Xi'an Huilin Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of polygonum cuspidatum extract powder in China. With abundant experience, we are committed to providing high quality natural products with competitive price. Please feel free to wholesale bulk pure polygonum cuspidatum extract powder for sale here from our factory.
Product Introduction
Polygonum Cuspidatum Extract Powder, commonly known as Japanese Knotweed Extract, is a highly valued botanical ingredient, renowned as one of the most concentrated natural sources of resveratrol. This powerful stilbenoid polyphenol has captured significant scientific and commercial interest for its wide-ranging bioactive properties. Our extract is meticulously produced from premium-quality roots, offering manufacturers a versatile and potent raw material to formulate advanced products targeting anti-aging, antioxidant defense, cardiovascular support, and metabolic health across the nutraceutical, cosmetic, and functional food industries.
Physical & Chemical Properties
| Parameter | Specification / Description |
|---|---|
| Product Name | Polygonum Cuspidatum (Japanese Knotweed) Root Extract Powder |
| Latin Name | Polygonum cuspidatum Sieb. et Zucc. |
| Part Used | Dried Root & Rhizome |
| Extraction Method | Water and/or Ethanol extraction, concentration, and spray drying. |
| Active Marker(s) | Resveratrol (Trans- form), Total Polyphenols |
| Available Specifications | Extract Ratios: 10:1, 30:1, 50:1. Standardized: Resveratrol 20%, 50%, 98% (HPLC). |
| Appearance | Fine, free-flowing, brown to brown-yellow powder. |
| Particle Size | 95% through 80 mesh |
| Loss on Drying | ≤ 5.0% |
| Heavy Metals | ≤ 10 ppm (Pb, As, Cd, Hg) |
| Residual Solvents | Meets ICH guidelines for ethanol, methanol, etc. |
| Microbiological | Total Plate Count ≤ 1000 CFU/g; Yeast & Mold ≤ 100 CFU/g. |
| Solubility | Highly soluble in water and various cosmetic/ food-grade solvents. |
Mechanism of Action: The Multifaceted Power of Resveratrol
The core benefits of Polygonum Cuspidatum extract are largely driven by resveratrol, which exerts its effects through several sophisticated molecular pathways, akin to a master cellular regulator:
Sirtuin Activation (SIRT1) & Caloric Restriction Mimetic: Resveratrol is a well-known activator of SIRT1, a key NAD+-dependent deacetylase enzyme. Activation of SIRT1 promotes cellular repair, enhances mitochondrial function, and supports genomic stability, mimicking the beneficial effects of caloric restriction-a proven strategy for promoting longevity and metabolic health in various models.
AMPK Activation & Metabolic Regulation: Similar to gypenosides, resveratrol potently activates AMP-activated protein kinase (AMPK). This "cellular energy sensor" increases glucose uptake, promotes fatty acid oxidation, and inhibits cholesterol synthesis, thereby supporting metabolic balance and insulin sensitivity.
Potent Antioxidant & Anti-inflammatory Agent:
- Antioxidant: Directly scavenges free radicals (ROS) and upregulates the body's endogenous antioxidant defense systems via the Nrf2 pathway.
- Anti-inflammatory: Inhibits key pro-inflammatory mediators and signaling pathways, such as NF-κB and COX-2, reducing the production of cytokines and prostaglandins that drive chronic inflammation.
Skin Health & Photo-protection: In cosmetics, resveratrol protects skin cells from UV-induced oxidative damage, inhibits collagen-degrading enzymes (MMPs), and may help mitigate hyperpigmentation by modulating melanogenesis. Its skin benefits include promoting a more youthful, even-toned complexion.
Key Benefits & Supported Health Areas
Scientific research supports the application of standardized Polygonum Cuspidatum Extract in the following areas:
- Anti-aging & Longevity Support: As a SIRT1 activator, it supports cellular health and resilience, contributing to healthy aging processes at the cellular level.
- Cardiovascular & Vascular Health: Promotes endothelial function (via increased nitric oxide), supports healthy lipid metabolism, and provides antioxidant protection for blood vessels.
- Metabolic Health & Blood Sugar Balance: Through AMPK activation, it aids in maintaining healthy glucose metabolism and insulin sensitivity.
- Neuroprotection & Cognitive Health: Its antioxidant and anti-inflammatory actions, along with potential to modulate brain-derived neurotrophic factor (BDNF), support neuronal health and cognitive function.
