PQQ Powder

PQQ Powder

Chemical Name: Pyrroloquinoline Quinone Disodium Salt
CAS Number: 122628-50-6
Purity: ≥ 99% (by HPLC)
Appearance: Reddish-brown to red fine powder
Molecular Formula: C14H4N2Na2O8
Molecular Weight: 374.17 g/mol
Grade: Food Grade / Pharmaceutical Grade
Minimum Order Quantity (MOQ): 1 KG
Key Applications: Dietary supplements (e.g., PQQ supplement, PQQ and CoQ10 blends), nutraceuticals, functional foods & beverages, skincare & cosmetic formulations, sports nutrition products.
Certification & Documentation: COA (Certificate of Analysis) available. Sample available upon request.
Shelf Life: 24 months in original, unopened packaging.
Storage: Store in a cool, dry place
Supplier: Xi'an Huilin Biotechnology Co., Ltd.

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Product Introduction

Introduction

 

Pyrroloquinoline Quinone Disodium Salt, universally abbreviated as PQQ, is recognized as a potent redox cofactor and a novel bioactive compound with vitamin-like properties. While trace amounts are synthesized endogenously and obtained through a diet rich in fermented foods, fruits, and vegetables, the levels are often insufficient for optimal bioactive benefits. This has led to the development of high-purity PQQ powder as a key ingredient in advanced dietary supplements and health products.

 

Classified as a water-soluble quinone, PQQ plays a crucial role in cellular function, particularly in mitochondrial health and antioxidant defense. Its exceptional stability and bioavailability in its disodium salt form make it ideal for various nutraceutical and cosmetic applications. This product is manufactured under strict quality control standards, ensuring purity, safety, and efficacy for global markets in compliance with relevant food and pharmaceutical regulations.

 

PQQ bag real shot map

PQQ barreled real shot map

 

Biophysical & Chemical Parameters Table

 

Parameter Specification / Value
CAS No. 122628-50-6
Assay (HPLC) ≥ 99.0%
Appearance Reddish-brown to red homogeneous powder
Odor & Taste Characteristic, slight salty taste
Solubility Freely soluble in water
Molecular Formula C14H4N2Na2O8
Molecular Weight 374.17
Melting Point >300°C (decomposes)
Loss on Drying ≤ 5.0%
Residue on Ignition 22.0% - 26.0%
Heavy Metals (as Pb) ≤ 10 ppm
Arsenic (As) ≤ 2 ppm
Total Plate Count < 1000 CFU/g
Yeast & Mold < 100 CFU/g
E. Coli / Salmonella Negative

 

Mechanism of Action

 

The remarkable benefits of PQQ stem from its unique and multifaceted mechanism of action at the cellular level:

  1. Potent Mitochondrial Biogenesis: This is a key action of PQQ. It directly activates key signaling pathways (e.g., PGC-1α) that stimulate the creation of new mitochondria within cells, a process called mitochondrial biogenesis. More mitochondria enhance cellular energy (ATP) production, which is fundamental for the function of high-energy organs like the brain, heart, and muscles.
  2. Master Antioxidant & Redox Cycling: PQQ functions as a superior antioxidant, not merely by scavenging free radicals like Reactive Oxygen Species (ROS), but through a unique catalytic redox cycling capability. A single PQQ molecule can undergo thousands of redox cycles, neutralizing a vast number of free radicals, far exceeding the capacity of common antioxidants like vitamin C. It also helps regenerate other critical antioxidants like glutathione.
  3. Enzyme Cofactor Activity: PQQ serves as an essential redox cofactor for several bacterial dehydrogenases, influencing gut microbiota and overall metabolic health.
  4. Cell Signaling & Gene Modulation: It influences pathways related to cell growth, development, and protection. Notably, PQQ has been shown to promote the production of Nerve Growth Factor (NGF), supporting neuron health and function.
  5. Neuroprotective Effects: By supporting mitochondrial function, reducing oxidative stress in neural tissues, and promoting NGF, PQQ provides a comprehensive approach to supporting cognitive health and neuronal resilience.

 

Benefits of PQQ Powder

 

The mechanisms above translate into a wide range of evidence-supported benefits:

  • Cognitive & Neurological Support: Enhances memory, attention, and cognitive function. Its neuroprotective properties make it a subject of interest for long-term brain health. Often combined with CoQ10 for synergistic support of brain energy metabolism.
  • Enhanced Cellular Energy & Reduction of Fatigue: By promoting mitochondrial biogenesis, PQQ helps combat cellular-level fatigue, improving overall vitality and endurance, which is a significant PQQ benefit for men and women in active lifestyles.
  • Powerful Antioxidant Protection: Offers systemic defense against oxidative stress, protecting cells, proteins, and DNA from damage, thereby supporting anti-aging processes throughout the body.
  • Cardiometabolic Health: Supports healthy cardiovascular function and metabolic parameters by improving mitochondrial function in relevant tissues and reducing oxidative stress.
  • Skin Health (Topical & Internal):

 Antioxidant Protection: Shields skin cells from UV and pollution-induced free radical damage, preventing premature aging.

 Supports Collagen: Helps protect collagen and elastin from degradation.

 Anti-inflammatory: Calms skin irritation and redness.

