Description of pueraria lobata root extract
Puerarin Powder is herb extract. Pueraria root extract is Puerarialobata(Willd.)Ohwi or PuerariathomsoniiBenth, a leguminous plant. The dried root extract mainly contained flavonoids such as Diadzin, Diadzein, Puerarin, Xylopuerarin, 7-glucoside, puerarin - 7-xyloside, etc. Puerarin can dilate coronary Chemicalbook arteries and cerebral arteries, reduce blood pressure, slow heart rate, reduce myocardial oxygen consumption, relieve hypertension, dizziness, headache, neck stiffness and other symptoms in patients with coronary heart disease, and restore and enhance memory. It also has the effect of antithromboxin A2, increasing PGI2 and HDL, and thus can combat vasospasm, inhibit platelet aggregation and reduce blood viscosity. It is suitable for coronary heart disease and angina pectoris, can prevent myocardial infarction and cerebral thrombosis, and is effective for vertigo and sudden deafness, and can also be used for auxiliary treatment of hypertension and arrhythmia.
What is Pueraria lobata used for?
1. Dilating coronary vessels and improving myocardial ischemia and hypoxia can slow down the heart beat rate, enhance myocardial contractility and reduce aortic pressure (MAP). Reduce the resistance of the lateral rami coronary arteries. PGF12 can significantly relieve angina pectoris and improve ischemic electrocardiogram. The blood levels of 6-K-PGF12 and HDL(high density lipoprotein) were increased, and the coronary artery and peripheral vascular dilated. Pueraria flavonoids can significantly increase coronary blood flow, relax vascular smooth muscle and reduce peripheral resistance. Cardiac output did not change significantly, but left ventricular pulsation decreased slightly. Intravenous injection of pueraria flavone can increase the oxygen content in deficient blood pressure and decrease the lactic acid content, which has a good effect on improving the metabolism of normal and ischemic myocardium. Pueraria total flavonoids, daidzein and puerarin can all counteract myocardial ischemia caused by pituitrin and have obvious anti-hypoxia effect. Puerarin can reduce myocardial oxygen consumption and improve myocardial working efficiency. Meanwhile, it can dilate coronary vessels, increase coronary blood flow, reduce resistance and increase oxygen supply, so as to improve the balance of oxygen supply and demand.
2. Antihypertensive effect Puerarin and daidzein have obvious curative effect on hypertension caused by headache, dizziness, tinnitus and other symptoms. Intravenous injection of pueraria extract, total flavone and puerarin reduced the blood pressure of normally anesthetised dogs. Decoction and alcohol extract given to renal hypertensive dogs also have a certain antihypertensive effect. Intraperitoneal injection of puerarin can significantly reduce the blood pressure and slow the heart rate of awake spontaneously hypertensive rats (SHR). The serum renin activity (PRA) of SHR can be significantly decreased. Daidzein solid dispersion had relatively early and weak antihypertensive effect on anesthetized rabbits.
3. Inhibition of platelet aggregation in vitro Puerarin can inhibit ADP-induced platelet aggregation in rats, and also inhibit ADP and 5-HT induced platelet aggregation in rabbits, sheep and normal people. It also inhibited the release of 3H-5- HT in rat platelets.
4. Blocking effect of β-adrenergic receptor Pueraria extract has antagonistic effect of isoproterenol on various tissues with β-adrenergic receptor. Puerarin can significantly reduce the maximum binding capacity of β-receptor in rat myocardial membrane preparation. The activation of adenylate cyclase by epinephrine was completely inhibited. It shows that it has a wide range of β-receptor blocking effects.
5. Antiarrhythmic effects Pueraria flavonoids, daidzein and pueraria ethanol extract have obvious anti-arrhythmic effects on aconitine, barium chloride, calcium chloride, chloroform-epinephrine and acute myocardial ischemia.
6. Improving cerebral blood circulation effect Total flavonoids of Pueraria can increase cerebral blood flow, decrease cerebral vascular resistance, and significantly improve the microcirculation disturbance caused by local drops of norepinephrine. Intramuscular injection in hypertensive arteriosclerosis patients can reduce cerebrovascular resistance, shorten blood inflow time, and mildly improve cerebral blood circulation.
7. Puerarin Powder has Effects on smooth muscle A variety of isoflavones in Pueraria root may be antispasmodic components of diastolic smooth muscle, and contractile components may be choline-acetylcholine and Casein R, especially daidzein, which has antiacetylcholine effects.
8. Antioxidant effect The purified flavonoid PG1 isolated from pueraria root can significantly inhibit the hemolysis of red blood cells caused by oxidative damage, and inhibit the formation of lipid peroxide caused by the reactive oxygen species (-- OH, O2-) of microsomes.
9. Hypoglycemic effect mice were given puerarin intragastric administration, which had inhibitory effect on hyperglycemia induced by alloxacil. The hypoglycemic effect of puerarin and aspirin was observed only in adrenaline-induced hyperglycemia in mice. Pueraria decoction has a slight hypoglycemic effect on normal rabbits.
10. Improving learning and memory function of Pueraria alcohol extract and total flavonoids can counteract memory acquisition disorders induced by scopolamine and memory re-impairment induced by 40% ethanol in mice. Pueraria alcohol extract can also counteract the inhibition of scopolamine induced manipulative conditioning in rats.
11. Effect on Immune function Pueraria extract can enhance the function of macrophages to phagocytose carbon granules. The decoction can enhance the phagocytosis of Staphylococcus aureus in vitro. The hybrid and C3H pure line mouse lymphocytes cultured with pueraria solution and PHA or concanavalin A can promote the "eluvial transfer" effect.
