Product Description
Bremelanotide (PT-141) is a synthetic heptapeptide analog of α-melanocyte-stimulating hormone (α-MSH). As a selective melanocortin receptor agonist, this research compound represents a valuable tool for studying receptor signaling pathways. Our high-purity PT-141 peptide is manufactured under stringent quality control conditions, providing researchers with a reliable research chemical for investigating melanocortin system mechanisms. This pharmaceutical intermediate is ideal for advanced biochemical investigations and receptor binding studies in scientific research applications.
Physicochemical Properties
| Property | Specification |
|---|---|
| Product name | Bremelanotide (PT-141) |
| Product appearance | White to off-white lyophilized powder |
| Molecular formula | C50H68N14O10 |
| Molecular weight | 1025.2 g/mol |
| CAS NO | 189691-06-3 |
| Purity (HPLC) | >98% |
| Shelf life | 24 months |
| Solubility | Soluble in water, acetic acid solution; sparingly soluble in organic solvents |
| Storage | Store at -20°C in airtight container. Protect from light and moisture. |
Key Characteristics
This synthetic peptide provides researchers with several distinct technical advantages for specialized investigations:
- Targeted Receptor Engagement: Demonstrates selective affinity for melanocortin receptors MC1R and MC4R, serving as a precise pharmacological tool for studying receptor activation mechanisms and ligand-receptor interactions.
- Chromatographic Purity: Exceeding 98% purity by HPLC analysis guarantees minimal contaminant interference, ensuring dependable and consistent experimental data across research studies.
- Lyophilization Stability: The freeze-dried formulation preserves molecular integrity under recommended storage conditions, providing extended viability for long-term research programs without degradation concerns.
- Methodological Flexibility: Compatible with diverse research methodologies including in vitro binding assays, cellular response studies, and mechanistic pathway investigations in controlled laboratory settings.
- Manufacturing Reproducibility: Implemented quality assurance protocols maintain identical peptide characteristics across production batches, supporting reproducible scientific findings and experimental validation.
Research Applications
Bremelanotide (PT-141) facilitates advanced scientific exploration in multiple research domains:
1. Neuropharmacology Studies:
- Examination of melanocortin-mediated neural signaling pathways
- Investigation of blood-brain barrier penetration mechanisms
- Analysis of neuropeptide distribution and metabolism
2. Receptor Pharmacology:
- Quantitative binding affinity measurements at melanocortin receptor subtypes
- Structure-activity relationship modeling of peptide analogs
- Competitive binding and receptor activation profiling
3. Cellular Signaling Research:
- Second messenger system activation studies (cAMP, calcium flux)
- Intracellular signaling cascade analysis
- Receptor internalization and recycling mechanisms
4. Analytical Development:
- Mass spectrometry reference standard for peptide quantification
- Chromatographic method development and validation
- Quality control protocol establishment for peptide-based compounds
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Frequently Asked Questions (FAQ)
Q: What quality control measures are implemented for your Bremelanotide (PT-141)?
A: Each batch undergoes rigorous testing including HPLC-UV for purity verification (>98%), mass spectrometry for structural confirmation, and amino acid analysis for sequence validation. Full Certificate of Analysis is provided with every shipment.
Q: Can you supply Bremelanotide in bulk quantities for large-scale research programs?
A: Yes, we specialize in bulk manufacturing and can supply multi-kilogram quantities. Our production capacity supports large-scale research requirements with maintained quality and batch consistency.
Q: What is your typical lead time for bulk orders of GMP-grade Bremelanotide?
A: Standard lead time for GMP-grade bulk orders is 6-8 weeks after order confirmation. Accelerated production options are available for urgent research requirements.
Q: Can you provide stability data and recommended storage conditions for long-term storage?
A: Comprehensive stability data is available in our technical dossier. For long-term storage, we recommend -20°C in sealed containers with desiccant. Under these conditions, the product maintains stability for 24 months.
Q: What is your minimum order quantity for custom synthesized Bremelanotide analogs?
A: MOQ for custom analogs is typically 5 grams. However, this may vary based on sequence complexity and modification requirements. Please consult with our technical team for specific projects.
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How To Contact Us?
If you need this product for your research requirements, please get in touch with us at ella.zhang@huilinbio-tech.com to discuss sourcing Bremelanotide for research purposes.
Disclaimer
Bremelanotide peptide is intended for research purposes only. Not for diagnostic, therapeutic, or consumer applications. All research must comply with applicable regulations and institutional guidelines.
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