aging & Wrinkle Reduction: Combats oxidative stress and inhibits collagen/elastin degradation (via elastase inhibition), promoting firmer, more youthful skin.
Skin Brightening & Tone Correction: Through tyrosinase inhibition by cornuside, it helps reduce the appearance of dark spots, melasma, and overall hyperpigmentation.
Anti-Inflammatory & Soothing: Calms skin irritation, redness, and sensitivity, making it suitable for reactive or acne-prone skin.
Antioxidant Protection: Shields skin cells from environmental aggressors (pollution, UV) that cause premature aging.
C) Functional Food & Beverage Applications:
Health Drinks & Teas: Can be incorporated into herbal teas, tonics, and functional beverages for immune and energy support.
Dietary Supplements: Ideal for capsules, tablets, or powdered supplement blends targeting overall vitality, eye health, and antioxidant defense.
Natural Food Additive: Provides bioactive value to health-focused food products.
Formulation Guidelines
- Recommended Usage Levels:
Dietary Supplements: 50-300 mg per day of extract (standardized to ≥7% loganin).
Skincare Products: 1-5% concentration in the final formulation.
Functional Foods/Beverages: 0.1-1.0% concentration, subject to regulatory approvals.
- Solubility & Compatibility: Water-soluble. Can be incorporated into the aqueous phase of formulations. Compatible with most cosmetic emulsifiers and nutraceutical excipients.
- Stability: Stable under normal processing conditions. For long-term stability in finished products, protect from extreme heat, light, and moisture.
- Synergistic Combinations:
With Other Botanicals: Combines well with Lycium Berry (Goji) and Rehmannia in traditional kidney-support formulas. For skin, pairs with Licorice Root or Vitamin C for enhanced brightening.
With Vitamins: Potentiates the effects of antioxidants like Vitamin E and Vitamin C.
Frequently Asked Questions (FAQ)
Q: What is the difference between Cornus officinalis, Cornus mas, and Cornus kousa extracts?
A: Cornus officinalis (Asiatic/Japanese dogwood, Shan Zhu Yu) is the primary species used in TCM with extensive research on its medicinal iridoids. Cornus mas (Cornelian cherry) is a European species prized for its fruit and also contains beneficial compounds, but its traditional use and phytochemical profile differ. Cornus kousa (Kousa dogwood) is less commonly used medicinally. Ensure you source the correct species for your application.
Q: Is Cornus Officinalis Extract safe? Are there side effects?
A: It has a long history of safe use in traditional medicine. Modern acute toxicity studies show very low toxicity, with LD₅₀ values >10 g/kg in animal models. As with any potent botanical, it should be used at recommended levels. Consult a healthcare professional before use if pregnant, nursing, on medication, or with a known medical condition.
Q: How do I choose the right specification (e.g., 10:1 vs. 10% Loganin)?
A: The extract ratio (10:1) indicates concentration but not a specific active content. Standardized extracts (e.g., 10% Loganin) guarantee a quantified amount of key bioactive markers, ensuring consistent efficacy and are preferred for pharmaceutical and high-grade nutraceutical applications. The choice depends on your formulation goals and regulatory requirements.
Q: What are the key quality markers (Q-markers) for this extract?
A: According to pharmacopoeias and recent research, the most important Q-markers are loganin and morroniside. Advanced studies also identify loganic acid, cornuside I, and pelargonidin-3-O-glucoside as significant markers correlating with antioxidant activity and quality.
Q: Is Cornus Officinalis Fruit Extract comedogenic (pore-clogging)?
A: There is no evidence to suggest the purified, water-soluble extract powder is comedogenic. Its anti-inflammatory properties may be beneficial for some acne-prone skin types. However, final product formulation determines comedogenicity.
Process Flow
Selected materials → crushing (material coarse powder) → alcohol extraction → reduced pressure recovery of ethanol-water dilution and centrifugation → chromatographic extraction → water elution → ethanol elution → recovery of ethanol → spray drying → finished product inspection → packaging and storage
Package
The product is in bulk form, according to the quantity ordered by the customer, a reasonable packaging method is applied
Aluminum foil bags, thick cardboard boxes, cardboard drums, all inside are sealed with double-layer PE bags, moisture-proof and anti-collision packaging
Form: 1-25kg/aluminum foil bag, cardboard box, 25kg/cardboard drum
Logistics information
The logistics adopt small cargo express, large cargo air or sea transportation (depending on the number of purchases and customer requirements)
Logistics provider: DHL/FEDEX/TNT/EMS/UPS, etc.
Product Advantages
The product has good stability
Factory-direct sales, price concessions
High purity and quality guaranteed
Why Choose Us?
The company's customers cover the Nordic markets such as the United States and Canada, South America such as Chile and Brazil, and many European Union countries such as Germany, Spain, France, and the Netherlands.
The professional team of colleges and universities provides you with a full range of services from quality inspection, logistics, pre-sales and after-sales
Strictly control raw materials, production meets GMP standards, and quality control is tested by our own laboratory and authorized tripartite laboratories
Can provide customized services (product packaging, finished product forms such as powder, granules, tablets, capsules)
Contact Us
Elevate your next-generation health, beauty, or wellness product with the proven, multi-target benefits of premium-grade Cornus Officinalis Extract. Contact our technical sales team today to:
- Request a FREE sample and comprehensive Certificate of Analysis (COA).
- Discuss custom specifications (Loganin 7%, 10%, 20% or other actives).
- Get competitive bulk pricing.
Please contact us by email: ella.zhang@huilinbio-tech.com
Why choose us?
- Our Herbal Extracts are customizable to meet the specific formulation requirements of our customers.
- Since its establishment, our company has actively participated in relevant international technical exchanges, and has close technical cooperation with relevant domestic universities.
- Our Herbal Extracts are free of contaminants and meet the highest quality standards.
- Future-proof factories are automated to increase efficiency and equipped with enterprise resource planning (ERP) systems and advanced monitoring and data acquisition systems to support operations.
- As a professional supplier and manufacturer, we are committed to providing our customers with the best quality products.
- We will provide customers with electronic catalogs including different types and specifications, and we will introduce our products in detail.
- Our team of experts ensures that all of our Herbal Extracts are of the highest quality.
- We insist on people-oriented, because people are the main body of the enterprise and the most active factor in productivity.
- We provide personalized solutions to meet the specific needs of our customers.
- We prolong the value of our corporate brand by increasing the value of our corporate Cornus Extract Powder so as to make our corporate foundation everlasting.
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