- Skin Vitality & Anti-aging (Cosmetic): Offers exceptional skin benefits by reducing visible signs of aging (fine lines, wrinkles), protecting against environmental stressors, brightening skin tone, and soothing irritation.
- Joint & Musculoskeletal Comfort: Its anti-inflammatory properties may help support joint health and comfort.
Primary Application Fields
1. Dietary Supplements & Nutraceuticals:
- Anti-aging/Longevity Formulas: Capsules and tablets targeting cellular health.
- Cardiovascular & Metabolic Support: Blends for heart health and blood sugar management.
- General Antioxidant & Inflammation Support: Broad-spectrum wellness supplements.
2. Cosmetics & Skincare:
- Anti-aging Serums & Creams: High-performance products for wrinkle reduction and firmness.
- Brightening & Evening Treatments: To improve skin tone and reduce hyperpigmentation.
- Protective Day Creams & Sun Care: To defend against UV and pollution-induced damage.
3. Functional Foods & Beverages:
- Enhanced Health Drinks & Shots: Fortified with resveratrol for antioxidant benefits.
- Specialty Health Foods: Incorporated into functional snacks or bars.
Frequently Asked Questions (FAQ)
Q: What is Polygonum Cuspidatum extract, and why is it a preferred source of resveratrol?
A: Polygonum Cuspidatum (Japanese Knotweed) root is one of the richest and most sustainable natural sources of resveratrol, containing significantly higher concentrations than grapes or berries. Our extract concentrates this compound, providing a reliable, potent, and cost-effective raw material compared to synthetic resveratrol or lower-yield botanical sources.
Q: Are there any safety concerns or contraindications?
A: Resveratrol is generally considered safe at recommended dosages. However, due to its biological activity, pregnant and breastfeeding women should avoid use. It may interact with blood-thinning medications (e.g., warfarin) and certain drugs metabolized by cytochrome P450 enzymes (e.g., some statins, calcium channel blockers). Consultation with a healthcare professional is advised for individuals with underlying conditions or on medication.
Q: How does this extract differ from pure, synthetic resveratrol powder?
A: While pure synthetic resveratrol offers a single compound, our Polygonum Cuspidatum Extract provides a "phytocomplex." It contains resveratrol alongside other native co-occurring compounds like polydatin (a resveratrol glucoside) and emodin. This natural matrix may support the absorption, stability, or synergistic activity of resveratrol, an advantage valued in holistic formulation approaches.
Product Classification
We have two production bases in Xi'an. From raw material procurement to production and processing, we operate in strict accordance with regulations. The production workshop adheres to aseptic and dust-proof treatment, and regularly organizes employee training to improve the overall quality of employees. A number of production lines have been established, and the products produced include plant extracts, Chinese herbal extract oils, plant essential oils, cosmetic raw materials, scientific research customized products, etc.
Product Packaging
Packaged in aluminum foil bags , cartons or special sealed cardboard drums .
Shipping Method
The transportation adopts a combination of international express, sea, air and other methods, which is economical, convenient and fast.
Payment Method
Payment methods are: Paypal/MoneyGram/Wu/banktransfer, etc.
Company Introduction
The company is located in a high-tech industrial park, has two production lines, and has established cooperative raw material bases in Gansu, Sichuan and other places. There are advanced testing instruments to monitor the quality in an all-round way to ensure that the products produced meet the relevant industry regulations.
Contacted Us
You can contact our customers through the international website or send us the products you need by email, Email: ella.zhang@huilinbio-tech.com. Looking forward to your cooperation!
Why choose us?
- We are a Chinese-based factory that caters to the needs of both suppliers and manufacturers.
- In the course of development in the new century, our company will continue to follow the principle of good faith and provide customers with efficient, safe and first-class Polygonum Cuspidatum Extract Powder and perfect services to enhance corporate image and competitiveness.
- Our prices may be competitive but our quality is always superior.
- The after-sales service department thinks about what customers think, is anxious about what customers are anxious, and solves problems for customers in the first time, so that customers can use our products at ease and comfort.
- We work tirelessly to ensure our customers always receive the best products and services.
- Because we are rapidly developing period, the company needs an excellent talent team, where you can fully play your intelligence.
- Our experienced professionals work tirelessly to ensure quality and efficiency.
- The company warmly welcomes people from all walks of life at home and abroad to come and guide, plan for the future and create brilliance together.
- We understand the importance of listening to our customers' needs.
- We work tirelessly to build the status of the industry, and believe that the company will lead the new generation of industry trends with our unique style.
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