Benefits of paeoniflorin extract

Product introduction

Paeoniflorin extract is herb extract powder, Moutan cortex, Chinese traditional medicine name. Dried root bark for peony of Ranunculaceae. Produced in Anhui, Sichuan, Henan, Shandong and other places. Bitter, xin, slightly cold, heart, liver, kidney meridian, with heat cooling blood, blood circulation, remove deficiency heat and other effects. Moutan and moutanol were less toxic.

Small deciduous perennial shrub, 1 to 1.5 m tall. Hypertrophy of rhizome. The branches are short and stout. Leaves alternate, usually 2 to 3 compound; Stalk length 6 ~ 10 cm; Leaflets ovate or broadly ovate, terminal leaflets usually 3-lobed, lateral leaflets also palmately 3-lobed, dark green above, glabrous. Slightly white below, sparsely bearing long white hairs on midrib. Flowers solitary at branch ends, large; Sepals 5, imbricate, green; Petals 5 or most, general cultivars, mostly double petals, great variation, usually obovate, there is a gap at the top, rose, red, purple, white; Stamens many, filaments red, anthers yellow; Pistils 2-5, green, densely short, style short, stigma leaf-like; Disk cup-shaped. Fruit is 2 to 5 follicles of aggregate, oval, green, covered with brown short hairs. Flowering from May to July. Fruit period July to August. Grown in sunny and fertile soil, often in gardens. Distributed in Hebei, Henan, Shandong, Sichuan, Shaanxi, Gansu and other places.

Preparation of paeoniflorin extract

Raw material preparation: fresh Paeonia lactiflora rhizome is selected as raw material, and it is cleaned to remove dirt and impurities on the surface.
Cutting and grinding: cut the cleaned Paeonia lactiflora rhizome into small pieces or fine pieces, so as to better release the effective components. Then, the roots of Paeonia lactiflora are put into a grinder and ground into powder.
Extraction: mix Paeonia lactiflora rhizome powder with appropriate solvent (such as ethanol, water, etc.) to form extract. Different extraction methods can be used, such as soaking, reflux or ultrasonic-assisted extraction. The extraction time and temperature should be determined according to the specific experimental conditions.
Filtering and concentration: filtering the extract through filter paper or membrane to remove suspended solids. The obtained filtrate contains paeoniflorin and other active ingredients. Then, the filtrate is concentrated by a concentrator or a low-temperature concentrator, and the solvent is evaporated, leaving the concentrated paeoniflorin extract.
Crystallization and purification: the purity of paeoniflorin can be improved by crystallization or further separation and purification steps. Commonly used methods include cooling crystallization, solvent crystallization or chromatographic techniques.
Drying and quality inspection: finally, drying the purified paeoniflorin extract to remove the residual solvent. At the same time, appropriate quality detection methods, such as high performance liquid chromatography (HPLC) and ultraviolet spectroscopy (UV), can be used to evaluate the quality of the extract.

White peony extract benefits

1. Cardiovascular effects: Moutan can increase coronary blood flow, reduce cardiac output and reduce left ventricular work in anesthetized canine hearts. It has a significant protective effect on experimental myocardial ischemia, and lasts for a long time, and reduces myocardial oxygen consumption. Sodium moutanol sulfonate could not only inhibit calcium uptake, but also significantly inhibit 45Ca uptake and membrane SA content in calcium abnormal cardiomyocytes, which was dose-dependent. Another model of prey-induced atherosclerosis,

2. Anti-inflammatory effect: Dan skin water decoction diagonal carageen glue edema, adjuvant arthritis and Arthus reaction caused by a variety of inflammatory response inhibition, this rather than inhibit inflammation tissue permeability and restrain PGE2 biosynthesis, cortex moutan cannot suppress residual adrenal compensatory hyperplasia, is no obvious effect on metabolism of adrenal vitamin C, These results suggest that it has neither cortisone-like nor corticotropin-like effects, that is, its anti-inflammatory effects are not dependent on the pituitary adrenal system.

3. Paeoniflorin extract has Antibacterial effect: In vitro experiments show that the cortex moutan decoction on bacillus subtilis, e. coli, salmonella typhi, paratyphoid coli, proteus, pseudomonas aeruginosa, staphylococcus aureus, hemolytic streptococcus, pneumococcus, vibrio cholera, etc all have strong antibacterial activity, the peony leaf decoction for dysentery bacillus, pseudomonas aeruginosa and staphylococcus aureus has a significant antibacterial effect, the effective ingredients of gallic acid. Experiments with chicken embryos have shown that

