Xi'an Huilin Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of palmitoyl tripeptide-1 & tetrapeptide-7 complex in China. With abundant experience, we are committed to providing high quality natural products with competitive price. Please feel free to wholesale bulk pure palmitoyl tripeptide-1 & tetrapeptide-7 complex for sale here from our factory.
Overview – At a Glance
Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7 Complex is a dual-peptide cosmetic active - not a single ingredient, but a two-peptide system combining two biomimetic signal peptides:
- Palmitoyl Tripeptide-1 (Pal-GHK) – a palmitoylated fragment derived from type I collagen
- Palmitoyl Tetrapeptide-7 (Pal-GQPR) – a signalling peptide widely used in skin-comfort and firming concepts
Both belong to the matrikine-type signal peptides - short peptide fragments derived from extracellular matrix proteins. Matrikines occur naturally in the skin: when structural proteins break down, the resulting fragments act as messengers that skin cells respond to. Cosmetic peptides based on this principle are designed to support the skin's natural renewal processes, helping to maintain a firm, smooth and comfortable-looking complexion.
The complex is typically supplied as a 1:1 lipidated peptide blend dissolved in a glycerin-water-butylene glycol carrier matrix (INCI: Glycerin (and) Aqua (and) Butylene Glycol (and) Carbomer (and) Polysorbate 20 (and) Palmitoyl Tripeptide-1 (and) Palmitoyl Tetrapeptide-7). It is fully water-soluble and stable across the cosmetic pH range, with optimal stability between pH 5 and 7.
Our Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7 Complex is manufactured through advanced Solid-Phase Peptide Synthesis (SPPS) followed by N-terminal palmitoylation and rigorous HPLC purification, ensuring consistent batch-to-batch quality and reliable performance in formulation.
Key Features & Advantages
- Dual-Peptide Signal Complex – Combines two biomimetic matrikines (Pal-GHK and Pal-GQPR) for complementary anti-aging action.
- Collagen Support – Designed to support the skin's natural collagen, complementing the appearance of firmness and smoothness.
- Skin Comfort Support – Palmitoyl Tetrapeptide-7 is widely used in formulas positioned around skin comfort and a calm-looking complexion.
- Enhanced Compatibility – The palmitoyl (lipid) chains increase lipophilicity and affinity with lipid-rich systems, supporting easy incorporation.
- Supports the Look of Deep Wrinkles – A well-established choice in formulas targeting the appearance of deep wrinkles and loss of firmness.
- Excellent Formulation Compatibility – Fully water-soluble; stable across pH 4.0 – 7.5; suitable for aqueous, emulsion and anhydrous systems.
- Gentle Profile – Designed to be well tolerated; commonly used in formulas developed for skin that prefers a gentle, retinol-free approach.
- Synthetic & Animal-Free – 100% synthetic production via SPPS; vegan and cruelty-free.
- Regulatory Documentation – Listed in CosIng, the PCPC INCI dictionary and China's Inventory of Used Cosmetic Ingredients (IECIC); supplied with a complete technical file for your compliance review. Intended for cosmetic use only.
- Versatile Grades – Standard 100 ppm liquid, 500 ppm concentrated liquid and freeze-dried powder.
Technical Specifications (Typical – Standard Liquid Grade)
| Parameter | Specification | Test Method |
|---|---|---|
| Product Name | Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7 Complex | – |
| INCI Name | Glycerin (and) Aqua (and) Butylene Glycol (and) Carbomer (and) Polysorbate 20 (and) Palmitoyl Tripeptide-1 (and) Palmitoyl Tetrapeptide-7 | – |
| CAS No. (Tripeptide-1) | 147732-56-7 | – |
| CAS No. (Tetrapeptide-7) | 221227-05-0 | – |
| Appearance | Clear to pale yellow viscous liquid | Visual |
| Palmitoyl Tripeptide-1 Content | 90 – 110 ppm | HPLC |
| Palmitoyl Tetrapeptide-7 Content | 45 – 55 ppm | HPLC |
| Peptide Ratio | 1:1 (mass ratio) | HPLC |
| Solubility | Fully water-soluble | – |
| pH Range | 3.0 – 9.0 (stable pH 4.0 – 7.5; optimal pH 5.0 – 7.0) | – |
| Heavy Metals | Compliant with cosmetic standards | ICP-MS |
| Total Plate Count | ≤100 CFU/g | USP <61> |
| Yeast & Mold | ≤10 CFU/g | USP <2021> |
| E. coli | Negative | USP <2022> |
| Salmonella | Negative | USP <2022> |
Specifications are for reference. Please request the current COA for batch‑specific data.