 Promotes Repair: May aid in skin barrier repair and wound healing, improving skin texture and luminosity.

  • Support for Immune Function: Modulates inflammatory pathways and supports healthy immune response.


Application of PQQ Powder

 

1. Dietary Supplements & Nutraceuticals:

 Stand-alone PQQ supplements (common dosages like PQQ 20 mg per serving).

 Synergistic blends with CoQ10 (Ubiquinone or Ubiquinol), creating a powerful combo for mitochondrial and heart/brain health (addressing searches like PQQ vs CoQ10-they are complementary, not competitive).

 Cognitive health formulas, anti-aging complexes, and energy boosters.

2. Functional Foods & Beverages: Added to sports drinks, health bars, and fortified foods for its energy and antioxidant properties.

3. Skincare & Cosmetics: Incorporated into serums, creams, masks, and lotions for its anti-aging, antioxidant, and skin-revitalizing benefits. Ideal for "mito" or cellular-energy-themed skincare (e.g., Mito PQQ products).

4. Sports Nutrition: Included in pre-workout and post-workout recovery formulas to enhance performance and reduce oxidative stress from intense exercise.

 

PQQ Product function diagram

 

Formulation Reference (Guidance)

 

  • Typical Dosage in Supplements: 10-20 mg per day for general support. Always advise consultation with a healthcare provider.
  • Solubility: Highly water-soluble, making it easy to incorporate into liquid formulas, drink mixes, and capsules.
  • Stability: Stable under recommended storage conditions. Protect from prolonged exposure to high heat, light, and extreme pH during formulation.
  • Synergistic Combinations:

 PQQ + CoQ10: For comprehensive mitochondrial and cardiovascular support.

 PQQ + Antioxidants (Vitamin C, E): For enhanced free radical defense network.

 PQQ + Cognitive Agents: For targeted brain health formulations.

 

Frequently Asked Questions (FAQ)

Q: What is PQQ? Is it a vitamin?

A: PQQ (Pyrroloquinoline Quinone) is a powerful, vitamin-like bioactive compound. While not officially classified as a vitamin in humans, it exhibits essential vitamin-like functions, particularly in supporting mitochondrial health.

Q: What are the main PQQ supplement benefits?

A: Key benefits include supporting cognitive function, boosting cellular energy, providing strong antioxidant protection, supporting heart health, and promoting skin vitality.

Q: Are there any PQQ side effects?

A: PQQ is generally well-tolerated at recommended doses. In rare cases, some individuals might experience mild transient effects. As with any supplement, it is crucial to follow dosage guidelines and consult a healthcare professional before use, especially if pregnant, nursing, or on medication.

Q: Can I take PQQ with CoQ10?

A: Yes, absolutely. PQQ and CoQ10 work synergistically. PQQ helps generate new mitochondria, while CoQ10 is essential for the energy production within those mitochondria. They are a powerful combination for overall energy and health.

Q: What is the recommended shelf life and storage?

A: Our PQQ powder has a 24-month shelf life when stored sealed in a cool, dry place (2-8°C ideal), away from direct light and moisture.

 

Three packaging methods

 

★Our packaging method for 1.1 kg and below 1 kg is to pack the powder in Bacteria-free plastic bags first, seal it, and then pack it in aluminum foil bags.

 

★We will pack the 2.25 kg in a large carton. First, we will pack the powder in batches with an Aluminum foil bag, and then put it in the carton for sealing. The other is to directly pack the powder in a transparent bag and put it in a moisture-proof layer, seal it, and then put it in a carton.

 

★25 kilograms can also be packed in wooden barrels, and the packing method is divided into two kinds, like cartons.

Packing

Several ways of shipping

 

Shipping Choices

By EMS/E-Packet

By DHL/TNT/FedEx

By Air

By Sea

Suitable Quantity

Under 5KG

Under 50kg

Under 100kg

More than 100KG

Shipping Time

7-15Days

3-10Days

5-15Days

10-45Days

Shipping Cost

A bit high

High

Low

Lower

Service

Door to Door

To airport

To Port

 

Mode of transport

How to contact us?

 

Ready to enhance your next-generation health or skincare formulations with premium-grade PQQ Powder? Request a FREE sample and a detailed Certificate of Analysis today to verify our quality. Contact our sales team for competitive pricing, formulation support, and to discuss your specific project needs.

 

You can contact us by email: ella.zhang@huilinbio-tech.com, and we look forward to hearing from you.

 

Why choose us?

  • Our success is built on our customers' satisfaction.
  • We rely upon strategic thinking, constant modernisation in all segments, technological advances and of course upon our employees that directly participate in our success for PQQ Powder.
  • Our products and services are designed to meet the needs of your business.
  • Our company has a strong R&D team, constantly innovating in technology, absorbing and introducing international advanced technology, and constantly developing new products.
  • We are experts in the Cosmetic Raw Materials industry.
  • Our ambitious goal of promoting the sustainable development of the industry requires the hand in hand of our partners.
  • We are a Chinese factory that offers professional and high-quality Cosmetic Raw Materials and services.
  • While we are responsible to the country, society and customers, we realize the value of our enterprise and employees, and promote the harmonious development of society.
  • Our products are manufactured using only the finest raw materials available.
  • All of our employees are striving to build our company into a world-class enterprise as soon as possible.

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