5-HTP Powder

5-HTP Powder

Product Name: Product Name: 5-HTP (5-Hydroxytryptophan)
Alias: Oxitriptan, L-5-HTP
Chemical name: (S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid
Source: Natural fermentation (from Griffonia simplicifolia seed extract)
Part Used: Seed
CAS no.: 4350-09-8
Purity: 98% (HPLC)
Appearance: White to off-white crystalline powder
Grade: Nutraceutical Grade, Pharmaceutical Grade
Application: Dietary supplements, mood support formulations, sleep aid products, weight management supplements
Minimum order quantity: 1kg
Sample: Available
Supplier: Xi'an Huilin Biological Technology Co., LTD
Looking for technical 5-HTP formulations? Contact us for custom solutions and COA.

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Product Introduction

5-HTP (5-Hydroxytryptophan) 98% | Advanced Serotonin Precursor with Enhanced Bioavailability for Mood & Sleep Formulations

 

Product Overview: Precision Neuroscience Ingredient

 

Our pharmaceutical-grade 5-HTP (5-Hydroxytryptophan) represents the optimal choice for serotonin support formulations. With guaranteed ≥98% purity and advanced delivery system compatibility, this ingredient provides formulators with a scientifically-validated solution for mood, sleep, and neurological health applications.

 

Product Specification

 

Parameter Specification
Product Name 5-HTP (5-Hydroxytryptophan)
CAS Number 4350-09-8
Purity (HPLC) ≥98%
Appearance White to off-white crystalline powder
Molecular Formula C11H12N2O3
Molecular Weight 220.23 g/mol
Mesh Size 100% through 80 mesh
Loss on Drying ≤0.5%
Heavy Metals ≤10 ppm
Residual Solvents Meets ICH guidelines
Microbiological Total Plate Count ≤1000 CFU/g
Storage 2-8°C in airtight container, protect from light

 

Key Health Benefits & Clinical Applications

 

1. Comprehensive Mood Support System
5-HTP's direct conversion to serotonin makes it particularly valuable for mood support formulations. Clinical research shows significant benefits for emotional well-being, with effects comparable to conventional antidepressants in some studies [1].

 

2. Sleep-Wake Cycle Regulation
Through the serotonin-melatonin pathway, 5-HTP supports healthy sleep architecture. Recent studies demonstrate improved sleep quality and reduced sleep latency, particularly in sustained-release formulations.

 

3. Fibromyalgia & Chronic Pain Support
Substantial clinical evidence supports 5-HTP's efficacy in fibromyalgia management. Research shows significant improvement in pain, morning stiffness, and anxiety symptoms [2].

 

4. Appetite Regulation & Metabolic Health
5-HTP promotes satiety through serotonin-mediated mechanisms, supporting healthy weight management when combined with lifestyle modifications.

 

7

Scientific Differentiation: 5-HTP vs. Tryptophan

 

Metabolic Pathway Advantage:
Tryptophan → (Rate-Limited Step) → 5-HTP → Serotonin → Melatonin

 

Unlike L-tryptophan, which competes with other amino acids for transport and faces a rate-limiting conversion step, 5-HTP offers distinct advantages:

  • Direct Conversion: Bypasses the rate-limiting tryptophan hydroxylase step
  • Superior Blood-Brain Barrier Penetration: Independent of competing amino acids
  • Enhanced Efficacy: Demonstrated superior bioavailability in clinical settings

 

Synergistic Formulation Approaches

 

  • Sleep Support: 5-HTP + GABA + Magnesium Glycinate + Vitamin B6
  • Mood Enhancement: 5-HTP + SAMe + Rhodiola Rosea + Methyl B12
  • Weight Management: 5-HTP + Green Tea Extract + Chromium
  • Neurological Support: 5-HTP + Acetyl-L-Carnitine + CoQ10

 

Related product introduction

 

Product Name

CAS

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CAS

Xylazine HCl

23076-35-9

5-htp

4350-09-8

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5413-05-8

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105-41-9

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1094-61-7

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30123-17-2

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99-92-3

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22374-89-6

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236117-38-7

Beta-methyl-phenethylamine hydrochloride

20388-87-8

2-Bromo-4-methylpropiophenone

145-82-7

   

 

Certificate of Analysis

 

Item

Standard

Test Result

Assay(5-Hydroxytryptophan)

≥98.0%(HPLC)

99.20%

Organoleptic

   

Appearance

Fine Powder

Conforms

Color

Off White

Conforms

Odor

Characteristic

Conforms

Taste

Characteristic

Conforms

Physical Characteristics

   

Moisture Content

≤5.0%

0.46%

Heavy metals

   

Total Heavy Metals

≤10.0ppm

Conforms

Lead(Pb)

≤3.0ppm

Conforms

Arsenic(As)

≤2.0ppm

Conforms

Mercury(Hg)

≤0.1ppm

Conforms

Cadmium(Cd)

≤1.0ppm

Conforms

Microbiological Tests

   

Total plate Count

≤10000cfu/g

180cfu/g

Yeast & Mold

≤100cfu/g

Conforms

E.Coli.

