Potassium 4-Methoxysalicylate (INCI name: Potassium Methoxysalicylate) Its name is Potassium Methoxysalicylate, also known as 4-MSK. It is an effective medicinal product that everyone likes to use in cosmetics in recent years. Whitening ingredients, at present, the mainstream principle of most of the whitening ingredients on the market is: by inhibiting the activity of tyrosinase, thereby inhibiting the formation of melanin, to achieve the effect of skin whitening.
However, 4MSK has its own set of methods, the key is because it has a similar structure to salicylic acid, as shown below:
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(a) Potassium 4-methoxysalicylate (B) Salicylic acid
Salicylic acid is a simple phenolic compound, which is not only widely used in medicine and other fields, but also one of the commonly used functional ingredients in cosmetics. The mechanism of action of salicylic acid is to dissolve the structural formations between keratinocytes without affecting the active epidermal structure, so that the stratum corneum falls off and produces a desquamation effect, removes the accumulated thick stratum corneum, and promotes the metabolism of the skin stratum corneum.
Therefore, 4-MSK not only has the effect of inhibiting melanin production that other whitening ingredients have, but also has the effect of regulating the imbalance of keratinocyte proliferation and differentiation, thereby promoting the smooth release of excess melanin deposited in the skin and improving the condition of dark skin.
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Many experiments have proved that 4-MSK has a direct inhibitory effect on the production of melanin, and also has an effect on the proliferation and differentiation of keratinocytes. Both of these actions have a defensive effect on both the production and release of melanin, which leads to excess deposition of melanin in the skin.
The main features of Potassium 4-Methoxysalicylate (4MSK) are to whiten and balance skin tone, ease and reduce excessive pigmentation, correct epidermal dysplasia, improve keratinization process, promote melanin excretion, prevent freckles, pigmentation, and smooth skin . Makeup recommends that you use it within the prescribed range of use, so that it will not cause itching, erythema, no irritation, and no acne.