Name: China High Quality Alpha-ketoglutarate Calcium Manufacturers Suppliers - Factory Direct Wholesale - HUILIN BIO
Brand: Huilin Bio
SKU: 254941766

Xi'an Huilin Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of alpha-ketoglutarate calcium in China. With abundant experience, we are committed to providing high quality natural products with competitive price. Please feel free to wholesale bulk pure alpha-ketoglutarate calcium for sale here from our factory.

Product introduction

Alpha-Ketoglutarate Calcium (also known as Calcium AKG, Ca-AKG, or Calcium 2-oxoglutarate) is a high-purity, white to off-white powder that combines the essential metabolic intermediate α-ketoglutarate with calcium. With a molecular formula of C₅H₈CaO₅ and a specification of 98%, this compound serves as a pivotal ingredient in the tricarboxylic acid (TCA) cycle, playing a fundamental role in cellular energy production, amino acid metabolism, and protein synthesis. As a versatile calcium alpha-ketoglutarate supplement raw material, it is widely applicable in dietary supplements, functional foods, pharmaceuticals, and advanced cosmetic formulations.

Alpha-Ketoglutarate Calcium Powder

Basic information

Item	Specification
Product Name	Alpha-Ketoglutarate Calcium (Calcium AKG)
CAS No.	71686-01-6
Molecular Formula	C₅H₈CaO₅
Molecular Weight	184.160
Purity	98%
Appearance	White to Off-White Fine Powder
Particle Size	100% through 80 mesh sieve
Solubility	Soluble in Water
Grade	Pharmaceutical / Food / Cosmetic Grade
Shelf Life	24 months under proper storage
Storage	Keep in a sealed, cool, dry, and well-ventilated place.
Minimum Order Quantity (MOQ)	1 kg
Shelf life	2 years

molecular structure of Calcium AKG

Mechanism of Action and Core Benefits

The primary calcium alpha ketoglutarate benefits stem from its dual role as a key metabolic fuel and a calcium source.

Enhances Cellular Energy Metabolism: As a central intermediate in the TCA cycle, AKG is crucial for ATP (energy) production. Supplementation with calcium alpha-ketoglutarate powder may help support mitochondrial function, enhance cellular energy levels, and potentially reduce exercise-induced fatigue.
Supports Protein Synthesis & Muscle Health: AKG is a direct precursor to glutamine and glutamate, amino acids vital for muscle protein synthesis and nitrogen balance. This makes it a compound of interest for supporting muscle maintenance, recovery, and overall athletic performance.
Promotes Bone Health: The compound provides bioavailable calcium alongside AKG. Some research suggests that AKG itself may play a role in collagen synthesis and bone metabolism, offering a dual-action approach to supporting skeletal strength.
Exhibits Antioxidant Properties: AKG can participate in antioxidant pathways within cells, helping to neutralize free radicals and mitigate oxidative stress, which is associated with aging and various health concerns.
May Support Healthy Aging: Emerging research in model organisms has explored the potential of calcium alpha-ketoglutarate (ca-akg) supplement in influencing metabolic pathways linked to longevity and age-related decline, making it a subject of significant scientific interest in the healthspan field.

Primary Application Fields

Dietary Supplements & Nutraceuticals: Used as a core ingredient in capsules, tablets, and powdered blends targeting energy enhancement, sports nutrition, muscle support, metabolic health, and healthy aging formulations.
Functional Foods & Beverages: Incorporated into health drinks, protein powders, and fortified foods as a functional nutrient to boost the metabolic and nutritional profile of the product.
Pharmaceutical Intermediates: Serves as a high-purity raw material for the synthesis of more complex pharmaceutical compounds and in specialized clinical nutrition.
Cosmetic & Skincare Ingredients: Utilized in advanced skincare formulations for its potential calcium alpha ketoglutarate benefits related to antioxidant protection, supporting skin cell energy metabolism, and promoting a healthy skin appearance.

Safflower Extract Powder 2

Recommended Usage & Safety Information

Typical Dosage Range: In finished dietary supplements, common dosages for calcium alpha ketoglutarate supplement range from 500 mg to 2000 mg per day, often divided into two doses. The optimal dosage depends on the intended application and formulation.
Incorporation Method: This water-soluble powder can be easily mixed into the water phase during the manufacturing of beverages, foods, or cosmetic emulsions. For solid supplements, it blends well with other excipients.
Safety Profile: Alpha-ketoglutarate calcium is generally well-tolerated. Reported calcium alpha ketoglutarate side effects are rare and typically mild, such as occasional gastrointestinal discomfort at very high doses. As with any supplement, it is recommended to consult a healthcare professional before use, especially for individuals with kidney conditions or those taking medication.
Note on Forms: The product described here is calcium alpha ketoglutarate (anhydrous). The calcium alpha ketoglutarate monohydrate form (with one water molecule) has a different CAS number and slightly altered properties.

Company Profile

Xi 'an Huilin Biological Technology Co., Ltd. is a professional plant extract research and development, production and export of modern new enterprises, with nearly ten years of export experience, perfect testing equipment and professional testing personnel, to provide customers with high-quality products. The company's main products are food raw materials, health care raw materials, cosmetics raw materials and pharmaceutical raw materials. We have established good cooperative relations with most countries in the world.