Product Introduction
Honokiol powder is tan to white fine powder of magnolia officinalis extract, Chinese medicine magnolia officinalis (MagnoliaofficinalisRehderetWilson) antibacterial action of active ingredients in skin. With special, lasting muscle relaxation and strong antibacterial effect, can inhibit platelet aggregation. Clinically, it is mainly used as antibacterial and antifungal drugs.
It is often mixed in the mountain foothills of 800 ~ 1700 meters above sea level and the mixed wood forest beside the roadside stream. It is a medium tree that likes light; Prefers cool and humid climate. It is suitable for a slightly acidic or neutral soil with deep fertile soil, loose soil, rich in humus and good drainage. Chemicalbook is mainly produced in Enshi, Jianshi, Badong, Yichang, Lichuan of Hubei Province, and Chengkou, Kaixian, Wuxi, Wushan, Shizhu, Wulong and Fengjie of Chongqing. In Chongqing, Yunyang, Wanzhou, Zhongxian, Fengdu, Fuling, Jiangjin, Qianjiang, Pengshui, Xiushan, Nanchuan and other places are also distributed.
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Properties |
White fine powder |
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English name |
Magnolol |
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alias |
5', 5-diallyl-2,2' -biphenyldichol |
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Chemical name |
6,6',7, 12-tetramethoxy-2,2'-dimethyl-1-beta-berbaman |
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Molecular formula |
C18H18O2 |
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molecular weight |
266.32 |
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CAS No. |
528-43-8 |
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Mp |
101~102 |
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UV |
λmax 293nm |
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Source |
Magnolia officinalis |
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Physical and chemical properties |
White to yellowish brown powder, easily soluble in benzene, ether, chloroform, ethanol, etc., but not soluble in water. Reaction with ferric chloride methanol solution, blue black, reaction with Millon reagent, brown precipitate, reaction with phloroglucinol hydrochloric acid solution, red precipitate. |
Benefits of honokiol
Treatment of ulcerative colitis and Crohn's disease: Magnolol can relieve the symptoms of these diseases, such as diarrhea, abdominal pain and bloody stool.
Anti-inflammatory effect: Magnolol has anti-inflammatory effect, which can relieve pain and inflammatory reaction.
Protect gastric mucosa: it can help protect gastric mucosa, reduce the damage of gastric acid to gastric wall, and help treat gastric ulcer.
Antibacterial effect: Magnolol has certain antibacterial effect, which can inhibit the growth of some bacteria and help to treat infectious gastrointestinal diseases.
Improve digestion: it helps to promote the secretion of digestive juice and improve digestive function, which is conducive to digesting food.
Regulating intestinal function: Magnolol can regulate intestinal peristalsis, slow down excessive intestinal activity, and help improve symptoms such as diarrhea.
Characteristics of honokiol
Therapeutic effect of digestive tract: Magnolol is mainly used to treat gastrointestinal diseases, especially ulcerative colitis and Crohn's disease. It can help relieve symptoms such as pain, diarrhea and bloody stool.
Anti-inflammatory and antibacterial effects: Magnolol has a certain anti-inflammatory effect, which can reduce the inflammatory reaction, and has a certain antibacterial effect, which can inhibit the growth of some bacteria.
Protect gastric mucosa: It can protect gastric mucosa, reduce the damage of gastric acid to gastric wall, and help to treat gastric ulcer.
Regulating intestinal function: Magnolol can regulate intestinal peristalsis, help to improve diarrhea and other symptoms, and help to regulate intestinal function.
Improve digestion ability: it can promote the secretion of digestive juice, improve digestive function and help digest food.
Less side effects: In general, magnolol has relatively few side effects, but it may still cause discomfort such as headache, nausea and vomiting.
Function of honokiol
(1) Antibacterial effect. The minimum inhibitory concentration (MIC) of magnolol was 25,-- 100pg/mLtl0 against Trichophyton trichophyton, Microspora plaster, Trichophyton floccus, Aspergillus Niger, Cryptococcus neoformans and Candida albicans. The minimum inhibitory concentration (MIC) for both Bacillus subtilis and Mycobacterium smegmatis was 51.tg/mlt¨. Honokiol is one of the main ingredients in mints and chewing gum because it kills bacteria in the mouth and eliminates bad breath.
(2) Honokiol Powder has Anti-inflammatory effect. Magnolol can inhibit lymphocyte germination, mouse ear swelling, reduce the permeability of capillary wall around the inflammation site, inhibit leukocyte migration and fibrous tissue proliferation in a dose-dependent manner. It can also change the pattern of cytokines in inflammatory diseases, reduce inflammatory factors and increase the production of anti-inflammatory factors. it found that tumor necrosis factor-A (TNF) in plasma and tissue during hemorrhagic shock. Only), and the anti-inflammatory proxy factor interleukin. 10(Ⅱ, lO) showed no change in organ tissue. The application of magnolol can reduce the concentration of the former and increase the content of the latter in the lung. The anti-inflammatory effect of magnolol may be related to inhibiting the metabolic pathway of AA and inhibiting the release of intracellular lysosomes. Researchers from Fujian Provincial Army Hospital of the Armed Police prepared rat neutrophil suspensions, and measured superoxide anion production and p by enzyme-labeling and fluorescence colorimetry, respectively. The release of glucosidase and the release of lysozyme. The results showed that magnolol could reduce the production of superoxide anion in neutrophils at 1 ~ 1009M/L, and significantly inhibit the activation of neutrophils at levels greater than 109M/L. Release of glucosidase and lysozyme . In addition, magnolol attenuates sepsis induced gastroenteritis.

