Introduction
Turkesterone Powder is a premium botanical extract derived from Ajuga turkestanica, a plant native to Central Asia and traditionally used in folk medicine for its restorative and adaptogenic properties. Turkesterone, the primary bioactive phytoecdysteroid in this extract, is structurally similar to testosterone but does not bind to androgen receptors, meaning it may support anabolic activity without the androgenic side effects associated with synthetic anabolic steroids. Our extract is produced through advanced extraction and purification processes and standardized to consistent Turkesterone content for reliable batch-to-batch performance. It is widely used in sports nutrition and muscle-building supplement formulations.
Key Features & Advantages
- Standardized Turkesterone Content – Available in multiple potency grades (2%–95%) with consistent batch-to-batch performance verified by HPLC
- Non-Androgenic Mechanism – Turkesterone does not bind to androgen receptors, offering a natural alternative for muscle support without typical steroidal side effects
- Multiple Extraction Ratios Available – 10:1 and 20:1 ratio extracts available for formulators requiring lower-concentration botanical extracts
- Water-Soluble Formulation – Easily dispersible in aqueous systems, suitable for capsules, tablets, powders, and functional beverages
Technical Specifications (Typical – 10% Turkesterone Grade)
| Parameter | Specification | Test Method |
|---|---|---|
| Product Name | Ajuga Turkestanica Extract Turkesterone Powder | - |
| Botanical Source | Ajuga turkestanica (aerial parts) | - |
| CAS Number | 41451-87-0 (Turkesterone) | - |
| Active Ingredient | Turkesterone (phytoecdysteroid) | - |
| Molecular Formula | C₂₇H₄₄O₈ | - |
| Molecular Weight | 496.64 g/mol | - |
| Appearance | Brownish-yellow to light brown fine powder | Visual |
| Odor | Characteristic | Organoleptic |
| Assay (Turkesterone) | ≥10.0% (HPLC) | HPLC |
| Ecdysterone Content | Naturally present | HPLC |
| Particle Size | 95% pass 80 mesh | USP <786> |
| Solubility | Water-dispersible | - |
| Loss on Drying | ≤5.0% | USP <731> |
| Ash Content | ≤5.0% | USP <281> |
| Heavy Metals (Total) | ≤10 ppm | ICP-MS |
| Lead (Pb) | ≤2.0 ppm | ICP-MS |
| Arsenic (As) | ≤2.0 ppm | ICP-MS |
| Cadmium (Cd) | ≤1.0 ppm | ICP-MS |
| Total Plate Count | ≤1,000 CFU/g | AOAC |
| Yeast & Mold | ≤100 CFU/g | AOAC |
| E. coli | Negative | AOAC |
| Salmonella | Negative | AOAC |
Specifications are for reference. Please request the current COA for batch-specific data.
Health Benefits
Ajuga Turkestanica Extract Turkesterone is a scientifically studied botanical ingredient with benefits supported by animal research and preliminary human data. Here are the key highlights in simple terms:
1. May Support Muscle Protein Synthesis
Turkesterone is believed to work through the PI3K/Akt/mTOR signaling pathway, a cellular pathway involved in muscle protein synthesis. Animal studies suggest it may possess anabolic properties, and some research indicates it could be more potent than other phytoecdysteroids in this regard.
2. Non-Hormonal Anabolic Support
Unlike synthetic anabolic steroids, Turkesterone does not bind to androgen receptors. In vitro research indicates it may support muscle mass without the typical androgenic side effects of synthetic anabolic drugs.
3. Supports Physical Performance
Phytoecdysteroids, including Turkesterone, are investigated for their potential to enhance athletic performance and support muscle recovery in sports nutrition applications.
4. Supports Overall Wellness
Ajuga turkestanica preparations are traditionally used as anti-aging cosmeceuticals and for medicinal purposes, with research indicating potential benefits for general health and cardiovascular support.
5. Rich in Bioactive Compounds
The extract naturally contains multiple bioactive constituents, including ecdysterone (20-hydroxyecdysone), ajugachin B, and 8-O-acetylharpagide, which may work synergistically.
6. Note on Human Evidence
The current body of human clinical evidence on Turkesterone's anabolic effects is limited. A four-week study found no significant effects on body composition, handgrip strength, mood, or sleep quality. Suppliers should position this ingredient as a botanical extract with traditional and preliminary research support, not as a proven anabolic agent.
