Xi'an Huilin Bio-Tech Co., Ltd. is one of the leading manufacturers and suppliers of bitter melon extract charantin powder in China. With abundant experience, we are committed to providing high quality natural products with competitive price. Please feel free to wholesale bulk pure bitter melon extract charantin powder for sale here from our factory.
Products Description
Bitter Melon Extract Charantin Powder is a natural botanical extract derived from the fruit of Momordica charantia (bitter melon), a plant traditionally used as both a vegetable and a medicinal herb across Asia, Africa, and South America. Charantin – the extract's key active compound – is a steroidal saponin that exists as a 1:1 mixture of stigmasterol glucoside (STG) and β-sitosterol glucoside (BSG). It works by stimulating insulin release from pancreatic β-cells, inhibiting gluconeogenesis in the liver, and promoting glucose uptake in peripheral tissues. Our extract is produced through water or ethanol extraction followed by spray-drying, yielding a free-flowing powder that meets food-grade and supplement-grade quality standards. It is widely used in blood sugar support supplements, metabolic health formulas, and weight management products.
Key Features & Advantages
- Standardized Charantin Content – Available in multiple potency grades (1%–25%) with consistent batch-to-batch performance, verified by UV or HPLC
- Water-Soluble Formulation – Easily dispersible in aqueous systems, suitable for capsules, tablets, powders, and functional beverages
- Multiple Extraction Methods – Available as water-extracted (for food applications) or ethanol-extracted (for higher charantin concentration)
- Food-Grade Quality – Produced in GMP-certified facilities with full batch-level COA documentation
- Comprehensive Certification Support – ISO 9001, ISO 22000, HACCP, Kosher, Halal, and FDA-registered
- Versatile Grade Options – Charantin grades from 1% to 25%, with ratio extracts (10:1, 20:1, 50:1) also available
- Customizable Specifications – Custom particle sizes, extraction ratios, and charantin concentrations available upon request
- Flexible MOQ – Orders from 1 kg to support R&D, product trials, and commercial production
Technical Specifications (Typical – 10% Charantin Grade)
| Parameter | Specification | Test Method |
|---|---|---|
| Product Name | Bitter Melon Extract Charantin Powder | - |
| Botanical Source | Momordica charantia L. | - |
| Part Used | Fruit | - |
| CAS Number | 57126-62-2 (Charantin) | - |
| Active Ingredient | Charantin (steroidal saponin mixture) | - |
| Molecular Formula | A: C₃₅H₅₈O₆; B: C₃₅H₆₀O₆ | - |
| Molecular Weight | 574.83; 576.84 | - |
| Appearance | Brownish-yellow to brown fine powder | Visual |
| Odor | Characteristic | Organoleptic |
| Assay (Charantin) | ≥10.0% (UV) | UV |
| Total Saponins | ≥20% | UV |
| Loss on Drying | ≤5.0% | USP <731> |
| Total Ash | ≤5.0% | USP <281> |
| Sieve | 98% pass 80 mesh | USP <786> |
| Solubility | Water-soluble (spray-dried) | - |
| Solvent Residue | Meets Eur. Pharm | USP <467> |
| Pesticide Residue | Negative | USP <561> |
| Total Heavy Metals | ≤10 ppm | ICP-MS |
| Arsenic (As) | ≤1.0 ppm | ICP-MS |
| Lead (Pb) | ≤2.0 ppm | ICP-MS |
| Cadmium (Cd) | ≤1.0 ppm | ICP-MS |
| Mercury (Hg) | Negative | ICP-MS |
| Total Plate Count | ≤1,000 CFU/g | AOAC |
| Yeast & Mold | ≤100 CFU/g | AOAC |
| E. coli | Negative | AOAC |
| Salmonella | Negative | AOAC |
Specifications are for reference. Please request the current COA for batch-specific data.
Health Benefits
Bitter Melon Extract Charantin is a scientifically studied botanical ingredient with benefits supported by traditional use and modern research. Here are the key highlights in simple terms:
1. Supports Healthy Blood Sugar Levels
Charantin, the key active compound in bitter melon extract, helps support healthy blood sugar levels by promoting insulin release from the pancreas and slowing down glucose production in the liver. In a study on hyperglycemic rats, whole fruit bitter melon at 300 mg/kg lowered blood glucose by 31.64% and increased insulin levels by 27.35%.