Key Skin Benefits
Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7 Complex is one of the most widely used dual-peptide systems in anti-aging skincare. Here are the key highlights:
1. Supports the Look of Firmer, Smoother Skin
- A signal peptide complex widely used in formulas designed to support the skin's natural renewal processes.
- Helps maintain a firm, smooth-looking complexion as part of a daily routine.
- A popular choice for products positioned around loss of firmness.
2. Helps Improve the Appearance of Deep Wrinkles
- A well-established ingredient in formulas targeting the appearance of deep wrinkles and expression lines.
- Often combined with other cosmetic peptides for a multi-angle anti-aging approach.
3. Supports Firmness, Elasticity & a Smooth Texture
- Designed to support a supple, resilient skin feel.
- Helps refine the look of the skin surface, supporting a smoother, more even appearance.
4. Supports Skin Comfort & a Calm-Looking Complexion
- Palmitoyl Tetrapeptide-7 is widely used in comfort-positioned concepts.
- Helps skin feel conditioned and cared for, including in formulas developed for sensitive skin.
5. Supports a Well-Conditioned, Youthful-Looking Appearance
- Helps maintain a healthy-looking, well-conditioned complexion.
- Designed for products targeting the visible signs of skin aging.
6. A Gentle, Retinol-Free Option in Anti-Aging Concepts
- A well-tolerated ingredient for daily-use formulas.
- A popular choice for consumers looking for a gentle, retinol-free anti-aging routine.
- Easy to incorporate across a wide range of textures, from serums to creams.
Applications
- Anti-Aging Serums & Ampoules – High-performance concentrates targeting fine lines, loss of firmness and dull skin.
- Eye Contour Creams & Serums – Gentle yet effective formulations for the delicate eye area (crow's feet, under-eye lines).
- Firming & Elasticity Formulations – Products designed to support a bouncy, resilient skin feel.
- Daily Moisturizers & Creams – Everyday anti-aging care for all skin types.
- Neck, Hand & Body Care – Multi-area anti-aging care.
- Anhydrous & Oil-Based Systems – The freeze-dried powder format supports balms, sticks and anhydrous serums.
- Multi-Peptide Anti-Aging Concepts – Blends with other cosmetic peptides for complete anti-aging routines.
OME service
Packaging & Shipping
Certification
Products Description
Q: What is Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7 Complex?
A: It is a two-peptide cosmetic active - a precise dual-peptide system, not a single ingredient. It contains two distinct peptides: Palmitoyl Tripeptide-1 (Pal-GHK) and Palmitoyl Tetrapeptide-7 (Pal-GQPR). On an INCI-compliant ingredient label, those two names are what you will see listed.
Q: How does the dual-peptide complex work?
A: Both peptides are matrikine-type signal peptides - short fragments derived from extracellular matrix proteins. They are widely used in anti-aging formulations and perform complementary roles: Palmitoyl Tripeptide-1 is used in firming and collagen-support positioning, while Palmitoyl Tetrapeptide-7 is used in skin-comfort positioning.
Q: How does this complex differ from single-peptide actives?
A: Single-peptide actives are built around one sequence. This complex combines two peptides in a 1:1 ratio, so formulators can address both firming and skin-comfort positioning in one ingredient.
Q: What is the solubility of the product?
A: The standard liquid grade is fully water-soluble. Freeze-dried powder is also available for anhydrous and oil-based formulations.
Q: What are the recommended usage levels?
A: Recommended usage varies by application:
- Standard 100 ppm solution: 3% – 8% in finished products
- General range: 0.01% – 0.5% active peptide
Please confirm the applicable usage limit for your target market before finalizing your formula.
Q: What is the optimal pH range for stability?
A: The complex is stable across pH 3.0 – 9.0, with optimal stability at pH 5.0 – 7.0.
Q: What ingredients work well with this complex?
A: It is commonly combined with:
- Hyaluronic acid – for hydration and a plump-looking finish
- Other cosmetic peptides – for multi-peptide anti-aging formulations
- Niacinamide (vitamin B3) – for radiance and evenness-positioned formulas
- Vitamin C derivatives – for antioxidant-positioned formulas
- Ceramides – for a comfortable skin feel
How To Contact Us?
For bulk inquiries, samples or custom specifications, please contact our sales team. We look forward to partnering with you for high-quality Palmitoyl Tripeptide-1 & Palmitoyl Tetrapeptide-7 Complex that meets your exact requirements.
If you need this product for your product lines, please contact us at ella.zhang@huilinbio-tech.com.
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