What Is Imperatorin Powder?

Mar 14, 2024 Leave a message

Product introduction

 

Imperatorin Powder is extracted from Angelica. it belongs to plant umbelliferae angelica dahurica Angelicadahurica (he. ExHoffm.) Benth. EtHook. Angelica dahurica f or hangzhou Angelicadahurica (he) exHoffm)) BenChemicalbookth. EtHook. F. var.formosana(Boiss.)ShanetYuan dried root was extracted as raw material. It mainly contains coumarin and volatile oil components, and has anti-inflammatory, analgesic, inhibition of pathogenic microorganisms, liver protection and other pharmacological activities.

Dahurica dahurica mostly grows on river banks, streams, fields or mountain forest margins. Xing 'an Angelica, also known as horse celery, can also be seen on the coastal jungle conglomerate. Xingan Angelica Dahurica is distributed in Heilongjiang, Jilin, Liaoning and other places. Today it is cultivated in Sichuan, Henan, Hubei, Hunan, Anhui, Shanxi and so on. Sichuan Angelica Dahurica, also known as alien Angelica, is distributed in Heilongjiang, Jilin, Liaoning and Sichuan. Today, Sichuan, Shandong and other cultivation. Hangdahurica dahurica, also known as Zhejiang Dahurica, is distributed in Zhejiang, Taiwan and other places. Cultivated in Zhejiang and Jiangsu. Dahuricae dahuricae, also known as Yunnan cattle and windbreak, is distributed in Yunnan, Sichuan and other places. Yunnan has cultivation.

CAS

482-44-0

EINECS

207-581-1

Chemical formula

C16H14O4

Molecular weight

270.28

Density

1.1311 (rough estimate)

Melting point

98-100°C

Boiling point

333.4°C (rough estimate)

Flash point

224.9°C

Vapor pressure

3.13E-08mmHg at 25°C

Solubility DMSO

≥5mg/mL

Refractive index

1.4350 (estimate)

Storage condition

 -20°C

appearance

off-white to light brown

Maximum wavelength (λmax)

['301nm(MeOH)(lit.)']

 

Function

 

1. Antipyretic, analgesic and anti-inflammatory effects: Dahuricae dahuricae or Hangdahuricae Dahuricae decocting 15g (crude medicine) /kg by gavage has obvious antipyretic effect on rabbits with fever caused by subcutaneous injection of peptone on the back, and its effect is better than that of aspirin 0.1g/kg. The inhibition rates of acetic acid writhing reaction were 69.6%, 52.86% and 40.53%, respectively, of Dahuricae Dahuricae decoction, ether extract and water extract by intragastric administration of 8g /kg (crude drug). Moreover, the hot plate test in mice also results in an obvious increase of pain eliza - tion and gavage of decoction 4g (crude medicine) /kg of Angelica Dahurica, which also has an obvious inhibitory effect on ear inflammation of xylene induced mice. It was also reported that Angelica Dahurica had no inhibitory effect on the pain caused by tail-clamping and scalding.

2. Cardiovascular effects: The alcohol-extracted ether soluble components of Angelica Dahuricae and hangdahuricae Dahuricae have a significant dilatation effect on the removed ear vessels, while the water-soluble components of Angelica Dahuricae have a vasoconstriction effect. Angelicin, the coumadin component of Angelica Dahurica, has dilatation effect on coronary vessels. Isoprohumolactone can reduce the contractility of frog heart in vitro.

3. Imperatorin Powder have Effects on smooth muscle: the ether-soluble and water-soluble components of Angelica Dahurica or Hangzizhurica can inhibit the spontaneous movement of small intestine in vitro; Ether soluble components can also resist the tetanic contraction caused by lentil, methylnestine and barium chloride, and water soluble components can also resist the tetanic contraction caused by barium chloride. Isoimperatorin can relieve spasmolysis in rabbit ileum and enhance the contractility of rabbit uterus and muscle tension of earthworm.

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4. Influence on fat metabolism: xanthotoxin, impertinotoxin and hydrating and oxygenating impertinotoxin of dahuricu (Angeli-cadahuricavar.dahuricu) were co-incubated with rat adipocytes at the concentration of 5×10-4mol/L. Although it has no obvious effect on fat metabolism, it can enhance the lipolysis induced by epinephrine and ACTH, inhibit the insulin induced conversion from glucose to fat, and play an indirect role in promoting lipolysis and inhibiting fat synthesis.

5. Photosensitivity: The furan coumarin compounds contained in Angelica Dahurica have a photosensitive effect. When it enters the body, once it is exposed to sunlight or ultraviolet radiation, it can cause solar dermatitis on the skin of the exposed area, resulting in redness, swelling, increased pigment and epidermal thickening, etc., which can be used in photochemotherapy to treat psoriasis.

6. Anti-microbial action: Angelica Dahuricae has different degrees of inhibition on Escherichia coli, Soongshii and dysentery, Proteus, typhoid and paratyphoid, Pseudomonas aeruginosa, Vibrio cholerae, some gram-positive bacteria and Mycobacterium humanis in vitro. In the test tube, there were different degrees of inhibition on Tinea floccus epidermosum, tinea plasticum, tinea woolly, 1:3 water on tinea olduan, 1:10 decoction on trichophyton, trichophyton viola and tinea floccus epidermosum, etc.

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Characteristics of imperatorin powder

 

Natural plant extract: imperatorin powder is extracted from the plant of imperatorin (Osthenia) and belongs to natural plant components.
Anti-inflammatory effect: imperatorin powder is considered to have anti-inflammatory effect, which can help alleviate inflammatory reaction and relieve discomfort caused by related inflammation.
Antioxidant effect: imperatorin powder is rich in antioxidants, which can help remove free radicals and reduce the damage of oxidative stress to the body.
Liver protection: imperatorin powder is considered to have a protective effect on the liver, which can reduce liver damage and promote hepatocyte regeneration.
Anti-allergic effect: imperatorin powder is said to have certain anti-allergic effect, which can alleviate allergic reactions and related symptoms.


Application field of imperatorin powder

 

Liver protection: imperatorin powder is considered to help protect the liver, alleviate liver injury, promote hepatocyte regeneration, and may help improve liver function.
Anti-inflammatory and anti-oxidation: imperatorin powder is said to have a certain anti-inflammatory effect, which can reduce inflammatory reaction, and is rich in antioxidant substances, which helps to eliminate free radicals in the body and reduce oxidative damage.
Allergy regulation: Some studies show that imperatorin powder may have a certain regulatory effect on allergic reaction and can alleviate allergic symptoms.
Anti-tumor effect: Some preliminary studies show that imperatorin powder may have a certain inhibitory effect on some cancers, but more research is needed to confirm its role in tumor treatment.

 

How to contact us?

 

professional team

Our company is a professional supplier of semi-finished raw materials, including plant extract, fruit and vegetable powder, cosmetics, tablet candy and other kinds of products; Our products are supplied directly from the manufacturer, so the price is very favorable, and the quality is guaranteed, so you can rest assured to buy. At present, our company is selling Imperatorin Powder, which is a high-quality additive material for health care products, medicine, skin care and other products.

If you are interested in this product and want to know more about it, you can consult our account manager through the international website or email, our email address is ella.zhang@huilinbio-tech.com; Our factory is located in Room 706, Building B, Fengze Science Park, No.170 West Street, Yanta District, Xi 'an City, Shaanxi Province.

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