2. Promotes Insulin Sensitivity
Research shows that charantin-rich bitter melon extract can improve insulin sensitivity by increasing the expression of GLUT4 (a glucose transporter) in skeletal muscle and IRS-1 in the liver. This makes it particularly relevant for type 2 diabetes support.
3. Supports Metabolic Health
Beyond blood sugar support, bitter melon extract helps regulate blood lipids, supports healthy blood pressure, and contributes to overall metabolic wellness.
4. Supports Weight Management
Bitter melon extract is traditionally used to support fat metabolism and healthy body composition. It is a popular ingredient in weight management and diabetic-friendly formulations.
5. Rich in Antioxidants
The extract possesses natural antioxidant properties that help combat oxidative stress – a contributing factor to various chronic conditions.
6. Backed by Traditional Use
Bitter melon has been used as a natural anti-diabetic agent in traditional medicine across Asia for centuries, with its hypoglycemic effects documented in multiple animal models and clinical trials.
Applications
| Application Category | Specific Uses |
|---|---|
| Blood Sugar Support Supplements | Capsules, tablets, and powders for glucose metabolism support; often combined with chromium, cinnamon extract, or berberine |
| Metabolic Health Formulations | Products targeting insulin sensitivity, lipid metabolism, and overall metabolic wellness |
| Weight Management Products | Fat metabolism support formulations, diabetic-friendly weight management supplements |
| Functional Foods & Beverages | Fortified drinks, health teas, and functional foods for blood sugar-conscious consumers (typical use level: 0.05%–5.0%) |
| Pharmaceutical Intermediates | Raw material for anti-diabetic pharmaceutical research and development |
| Animal Nutrition | Feed additives for glucose metabolism support in companion animals and livestock |
Recommended Usage Levels
| Application | Recommended Dosage |
|---|---|
| Dietary Supplements (Capsules / Tablets) | 100–500 mg per serving (depending on charantin grade) |
| Functional Beverages | 0.05% – 0.5% of formulation |
| Functional Foods | 0.1% – 5.0% of formulation |
| Concentrated Formulations | As per formulation requirements |
We recommend conducting stability and efficacy testing for your specific formulation.
Frequently Asked Questions (FAQ)
Q: What is charantin and is it found in bitter melon?
A: Charantin is the primary bioactive compound responsible for the hypoglycemic activity of bitter melon. It exists as a mixture of stigmasterol glucoside and β-sitosterol glucoside in the fruits of Momordica charantia. Research confirms that charantin has anti-diabetic activity comparable to insulin and works by promoting insulin secretion and inhibiting gluconeogenesis. It is the key compound used to standardize bitter melon extracts for supplement and functional food applications.
Q: Is charantin a saponin?
A: Yes. Charantin is classified as a steroidal saponin mixture isolated from Momordica charantia. It is primarily composed of steroidal aglycones and glycosyl moieties. Specifically, charantin is a 1:1 mixture of two steroidal saponins: stigmasterol glucoside (STG) and β-sitosterol glucoside (BSG).
Q: What is the difference between Charantin, total saponins, and bitter melon extract?
A: Charantin is a specific steroidal saponin compound – a 1:1 mixture of stigmasterol glucoside (STG) and β-sitosterol glucoside (BSG). Total saponins refer to the broader group of saponin compounds present in the extract. Bitter melon extract is the full botanical extract containing charantin, saponins, polypeptides, and other bioactive compounds. Our products are standardized to charantin content for consistent potency.
Q: Is Momordica charantia (bitter melon) good for diabetes?
A: Yes. Clinical evidence supports its use as a complementary approach. Studies indicate that bitter melon can help improve blood sugar control and insulin sensitivity, particularly in people with prediabetes and type 2 diabetes. It may be used as a supportive ingredient in blood sugar management formulations, but it should not replace standard medical treatment.
Q: What is the difference between water-extracted and ethanol-extracted bitter melon extract?
A: Water-extracted bitter melon extract is produced using water as the solvent and is more suitable for food and beverage applications. Ethanol-extracted extract typically achieves higher charantin concentrations and is more commonly used for supplement and pharmaceutical applications.
Q: What is Momordicin?