Characteristics of puerarin powder
Natural source: Puerarin powder is a natural plant component extracted from Radix Puerariae, and does not contain any chemical additives or synthetic substances. Therefore, it is considered as a natural and safe nutritional supplement.
Nutrient-rich: Puerarin powder is rich in a variety of nutrients, including many different types of flavonoids, isoflavones, flavonoids and so on. These components have multiple health care functions such as antioxidation, anti-inflammation, regulating blood sugar and promoting cardiovascular health.
Easy absorption: The effective components in puerarin powder are easy to be absorbed and utilized by human body, which can quickly exert the health care effect.
Various applications: Puerarin powder can be used as a nutritional supplement or additive in various foods and health products. For example, it can be added to drinks, dairy products, cakes, health products and so on.
Health benefits of puerarin powder
Antioxidant effect: Puerarin powder is rich in antioxidants, such as flavonoids and isoflavones, which can help fight the damage of free radicals, reduce the oxidative stress of cells, and then slow down the aging process.
Regulating blood sugar: Some studies show that puerarin powder may have the potential to regulate blood sugar level. It can affect insulin secretion, promote the utilization of glucose and reduce the peak value of blood sugar, which is helpful to control blood sugar fluctuation.
Support cardiovascular health: the active ingredients in puerarin powder are considered to be beneficial to cardiovascular system. It can promote blood circulation, dilate blood vessels, lower blood pressure, reduce the risk of arteriosclerosis and protect the heart.
Anti-inflammatory effect: the ingredients in puerarin powder have anti-inflammatory effect, which can alleviate inflammatory reaction and discomfort caused by inflammation. This may be beneficial to relieve arthritis, asthma and other inflammation-related diseases.
Promoting the health of digestive system: Puerarin powder is considered to have a positive effect on digestive system. It may help to relieve stomach discomfort and promote intestinal health by increasing gastric juice secretion, improving intestinal peristalsis and protecting gastric mucosa.
What fields can puerarin powder be used in?
Food industry: Puerarin powder can be used as an additive to various foods, such as beverages, dairy products, cakes, snacks, etc., to increase its nutritional value and functionality.
Drug field: The active ingredients in puerarin powder are widely used in traditional Chinese medicine preparations to treat some diseases or as adjuvant therapy. Puerarin powder is considered to have the functions of anti-inflammation, anti-oxidation, regulating blood sugar and lowering blood pressure, and can be used for the treatment of cardiovascular diseases, diabetes, arthritis and other diseases.
Health care products market: Puerarin powder can be used as health care products to provide a variety of nutrients and functional components, such as antioxidants, blood sugar regulators, cardiovascular support agents and so on. It can be used to promote overall health, prevent diseases and maintain body functions.
Cosmetics and personal care products: the ingredients in puerarin powder have antioxidant and anti-inflammatory effects, and can be used in cosmetics and personal care products, such as facial skin care products, masks, shampoos, etc., to provide the effect of protecting skin and hair.
Identification of pueraria lobata root extract
Identify Kudzu Kudzu cut lengthwise square thick slices or small squares, 5 ~ 35cm in length, 0.5 ~ 1cm in thickness. Skin light brown, with long transverse holes and longitudinal wrinkles, rough. Section yellowish white or light brown, texture is not obvious. It is tough and fibrous. No breath, slightly sweet taste. Pink arrowroot is cylindrical, fusiform or semi-cylindrical, 12 ~ 15cm long, 4 ~ 8cm in diameter, some for the longitudinal or oblique cut thick slice, the size is different. Concentric rings formed by fibers can be seen on the transverse section, and several longitudinal lines formed by fibers can be seen on the longitudinal section. Weight, hard quality, rich powder. It is better to have large size, white color, solid quality, powder foot and little fiber. Microscopic identification powder light brown, yellowish white or light yellow.
① There are many starch granules, which are spherical, semicircular or polygonal, 3-37 μm in diameter, Chemicalbook umbilical point, crack or star. The complex granules consist of 2 ~ 10 granules.
② Fiber bundle, thick wall, surrounding cells mostly containing calcium oxalate square crystal, the formation of crystalline fiber.
③ Stone cells are rare and round or polygonal. Physicochemical identification 0.8g powder was taken, added with 10ml methanol, placed for 2h, filtered, the filtrate dried, added with 0.5ml methanol to dissolve, and used as the test solution. 1mg/ml methanol solution was prepared from puerarin reference. Absorb 10μl of each of the above solutions and point them on the same silica gel H thin plate with CMC-Na as adhesive. The solution is formed into strips. The solution is expanded with chloroform-methanol-water (7∶2.5∶0.25) and examined under ultraviolet lamp (365nm). The chromatogram of the test product showed fluorescent stripes of the same color at the corresponding position with that of the control product.
How to contact us?
Our company is a professional supplier of semi-finished raw materials, including plant extract, fruit and vegetable powder, cosmetics, tablet candy and other kinds of products; Our products are supplied directly from the manufacturer, so the price is very favorable, and the quality is guaranteed, so you can rest assured to buy. Currently, our company is selling Puerarin Powder of high quality, which is a high quality additive material for health care products, medicine, skin care and other products.
If you are interested in this product and want to know more about it, you can consult our account manager through the international website or email, our email address is ella.zhang@huilinbio-tech.com; Offline you can come to see the factory, our factory is located in Fengze Science Park B, 170 Yanta District West Street, Xi 'an, Shaanxi Province, Room 706.