Applications
| Application Category | Specific Uses |
|---|---|
| Sports Nutrition Supplements | Capsules, tablets, and powders for muscle support and performance formulas; typical dose 500 mg daily |
| Pre-Workout & Recovery Blends | Combined with other performance ingredients for comprehensive sports nutrition products |
| Testosterone Support Formulas | Positioned as a natural, non-androgenic alternative in male vitality products |
| Functional Foods & Beverages | Fortified drinks and functional foods targeting active individuals |
| Cosmeceutical Applications | Anti-aging skincare formulations (traditional use of A. turkestanica preparations) |
| Research & Development | Raw material for phytoecdysteroid research and product development |
Recommended Usage Levels
| Application | Recommended Dosage |
|---|---|
| Sports Nutrition Capsules / Tablets | 500 mg per day (as used in clinical investigation) |
| Pre-Workout Blends | 250–500 mg per serving |
| Functional Beverages | 100–300 mg per serving |
| Functional Foods | 0.1%–2.0% of formulation |
We recommend conducting stability and efficacy testing for your specific formulation. Please note that doses above those investigated in clinical studies (500 mg/day) may carry unknown safety risks.
Frequently Asked Questions (FAQ)
Q: Is Turkesterone a steroid?
A: Turkesterone belongs to the ecdysteroid family, which are steroid hormones found in plants and insects. However, it is not an anabolic-androgenic steroid (AAS). Ecdysteroids should not be confused with controlled substances like synthetic anabolic steroids, which are illegal to possess without a prescription in many jurisdictions.
Q: Is Turkesterone a natural or synthetic ingredient?
A: Turkesterone is naturally occurring and is extracted from the Ajuga turkestanica plant. It is also found in other plant sources, including Cyanotis vaga and Rhaponticum carthamoides, as well as in foods such as spinach, asparagus, and quinoa.
Q: What is the recommended dosage?
A: The only published human clinical study on Turkesterone used 500 mg per day for four weeks. Doses above this level have not been systematically investigated, and a case report of liver injury involved approximately 160 mg per day – far exceeding studied doses. We recommend staying within clinically investigated ranges.
Q: Is Turkesterone safe?
A: Data on Turkesterone safety in humans is limited. Reported side effects are generally mild and gastrointestinal in nature, such as nausea and upset stomach, particularly when taken without food. A 2025 case report described drug-induced liver injury with autoimmune features in a patient taking approximately 160 mg of Turkesterone daily. The World Anti-Doping Agency (WADA) has placed ecdysterone on its Monitoring Program since 2020, though Turkesterone and its plant sources are not currently prohibited.
Q: Does Turkesterone actually work for muscle growth?
A: Animal and in vitro studies have shown potential anabolic effects, and some research suggests Turkesterone may be more potent than other phytoecdysteroids. However, the single published human clinical study found no significant impact on muscle mass or body composition after four weeks of supplementation. More large-scale, high-quality human studies are needed to substantiate the claimed benefits.
Q: What is the difference between Turkesterone and Ecdysterone?
A: Both are phytoecdysteroids. Ecdysterone (20-hydroxyecdysone) is the most abundant ecdysteroid in Ajuga turkestanica, while Turkesterone is a minor constituent that some animal studies suggest may possess greater anabolic potency. Our extract is standardized to Turkesterone content, with ecdysterone naturally present as a co-occurring compound.
Q: What ingredients work well with Turkesterone?
A: Turkesterone works synergistically with:
- Ecdysterone – Complementary phytoecdysteroid for enhanced anabolic support
- Creatine monohydrate – Performance and strength support
- Beta-alanine – Endurance and muscle buffering
- L-carnitine – Fat metabolism and energy support
- Ashwagandha – Adaptogenic and recovery support
For inquiries, quotations, or sample requests, please contact: sales@huilinbio-tech.com
References
- Mamadalieva NZ, et al. Comparative metabolic profiling and quantitative analysis of metabolites in different tissues of Ajuga turkestanica by ESI-UHPLC-QqTOF-MS and NMR. Scientific Reports. 2024;14:28179. doi:10.1038/s41598-024-71546-5.
- Zubeldia JM, Hernandez-Santana A, Jimenez-Del-Rio M, et al. In Vitro Characterization of the Efficacy and Safety Profile of a Proprietary Ajuga Turkestanica Extract. Chinese Medicine. 2012;3:215-222.
- Crisanti A, Silver T, Jiannine L, Antonio J. The effects of an ecdysteroid supplement on indices of physical and mental performance. Journal of the International Society of Sports Nutrition. 2025;22:2550140. doi:10.1080/15502783.2025.2550140.
- Operational Supplementation for Military Personnel (OPSS). Ecdysterone and Turkesterone Dietary Supplements. 2026.
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