Radix Isatidis Extract Powder

1. Product information

Radix Isatidis Extract Powder, also known as Banlangen extract or Woad Root extract, is a premium botanical concentrate derived from the dried roots of Isatis indigotica Fort., a cruciferous plant. This brown powder is rich in bioactive compounds and has been a cornerstone in Traditional Chinese Medicine for centuries, primarily valued for its properties in clearing heat, detoxifying, and cooling blood. Modern research supports its traditional uses, highlighting a range of pharmacological activities. As a versatile raw material, it is suitable for applications in dietary supplements, functional foods, cosmetics, and pharmaceutical preparations.

2. Basic parameters

3. Documented Benefits & Pharmacological Activities

The benefits of Radix Isatidis are attributed to its complex mixture of bioactive compounds, which work synergistically. The following activities are supported by both traditional use and modern in vitro and animal studies.

• Antiviral & Immunomodulatory Activity: Recognized as a primary traditional use for conditions like colds, fever, and sore throat. Research indicates it can stimulate the immune system and has shown inhibitory effects against various viruses in laboratory studies. Compounds like epigallocatechin and adenosine are closely linked to these effects.
• Antibacterial & Anti-inflammatory Effects: The extract demonstrates broad-spectrum inhibitory activity against bacteria such as Staphylococcus aureus and E. coli. Its potent anti-inflammatory properties help reduce inflammatory responses, which is fundamental to its "heat-clearing" traditional action.
• Antioxidant Activity: The extract and its compounds, such as specific lignans, exhibit significant free radical scavenging ability, helping to protect cells from oxidative stress.
• Research in Other Areas: Laboratory studies have investigated its potential anti-tumor properties (particularly associated with the compound indirubin) and protective effects on the liver. An extract solution has also been studied for managing oral mucositis in cancer patients undergoing radiation.

 Important Note on Clinical Evidence: Memorial Sloan Kettering Cancer Center notes that while promising activities are observed in laboratory studies, "it has not been adequately studied in clinical trials, so it is not known if it works in humans" for many conditions ¹. This highlights the distinction between mechanistic research and proven human efficacy.

4. Primary Application Fields

• Dietary Supplements & Health Foods: Used in capsules, tablets, or as an additive in health teas and functional beverages aimed at supporting immune health and general wellness.
• Cosmetic & Skincare Ingredients: Its anti-inflammatory and antioxidant properties make it a valuable ingredient for soothing skin formulations. Research on Isatidis Folium (leaf) extract shows it can inhibit enzymes that break down collagen, suggesting potential anti-wrinkle and skin-protecting applications.
• Pharmaceutical Preparations: Serves as a key raw material in traditional patent medicines, such as Banlangen Granules, used for respiratory comfort.
• Veterinary and Agricultural Uses: Can be used in veterinary products or as a natural additive in feed.

5. Usage Guidelines & Safety Information

• Suggested Usage: As a raw material, the inclusion rate varies by final product type. In formulations, a common reference is 0.5% to 5%. For finished products like Radix Isatidis tea, traditional decoction methods are used.
• Important Dosage Note: There is a notable lack of large-scale, standardized clinical trials to establish a universally recommended human dosage for Radix Isatidis extract. Appropriate dosage can vary significantly based on the extract concentration (e.g., 10:1, 20:1), the standardized content of active markers (如 epigoitrin), the intended application, and individual factors.
• Safety and Side Effects: Radix Isatidis is generally considered to have low toxicity with a long history of traditional use. Reported side effects are uncommon when used appropriately at common doses. However, it is important to note that compounds in the Isatis plant (like indirubin) may affect how the liver metabolizes certain drugs (acting on cytochrome P450 enzymes such as CYP3A4). Isolated cases of adverse effects, including gastrointestinal discomfort or elevated liver enzymes, have been reported, particularly associated with high doses or prolonged use of concentrated Isatis products.
• Critical Advisory: It is strongly recommended to consult with a qualified healthcare professional or a practitioner trained in herbal medicine before determining a specific dosage for supplemental use. This is especially important for individuals with pre-existing health conditions, those who are pregnant or nursing, or anyone taking prescription medications, due to potential interactions.
• Regulatory Status: This ingredient is listed in the Chinese Pharmacopoeia. For use in supplements or cosmetics in markets like the US, EU, or others, it is the full and sole responsibility of the finished product manufacturer to ensure compliance with all local regulations, conduct appropriate safety assessments, and make lawful label claims.

6. Inspection index

7. Hot product recommendation

8. Packaging and shipping

Use aluminum foil bags and standard cardboard drums, depending on the actual weight purchased by the customer

We use a variety of transportation methods and cooperate with many transportation companies to meet the needs of customers in different regions of the world

9. Quality clause

We are committed to providing high-quality products to customers all over the world. All goods are strictly inspected before being shipped out of the warehouse.

We promise that if the content or colony inspection fails, we will return it for you free of charge. According to years of export experience, no such phenomenon has occurred.

10. About chromatic aberration

All product pictures in our shop are taken in kind, and professional designers correct the color of the pictures according to the product. However, due to different light, angles, and production batches, there will be a slight color difference.

11. Contact us

We are mainly engaged in various animal and plant extracts, cosmetics, supplements, pharmaceutical raw materials, etc. The factory direct sales prices are lower and the quality is guaranteed. If you have any purchasing requirements, please contact us by email: ella.zhang@huilinbio-tech.com

12. References

1. Isatis Root: Purported Benefits, Side Effects & More. Memorial Sloan Kettering Cancer Center.

Why choose us?

• We comply with all relevant industry standards and regulations to ensure the safety and quality of our products.
• We insist on people-oriented, customer-oriented service providers and standardized operation in our management.
• We strive to build long-term relationships with our customers based on trust and mutual respect.
• We believe that enhancing the awareness of conservation is of special significance to the sustainable development of enterprises.
• We are a Chinese factory offering high-quality Herbal Extract products and professional services.
• Our business philosophy emphasizes understanding the real needs of customers, designing products from the perspective of customers, and providing technology and service levels that satisfy customers.
• Our uncompromising attention to detail ensures that every order is perfect for our customers.
• Based on the value war, our company takes the road of independent innovation, and constantly endows the enterprise with brand-new development vitality with its research and development capability.
• We offer comprehensive after-sales services to ensure customer satisfaction.
• We have been dedicated to Isatis Indigotica Fort Extract manufacturing for many years and have profound professionalism, and are known for our professionalism, focus and refinement in R&D and manufacturing.

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