Hydroxypinacolone Retinoate Powder

1, Introduction

Hydroxypinacolone Retinoate powder is a retinol derivative that can directly bind to cellular retinoic acid receptors (RARs). Reduce seborrhea, dilute epidermal pigment, prevent skin aging, treat acne, whiten and fade spots, etc. While ensuring the powerful effect of retinoic acid, it greatly reduces its irritation, mainly used for anti-aging, wrinkle removal and acne recurrence.

2,Chemical Properties

3,Key Benefits

✅ Clinically Proven Anti-Aging:

Stimulates collagen synthesis & reduces wrinkles without irritation (unlike retinol). Proven efficacy at 0.1–0.5% in 8-week human trials ^[1].

✅ Zero Sensitivity Risk:

Bypasses retinoic acid receptors – non-irritating for rosacea/eczema-prone skin ^[2].

✅ Photostability:

Resists UV degradation (t1/2 >24h vs. retinol's 30min) – ideal for daytime formulations.

✅ Bioavailability Boost:

Penetrates stratum corneum 5x faster than retinol ^[3].

✅ Antioxidant Synergy:

Enhances efficacy of vitamin C/niacinamide in combating oxidative stress.

4,Application Fields & Formulation Guidelines

5,Suggested Usage Protocol

Step-by-Step Integration:

Solubilization:

Dissolve HPR powder in ethanol/propanediol (1:2 ratio) at 40°C.

Emulsion Phase Addition:

Add to oil phase <60°C for anhydrous systems.

Add to water phase <45°C for serums (pH 5.0–6.5).

Preservation:

Use phenoxyethanol (1.0%) + ethylhexylglycerin (0.5%).

Stability Optimization:

Avoid strong oxidizers (e.g., benzoyl peroxide).

Use opaque/airless packaging to prevent photodegradation.

6,Precautions

It is added at low temperature during the formulation process, preferably below 40°C. The optimum pH range of the system is 5.0-6.3, and the finished product should be protected from direct sunlight (with opaque packaging). It is recommended to add UV absorbers to day care products.

7,Certification

8,Packaging

9,How to pay

10,Shipping

11,Contact Us

you can contact us an email: ella.zhang@huilinbio-tech.com, we are looking forward to cooperating with you!

References Embedded:

J. Cosmet. Dermatol. (2019): [10.1111/jocd.12822]

Dermatol. Ther. (2020): [10.1111/dth.13145]

Int. J. Pharm. (2021): [10.1016/j.ijpharm.2021.120123]

Why choose us?

• We work closely with our customers to understand their needs.
• Our efforts are reflected in any small activities that create value for customers, and the time and energy spent by each employee to improve their own abilities.
• We strive to ensure our customers always receive top-quality products and services.
• We adhere to the honest and pragmatic style, create value with products and services, and strive to be the leader of high-quality Hydroxypinacolone Retinoate Powder.
• We are a Chinese-based factory that caters to the needs of both suppliers and manufacturers.
• We continuously strengthen the project management ability and the improvement of all management levels.
• We use the latest technology to create the highest quality products.
• Our company is stepping into the tide of market economy development with professional dedication, exquisite products and attentive service. We sincerely invite people with lofty ideals to join and cooperate to create brilliant!
• Our commitment to quality is second to none.
• We strive to grasp the industry and industry development trend, assiduously improve our Hydroxypinacolone Retinoate Powder.

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