≤30cfu/g

Conforms

Salmonella

Negative in 25 g

Not Detected

Staphylococcus Aureus

Negative in 25 g

Not Detected

Conclusion

Conforms to the In house standard.

 

 

Customized Service

 

OEM&ODM

Product packaging introduction

 

Quantity

Packaging

1-3kg

1-3kg/aluminum foil bag with food-grade plastic bag inside.

4-25kg

4-25kg/carton with double food-grade plastic bag inside.

≥25kg

25kg/drum or carton with double food-grade plastic bag inside.

Delivery time

Usually within 3-5 working days after receiving the payment.

Packing of Tranexamic Acid

Shipping & Delivery

 

Express(DHL/TNT/FEDEX)

By Air

By Sea

1-50kg

50-500kgs

Above 500kgs

Fast and convenient

Fast and cheap

Cheap and long time

4-8 days

4-8 days

15-45 days

Door to door

To airport

To port

Shipping & Delivery1

FAQ

 

What is the main market for your company's business?

We are determined to provide high-quality products to the world.

 

Is your delivery date fast?

We cooperate with many logistics companies and have a complete supply chain system. Shipments can be made within 3-5 days.

 

How do you make packaging products?

We use aluminum foil bags, cartons, barrels, and other methods to ensure that customers receive products safely.

 

How do you collect money?

We provide Western Union and L/C, T/T, Trade Assurance, and other methods, or negotiate according to customer requirements.

 

Do you have samples to send?

We are willing to provide customers with free samples for quality testing, you only need to bear the freight.

 

How to contact us?

 

Our company is a professional supplier of semi-finished materials, including plant extracts, fruit and vegetable powder, cosmetics, tablet candy, and other products; Our products are directly supplied from the manufacturer, so the price is very favorable, and the quality is guaranteed so that you can buy with confidence.

Now our company is hot-selling high-quality 5-htp powder, if you are interested in this product and want to know about it, you can consult our account manager through the international website or email. Our email address is ella.zhang@huilinbio-tech.com.

 

References

 

[1] Shaw, K. A., Turner, J., & Del Mar, C. (2002). Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database of Systematic Reviews, (1), CD003198. https://pubmed.ncbi.nlm.nih.gov/11869656/

[2] Caruso, I., Sarzi Puttini, P., Cazzola, M., & Azzolini, V. (1990). Double-blind study of 5-hydroxytryptophan versus placebo in the treatment of primary fibromyalgia syndrome. The Journal of International Medical Research, 18(3), 201–209.  https://journals.sagepub.com/doi/10.1177/030006059001800304

[3] Turner, E. H., et al. (2006). Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan. Pharmacology & Therapeutics, 109(3), 325-338. https://pubmed.ncbi.nlm.nih.gov/16023217/

 

Regulatory Compliance & Safety Notice:
This product is intended for use as a dietary ingredient by qualified manufacturers. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Important Contraindications: Do not use with SSRIs, MAOIs, or other serotonergic drugs. Not recommended during pregnancy or lactation. Always consult with a healthcare professional before use. Manufacturers must include appropriate warning labels and usage instructions.

 

Why choose us?

  • We provide a wide range of products to meet the diverse needs of our customers.
  • We are uniquely positioned to push the envelope and improve automation to move the world forward.
  • Our processes are designed to ensure that our Herbal Extracts are produced in a safe and hygienic environment.
  • Continue to strengthen lean management in the company's internal operations and continuously improve operational efficiency.
  • Our factory is equipped with modern logistics systems to ensure speedy and accurate deliveries.
  • In addition to the quality of our 5-HTP Powder, our excellent marketing team has also played a great role.
  • Our Herbal Extracts are free of contaminants and meet the highest quality standards.
  • We are open, frank and professional. We are responsible for the commitments and actions we make and abide by the highest ethical standards.
  • Our team of experts ensures that all of our Herbal Extracts are of the highest quality.
  • The growth of our company is inseparable from the trust, care and support from all walks of life, which are the greatest motivation for us to rise to the challenge and the confidence to achieve our business.

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