Xi'an Huilin Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of myristoyl hexapeptide-23 powder in China. With abundant experience, we are committed to providing high quality natural products with competitive price. Please feel free to wholesale bulk pure myristoyl hexapeptide-23 powder for sale here from our factory.
Product Description
Myristoyl Hexapeptide-23 (INCI: Myristoyl Hexapeptide-23) is a synthetic biomimetic lipopeptide with the amino acid sequence Myristoyl-Ala-Lys-Lys-Leu-Lys-Leu-NH₂ (Myr-AKKLKL). It consists of six amino acids (alanine, lysine and leucine) with a myristoyl fatty acid chain attached to the N-terminus.
The myristoyl modification significantly enhances lipophilicity, giving the peptide a strong affinity for lipid-rich systems and allowing it to be incorporated into both aqueous and emulsion-based formulas as well as oil-containing systems. This lipopeptide structure makes it a popular choice for blemish-prone skin care and anti-aging concepts, where a balanced, comfortable skin appearance is the goal.
Our Myristoyl Hexapeptide-23 Powder is manufactured through advanced Solid-Phase Peptide Synthesis (SPPS) followed by N-terminal myristoylation and rigorous HPLC purification. The result is a consistently pure (≥95%–98%), stable powder that meets the quality requirements of skincare brands worldwide.
Key Features & Advantages
- Lipopeptide Design – A myristoylated signal peptide that combines a lipid chain with a short bioactive sequence in a single molecule.
- Designed for Blemish-Prone Skin Care – Well suited to formulas positioned for oily, combination and blemish-prone skin types.
- Signal Peptide Activity – Belongs to the family of signal peptides widely used in skin care to support the look of firmer, smoother skin.
- Supports a Firm, Supple Skin Feel – A popular choice in anti-aging concepts targeting the appearance of fine lines and loss of firmness.
- Enhanced Lipophilicity – The myristoyl chain improves affinity with lipid-rich systems and the skin's lipid barrier, supporting even distribution in formulation.
- High Purity – Available in ≥95% and ≥98% purity (HPLC) with full analytical documentation.
- Formulation Versatility – White powder format; easy to incorporate into aqueous, emulsion and oil-containing systems.
- Synthetic & Animal-Free – 100% synthetic production via SPPS; vegan and cruelty-free.
- Regulatory Documentation – Listed in CosIng (EU); a complete technical file is available to support your compliance review. Intended for cosmetic use only.
Technical Specifications (Typical – ≥98% Grade)
| Parameter | Specification | Test Method |
|---|---|---|
| Product Name | Myristoyl Hexapeptide-23 | - |
| CAS Number | Not publicly assigned | - |
| INCI Name | Myristoyl Hexapeptide-23 | - |
| Synonyms | Myristoylated signal peptide | - |
| Amino Acid Sequence | Myristoyl-Ala-Lys-Lys-Leu-Lys-Leu-NH₂ (Myr-AKKLKL) | - |
| Molecular Formula | C₄₇H₉₂N₁₀O₇ | - |
| Molecular Weight | 909.3 g/mol | - |
| Appearance | White to off-white powder | Visual |
| Assay (Purity) | ≥98.0% (HPLC) | HPLC |
| Purity (≥95% grade) | ≥95.0% (HPLC) | HPLC |
| Solubility | Water-soluble | - |
| Loss on Drying | ≤5.0% | 105°C |
| Heavy Metals | No heavy metals | ICP-MS |
| Total Plate Count | ≤100 CFU/g | USP <61> |
| Yeast & Mold | ≤10 CFU/g | USP <2021> |
| E. coli | Negative | USP <2022> |
| Salmonella | Negative | USP <2022> |
Specifications are for reference. Please request the current COA for batch-specific data.
Key Skin Benefits
Myristoyl Hexapeptide-23 is a dual-positioning lipopeptide used in both blemish-prone skin care and anti-aging concepts. Key highlights:
1. Supports the Appearance of Clearer-Looking, More Balanced Skin
Designed for formulas positioned for oily and blemish-prone skin types, helping skin look clearer and more balanced over time.2. Helps Comfort the Look of Stressed, Reactive Skin
Supports a calm-looking complexion and a comfortable skin feel, making it suitable for formulas designed for reactive skin types.3. Supports a Firmer, More Supple Skin Appearance
Helps maintain the look of firmness and structural resilience, so skin appears smoother and better supported.