(3) Muscle relaxation and anti-oxidation
Honokiol has significant, long-lasting muscle relaxation effects. Wang Jp[14] et al. took the mice with intra-abdominal injection of lipopolysaccharide-induced sepsis as experimental materials. Studies showed that magnolol could effectively promote intestinal transport and play a role in muscle relaxation. Compared with the mice without magnolysol-added, tumor necrosis factor (TNF). Only), chemotactic proteins. 1. mRNA synthase is also significantly reduced, and it also has antioxidant activity. Zhao Xiang B ["] et al. found that magnolol could inhibit muscle contraction caused by 40mM potassium chloride, 1 ttM carbylcholine and 109M hydroxytryptamine in a dose-dependent manner, and the application of more than 109M magnolol could prevent the influx and release of calcium ions.
(4) Effect on nervous system
Magnolol has obvious anti-anxiety effect. Magnolol can stimulate the opening of chloride ion channels and make the cell membrane in a state of hyperpolarization, which in turn reduces the excitability of neuron cells, thus achieving the effect of anti-anxiety. Magnolol can significantly inhibit morphine withdrawal, which is related to the inhibition of p in brain. Endorphins were involved and showed a dose-effect relationship citation.
(5) Other functions
Magnolol also has myocardial protective effect, inhibiting the occurrence of ventricular fibrillation and death, and inhibiting arrhythmia. Magnolol can inhibit the ligation of Shay's pylorus, gastric ulcer induced by water infiltration stress and duodenal spasm caused by histamine.
Honokiol can inhibit skin aging by inhibiting the nuclear transcription factor kB, and the addition of this pharmaceutical ingredient in sunscreen has achieved good market returns. Other studies have shown that magnolol can also be a candidate drug for the treatment of alcoholic fatty liver disease through antioxidant effects. Magnolol significantly inhibited the aggregation of platelet-rich plasma and ATP release induced by collagen and arachidonic acid in rabbits.
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Application of honokiol extract
Used for content determination/identification/pharmacological experiments, etc. Pharmacological effects: magnolol has obvious and lasting central muscle relaxation, central nervous system inhibition, anti-inflammatory, antibacterial, disease resistant progenitor, anti-ulcer, anti-oxidation, anti-tumor, inhibition of morphine withdrawal, inhibition of platelet aggregation and other pharmacological effects, magnolol is used for the treatment of acute enteritis. Bacterial or Amiba Chemicalbook dysentery. Chronic gastritis, etc. Among them, in terms of antibacterial activity, magnolol showed significant antibacterial activity against Gram-positive bacteria, acid-resistant bacteria, filamentous fungi, and more significant antibacterial action against Streptococcus mutans, with the strongest inhibitory effect on Staphylococcus. Clinically, it is mainly used to eliminate chest and abdominal congestion, calm central nervous system, athletes muscle relaxation, anti-fungal, anti-ulcer and other drugs.

How to contact us?
We are a company with many years of sales experience in the plant extract industry. After years of operation, we have a wide range of products, such as fruit and vegetable powder, cosmetics, tablet candy and other products. We are a professional raw material supplier. At present, our company is selling cheap bulk Honokiol Powder, which is widely used in health care products, medicine, cosmetics and other fields. Those who need to make health care products can buy this raw material. Meanwhile, as our products are sold directly from the manufacturer, the quality of our products is guaranteed.

If you need to buy or are interested in it, you can send an email to our work email address ella.zhang@huilinbio-tech.com through the international website. We will reply you as soon as you see the message. In addition, you can also visit the offline field. Our company is located in Room 706, Building B, Fengze Science Park, No. 170, West Street, Yanta District, Xi 'an City, Shaanxi Province. Welcome to your visit.






