Xi'an Huilin Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of hesperidin methyl chalcone powder in China. With abundant experience, we are committed to providing high quality natural products with competitive price. Please feel free to wholesale bulk pure hesperidin methyl chalcone powder for sale here from our factory.
What This Grade Is
Hesperidin methyl chalcone powder (CAS 24292-52-2) is not extracted from a plant. It is made by methylating hesperidin, the flavanone glycoside recovered from citrus peel, and the methylation converts the flavanone into a chalcone with better water solubility than its parent.
That origin explains the two things a buyer needs to know before writing it into a formula.
First, it is a mixture, not a single substance. Methylation does not stop at one product; the commercial material contains several methylated hesperidin chalcones, and C29H36O15 / 624.59 describes the principal component rather than the whole. A specification that quotes a formula without saying so is describing a molecule that does not exist on its own in the drum.
Second, the material is not interchangeable with hesperidin. Different molecule, different solubility, different assay basis. A formula written for hesperidin does not absorb this at the same percentage, and a specification written for hesperidin does not describe this.
Release Data
| Item | Specification | Method |
| Assay, as hesperidin methyl chalcone | ≥ 98.0 % | HPLC, main-peak area normalisation |
| Appearance | Yellow to orange-yellow powder | Visual |
| Identification | Retention time and UV spectrum concordant with reference | HPLC |
| Composition | Methylated hesperidin chalcone mixture; distribution reported per batch | HPLC profile |
| Solubility | Freely soluble in water, methanol and ethanol | Supplier characterisation |
| Loss on drying | Reported per batch | Gravimetric, 105 °C |
| Heavy metals, as Pb | Reported per batch | ICP-MS |
| Total plate count and moulds and yeasts | Reported per batch | Plate count |
| Conclusion | Conforms to the agreed specification when tested by the stated methods | / |
Every batch certificate carries the chromatogram, not only the number. On a mixture, the number without the profile tells a formulator very little.
Why the Assay Depends on the Peak
"98 %" on this product is a statement about a chromatogram, and chromatograms can be integrated differently.
Hesperidin methyl chalcone has no single reference peak that everyone agrees on. Commercial material is analysed by HPLC precisely because the composition needs resolving, and the literature carries dedicated methods for it. That means two suppliers can both report 98 % and be describing different sums of peaks.
Three questions settle it, and they belong in your incoming specification rather than in a conversation after the first shipment:
• Which peak the 98 % is measured against - the largest single peak, or the sum of the methylated chalcone group
• Which wavelength the detector runs at, and which reference standard the response factor comes from
• Whether the chromatogram is attached to the certificate
We report against a named reference standard with the chromatogram attached. If your specification says "≥ 98 % by HPLC" and stops there, that is the line we will ask you to make more precise.
INCI Identity and Where It Fits
For a cosmetic file, the entry that matters is not the CAS number but the INCI name:
| Field | Value |
| INCI name | Hesperidin Methyl Chalcone |
| EINECS | 246-128-2 |
| CosIng function | Antioxidant |
The function assigned in the EU inventory is antioxidant - the ingredient's role in the formulation, retarding oxidation and the rancidity that follows it. That is a technical function, and it is the one this page states.
Market use concentrates in leave-on products: aqueous serums and gels, emulsion systems, and formulations applied to a defined area rather than the whole face. The material's water solubility is the reason it appears in aqueous systems at all, where the parent hesperidin would not dissolve usefully.
Solubility and Handling
The material is freely soluble in water, methanol and ethanol, and aqueous solutions stay clear at working concentrations. It is normally pre-dissolved before addition rather than dusted into a batch, which also keeps the operator away from airborne powder.
Two handling points follow from the chemistry. The powder is light-sensitive in the same way most chalcones are, so drums are supplied light-protected and should stay that way. And because the assay is a chromatographic sum, moisture pickup during storage changes the number on the next certificate more than it changes the appearance of the powder - reseal after opening.
Questions Buyers Ask
Q: Is this the same material as hesperidin?
A: No. Hesperidin is the flavanone glycoside extracted from citrus peel; this is its methylated chalcone derivative, with different solubility and a different assay basis. The two are not interchangeable at the same percentage in a formula.
Q: Why does the certificate say 98 % when the material is a mixture?
A: Because 98 % is the summed methylated chalcone content measured against a named reference standard, not the purity of a single molecule. The chromatogram on the certificate shows how that sum was arrived at.
Q: Can you supply the chromatogram with the batch?
A: Yes. The profile is released with the certificate, because on a mixture the profile carries the information the number alone cannot.
Q: Is it water soluble?
A: Yes, freely soluble in water as well as in methanol and ethanol, and clear at working concentrations in water. This is the practical difference from hesperidin.
Q: What INCI name should I declare?
A: Hesperidin Methyl Chalcone, EINECS 246-128-2. The CosIng function is antioxidant.
Q: Which documents arrive with a batch?
A: Certificate of analysis with the chromatogram, assay, moisture, heavy metals and microbiological results; the specification sheet; and the safety data sheet.
Supplier
Hesperidin methyl chalcone powder is supplied by Xi'an Huilin Bio-Tech Co., Ltd. in cosmetic grade, with the chromatogram released alongside the assay figure on every batch.
Lead time and freight terms are quoted with the order; FOB, CIF and DDP are workable by destination.
This page describes a raw material for manufacturing use. It is not a finished consumer product, and nothing here is a statement about the effect of any product on any person. Regulatory status differs by market and is the buyer's determination; we supply the documentation a filing requires.
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