4. Supports Skin Firmness & Elasticity
Contributes to a skin feel that is firm and elastic, helping offset the appearance of sagging and loss of elasticity.
5. Supports a Smooth, Youthful-Looking Appearance
Widely used in anti-aging skin care to help reduce the visible appearance of fine lines and wrinkles.
6. Supports a Fresh, Non-Greasy Skin Feel
Helps skin look and feel less oily, making it particularly suitable for oily and combination skin types.
Applications
- Blemish-Prone Skin Serums & Gels – Targeted serums, gels and creams for oily and blemish-prone skin.
- Oil-Control Toners & Serums – Lightweight formulations for oily and combination skin types.
- Anti-Aging & Firming Creams – Products addressing both skin clarity and the appearance of aging.
- T-Zone & Pore-Refining Formulas – Products positioned for visible pores and uneven skin texture.
- Daily Moisturizers – Everyday care for blemish-prone and maturing skin.
- Body Care – Products for the chest and back area.
- Anhydrous & Emulsion Systems – Suitable for oil-containing and emulsion-based formats.
- Multi-Peptide Concepts – Combined with other cosmetic peptides in anti-aging and clarifying concepts.
Frequently Asked Questions (FAQ)
Q: What is the difference between Myristoyl Hexapeptide-23 and Hexapeptide-23?
A: Myristoyl Hexapeptide-23 is the myristoylated (lipidated) derivative of Hexapeptide-23. The myristoyl fatty acid chain significantly enhances lipophilicity, giving the peptide a stronger affinity for lipid-rich systems and the skin's lipid barrier. Hexapeptide-23 (the non-lipidated form) functions primarily as a skin conditioning agent, while the myristoylated derivative is designed for improved lipid affinity and distribution in formulation.
Q: What are the recommended usage levels?
A: Recommended usage varies by application: Leave-on facial serums and creams: 0.5% – 2%; General leave-on products: 0.1% – 0.5%; Oil-control toners: 0.1% – 0.3%; Concentrated active formulations: Up to 5%.
Q: What is the optimal pH range for stability?
A: Myristoyl Hexapeptide-23 is stable across a broad pH range of 4.0 – 7.5, making it compatible with most cosmetic formulations. Compatibility is typically assessed in the pH 5.0 – 7.0 range.
Q: At what stage should Myristoyl Hexapeptide-23 be added to formulations?
A: Add during the cooling phase (below 45°C) at the final stage of formulation to preserve peptide integrity.
Q: What ingredients work well with Myristoyl Hexapeptide-23?
A: Myristoyl Hexapeptide-23 is commonly combined with:
- Salicylic acid – Pore-refining and skin-clarifying concepts
- Niacinamide – Soothing and barrier-supporting benefits
- Hyaluronic acid – Hydration and a smoother skin feel
- Other cosmetic peptides – Multi-peptide clarifying and anti-aging concepts
- Retinol derivatives – Combined anti-aging positioning
Q: What should be avoided when formulating?
A: Avoid strongly acidic (pH < 3) or strongly alkaline (pH > 9) conditions, as this may affect peptide stability.
Q: Is Myristoyl Hexapeptide-23 approved for use in cosmetics globally?
A: EU: Listed in CosIng (COSING Ref No: 85277); used in formulations compliant with Regulation 1223/2009. Global: widely used in cosmetic formulations across major markets. For individual markets, we recommend confirming the current local inventory status before making any compliance claim.
Company Introduction
Xi'an Huilin Bio-tech Co., Ltd. is a leading provider of premium plant extracts for health applications. We supply herb extracts, standardized extracts, and fruit/vegetable powders. Dedicated to quality and innovation, we serve global customers in the supplements, food, and cosmetic industries, advancing human health. Click here to learn more.
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How To Contact Us?
For bulk inquiries, samples or custom specifications, please contact our sales team. We look forward to partnering with you for high-quality Myristoyl Hexapeptide-23 Powder that meets your exact requirements.
If you need this product for your product lines, please contact us at ella.zhang@huilinbio-tech.com.
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