A: Momordicin is a commercial standardized bitter melon extract, not a single chemical compound. The name "Momordicin" is used in the nutraceutical industry as a trademarked product name for extracts standardized to a specific charantin content (typically 10% charantins). Note that "momordicin" also refers to a group of pentacyclic triterpenes (such as 13-hydroxy-28-methoxy-urs-11-en-3-one) that have been isolated from fresh Momordica charantia fruits, but these are distinct from the standardized extract products marketed under similar names.
Q: Can Momordica charantia help with weight loss?
A: Current clinical evidence does not support bitter melon as a stand-alone weight loss agent. While it is a low-calorie, nutrient-dense food that can be part of a healthy diet, studies have not shown significant reductions in body weight, BMI, waist circumference, or body fat percentage. It is best positioned as a supportive ingredient for metabolic health rather than a dedicated weight loss ingredient.
Q: What is the difference between charantin and polypeptide-P?
A: Both are bioactive compounds found in bitter melon (Momordica charantia). Charantin is a steroidal saponin that is orally active and is the preferred compound for oral supplements. Polypeptide-P is an insulin-like protein also found in bitter melon fruit and seeds, but it is destroyed by digestion and requires injection. In terms of health effects, both support blood sugar management, but through different mechanisms: charantin enhances insulin secretion and improves glucose uptake, while polypeptide-P mimics insulin by binding to insulin receptors. Polypeptide-P may also offer antioxidant and anti-inflammatory benefits, but its oral inactivity makes it impractical for supplement applications. Our Bitter Melon Extract Charantin Powder is standardized to charantin for consistent oral efficacy.
Is the product suitable for vegans and vegetarians?
Yes. Our Bitter Melon Extract Charantin Powder is derived from plant sources using food-grade solvents. No animal-derived ingredients are used in the manufacturing process.
Q: Does it contain allergens?
A: Our Bitter Melon Extract Charantin Powder is free from major allergens including gluten, dairy, soy, eggs, fish, shellfish, peanuts, and tree nuts. Allergen declarations are available upon request.
Q: What is the optimal pH range for stability?
A: Bitter Melon Extract Charantin Powder is stable across a broad pH range of 4.0–7.0, making it compatible with most food and supplement formulations.
Q: How should Bitter Melon Extract Charantin Powder be stored?
A: Store in a cool, dry place, protected from light and moisture. Keep containers tightly sealed when not in use. Under these conditions, the product maintains quality for 24 months.
For inquiries, quotations, or sample requests, please contact: sales@huilinbio-tech.com
References
- Mahwish, et al. Bitter Melon (Momordica charantia L.) Fruit Bioactives Charantin and Vicine Potential for Diabetes Prophylaxis and Treatment. Plants. 2021;10(4):730. doi:10.3390/plants10040730.
- Wang HY, Kan WC, Cheng TJ, et al. Differential anti-diabetic effects and mechanism of action of charantin-rich extract of Taiwanese Momordica charantia between type 1 and type 2 diabetic mice. Food Chem Toxicol. 2014;69:347-356. doi:10.1016/j.fct.2014.04.008.
- Isolation, characterization and quantitative HPLC-DAD analysis of components of charantin from fruits of Momordica charantia. Food Chemistry. 2021.
Why choose us?
- We offer competitive pricing options for both wholesale and retail customers.
- Safety production is the foundation of the company's development, so we have always insisted on life first and safety development.
- Our Herbal Extracts are free of contaminants and meet the highest quality standards.
- "Take quality as the foundation, innovation and development", our company aims to build the most competitive high-end Bitter Melon Extract Powder enterprise in China, and strives to build the brand into a national famous brand and famous trademark.
- Our products are Halal and Kosher certified, making them suitable for a wide range of customers.
- Our company has excellent process equipment, strong technical force, excellent product quality, and perfect after-sales service. We sincerely cooperate with our customers to win!
- We have a long-standing reputation as a reliable and trustworthy supplier of Herbal Extracts.
- Integrity, pragmatism, innovation, efficiency is our enterprise spirit, and sincerity is our company philosophy.
- Our company specializes in the production of premium Herbal Extracts with unbeatable prices.
- Through training, teamwork and fulfillment, our employees strive to achieve continuous improvement in all aspects.
Hot Tags: Bitter Melon Extract Charantin Powder, China, suppliers, manufacturers, factory, wholesale, buy, price, bulk, pure, natural, high quality, in stock, for sale, Kelp Extract Powder, Shitake Mushroom Extract Powder, Wild Lettuce Extract Powder, Tongkat Ali Root Extract Powder