4.. Anticoagulant effect: In vitro tests on human platelets showed that both Moutan aqueous extract and paeoniflorol could inhibit thromboxane A2 production from platelet arachidonic acid, and then inhibit platelet aggregation, which was the result of inhibiting the cyclooxygenase reaction from arachidonic acid to prostatic H2. The methanol extract of Moutan could inhibit experimental thrombus induced by endotoxin. The results showed that phenol, benzoyl paeoniflorin and benzoyl paeoniflorin could inhibit platelet aggregation, while phenol, paeoniflorin, and paeoniflorin could inhibit opsonin. Benzoyl paeoniflorin has the effect of blocking the activation of fibrin lysogen and anti-fibrin lysozyme. Oxy paeoniflorin, benzoyl oxy paeoniflorin, and benzoyl paeoniflorin have a strong stabilizing effect on the red cell membrane, thus inhibiting thrombosis. Paeoniflorin can inhibit platelet aggregation induced by ADP or collagen by intraperitoneal injection or in vitro.

5. The impact on the immune system: mice gastric cortex moutan, respectively, and were paeoniflorin, paeoniflorin, benzoyl oxide paeoniflorin, can promote the intravenous injection of carbon particles in blood clearance, even if the function of mononuclear macrophage system in the low state also has a promoting effect, microscopic examination see Kupfer cells in the liver and spleen in force enhancement of phagocyte. Paeoniflorin and oxY paeoniflorin can also enhance the phagocytic function of mouse peritoneal macrophages to emulsion in vitro. Intraperitoneal injection of pelagic fluid can increase the number of spots after hemolysis in the spleen of mice. Paeonol intraperitoneally injected into mice 25mg/kg for 6 days can increase spleen weight obviously, and can resist the reduction of thymus weight caused by cortisone and cyclophosphamide. It can be seen from above that moutan can enhance humoral and cellular immunity.

6. Effect on lipid metabolism: Paeonol, paeonol, and paeoniflorin can inhibit the lipolysis of lipids induced by epinephrine. The water extract of the Pelagic cortex can increase glucose to adipogenesis in adipocytes, and obviously increase glucose to adipogenesis induced by insulin.

Characteristics of paeoniflorin extract

Natural source: Paeoniflorin extract is a natural herbal compound extracted from the rhizome of Paeonia lactiflora, and does not contain synthetic or artificially added chemicals. It is widely used in traditional Chinese medicine and health care products.
Multifunctional: Paeoniflorin extract has many biological activities, including anti-inflammatory, anti-oxidation, immunomodulation, anti-tumor and so on. This makes it have a wide application prospect in treating various diseases and promoting health.
Safety: Paeoniflorin extract is generally considered to be relatively safe and has low toxic and side effects. However, it still needs to be used correctly under the guidance of doctors or professionals, especially if you have certain diseases or are taking other drugs.
Antioxidant effect: Paeoniflorin extract is rich in antioxidants, which can neutralize free radicals, slow down the oxidative damage of cells and resist the aging process. This makes it widely used in skin care and anti-aging products.
Good bioavailability: Paeoniflorin extract has good bioavailability and can be effectively absorbed and utilized by the body. This makes it have a relatively high effect in clinical applications.

What fields can paeoniflorin extract be used in?

Traditional Chinese medicine field: Paeoniflorin extract is one of the important components in traditional Chinese medicine, which is widely used in traditional Chinese medicine prescriptions. It is often used to treat inflammatory diseases, gynecological diseases and liver diseases, such as Chuanxiong tea regulating meridians and Siwu decoction regulating qi and blood.
Herbal health care products: Paeoniflorin extract is often used to make herbal health care products, which have the functions of regulating the immune system, antioxidation, anti-inflammation and promoting cardiovascular health. It can be used as health care products or dietary supplements for people to improve their health and prevent diseases.
Skin care products: Paeoniflorin extract is often added to cosmetics and skin care products because of its antioxidant and anti-aging effects. It can help the skin keep young, moist and elastic.
Medical research and development: Paeoniflorin extract, as a natural compound, has many biological activities, so it has potential application value in the field of medical research. Scientists are further researching and developing its application in anti-tumor, anti-inflammatory and immunomodulation.

How to contact us?

We are a company with many years of sales experience in the plant extract industry. After years of operation, we have a series of various products, such as fruit and vegetable powder, cosmetics, tablet candy and other products, and we are a professional raw material supplier. At present, our company is selling paeoniflorin extract in bulk with low price, which is widely used in health care products, medicine, cosmetics and other fields. Those who need to make healthcare products can purchase this raw material. At the same time, since our products are sold directly from the manufacturer, the quality is guaranteed. You can buy with confidence.

If you want to buy or are interested in it, you can go to the international website or send an email to our working email ella.zhang@huilinbio-tech.com. We will reply to you as soon as you see the message. In addition, you can also come to the offline field visit, our company is located in Fengze Science Park, Block B, 170 Yanta District West Street, Xi 'an, Shaanxi Province, Room 706, welcome to your arrival.