Introduction
Sodium L-ascorbyl-2-phosphate (SLAP) is a highly stable and water-soluble derivative of Vitamin C. Engineered for superior stability, it overcomes the common challenges of pure L-ascorbic acid, such as rapid oxidation and instability in water and air. This advanced form readily penetrates the skin and is efficiently converted by skin enzymes into active, pure L-ascorbic acid, providing a prolonged and effective release of Vitamin C's powerful benefits directly to the cells [1]. It is a cornerstone ingredient for modern, effective, and stable cosmetic and nutraceutical formulations.
Chemical Properties
| Parameter | Specification |
|---|---|
| CAS No. | 66170-10-3 |
| Molecular Formula | C₆H₆Na₃O₉P |
| Molecular Weight | 322.06 g/mol |
| Appearance | White to off-white crystalline powder |
| Assay (HPLC) | ≥ 98.0% |
| Solubility | Highly soluble in water; insoluble in oils |
| pH (1% Solution) | ~7.5 - 9.5 (Neutral to mildly alkaline) |
Mechanism of Action
The efficacy of Sodium L-ascorbyl-2-phosphate lies in its unique "pro-drug" delivery mechanism:
- Stable Delivery: The phosphate group attached to the Vitamin C molecule makes it inherently stable against oxidation from light, air, and heat. This ensures the ingredient remains effective throughout the shelf life of the product.
- Cellular Penetration & Conversion: Due to its water-soluble and stable nature, SLAP efficiently penetrates the skin's layers. Once inside the skin cells (keratinocytes and fibroblasts), ubiquitous cellular phosphatases enzymatically cleave the phosphate group. This process releases pure, active L-ascorbic acid directly at the site where it is needed most [2].
- Prolonged Release: This enzymatic conversion provides a continuous, slow release of active Vitamin C, offering sustained antioxidant protection and collagen synthesis support over time, unlike a single, quick burst from unstable forms.
Key Benefits of Sodium L-ascorbyl-2-phosphate
- Superior Stability: Exceptionally stable in aqueous formulations, preventing the yellowing and degradation common with pure Vitamin C. This extends product shelf life and efficacy.
- Potent Antioxidant Protection: Once converted, it neutralizes free radicals generated by UV exposure and pollution, reducing oxidative stress and preventing premature skin aging.
- Boosts Collagen Synthesis: Stimulates fibroblasts to produce collagen, helping to reduce the appearance of fine lines and wrinkles, and improving skin firmness and elasticity [3].
- Skin Brightening & Even Tone: Inhibits the enzyme tyrosinase, which is crucial in the melanin production pathway. This action helps to fade hyperpigmentation, sun spots, and melasma for a more radiant, even complexion.
- Non-Irritating & Gentle: Its neutral pH and pro-drug nature make it significantly less irritating than acidic forms of Vitamin C (like L-ascorbic acid), making it suitable for sensitive skin types.
Applications in Industry
Sodium L-ascorbyl-2-phosphate Powder is a versatile active for a range of advanced formulations:
1. Cosmetics & Skincare:
Anti-Aging Serums & Creams: For its collagen-boosting and antioxidant properties.
Brightening & Whitening Products: As a key active for treating hyperpigmentation.
Hydrating Toners & Essences: Leveraging its water solubility for lightweight, hydrating layers.
Sunscreen & Day Creams: To provide synergistic antioxidant protection against UV-induced damage.
2. Nutraceuticals & Pharmaceuticals: Used in stable powder sachets, effervescent tablets, and liquid supplements where the stability of Vitamin C is paramount.
3. Hair Care Products: Incorporated into serums and treatments to protect hair from oxidative damage and support scalp health.
Formulation Reference
Basic Stabilized Vitamin C Serum (Water-Based):
1. Water Phase (82%):
Deionized Water: q.s. to 100%
Sodium L-ascorbyl-2-phosphate Powder: 5% (Dissolve completely in water first)
Glycerin: 5%
Butylene Glycol: 5%
2. Actives & Preservatives (3%):
Niacinamide: 2% (Note: Always test compatibility)
Phenoxyethanol & Caprylyl Glycol: 1%
3. Instructions: Dissolve SLAP powder in water with gentle heat if needed. Cool down, then add other water-phase ingredients. Finally, incorporate the preservative. pH is naturally mild, typically requiring no adjustment.
FAQ
Q: How does SLAP differ from L-ascorbic acid?
A: L-Ascorbic Acid is pure Vitamin C but is highly unstable, acidic, and can be irritating. SLAP is a stable, water-soluble, and neutral-pH salt derivative that converts to active Vitamin C inside the skin, offering gentler and more reliable efficacy.
Q: Is this ingredient safe for sensitive skin?
A: Yes, its non-acidic and non-irritating properties make it one of the best Vitamin C derivatives for sensitive skin types. However, a patch test is always recommended.
Q: What is the recommended usage concentration?
A: In cosmetic formulations, typical usage levels are between 0.5% to 5%. A concentration of 3-5% is commonly used for significant antioxidant and brightening effects.
Q: How should I store this powder?
A: Store in a cool, dry place in a tightly sealed container, protected from light and moisture. While stable, proper storage ensures maximum shelf life.
Quality Inspection Sheet
|
Test items |
Specifications |
|
1. Appearance |
White powder |
|
2. Main content： |
≥98.0% |
|
3.PH(3% aqueous solution) |
8.0~10.0 |
|
4.Solubility (10% aqueous solution) |
clear |
|
5.heavy metal (Pb)： |
≤10 ppm |
|
6.arsenic ( As)： |
≤2 ppm |
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Formulate with confidence using our high-purity, stable Sodium L-ascorbyl-2-phosphate Powder. Elevate your skincare and nutraceutical products with a proven Vitamin C derivative. Contact us today to request a sample, a certificate of analysis (CoA), and discuss your specific application needs. Email: ella.zhang@huilinbio-tech.com
References
- Segall, A. I., & Moyano, M. A. (2008). Stability of vitamin C derivatives in topical formulations containing lipoic acid, vitamins A and E. International Journal of Cosmetic Science, 30(6), 453–458.
- Pinnell, S. R., et al. (2001). "Topical L-ascorbic acid: percutaneous absorption studies." Dermatologic Surgery, 27(2), 137-142.
- Lakra, R., Kiran, M. S., & Korrapati, P. S. (2021). Effect of magnesium ascorbyl phosphate on collagen stabilization for wound healing application. International Journal of Biological Macromolecules, 166, 1609-1619.
Why choose us?
- We are a Chinese-based factory that caters to the needs of both suppliers and manufacturers.
- We have a rational optimization of product design, perfect after-sales service to help you effectively improve the operational efficiency and service life of the equipment.
- Our Cosmetic Raw Materials are made to stringent quality standards.
- After years of hard development and continuous growth, we have sold our Sodium L-ascorbyl-2-phosphate overseas and established long-term cooperation with well-known companies.
- Our commitment to customer satisfaction drives everything we do.
- Our company has set up for several years and we have fully utilized our resources in many aspects to develop the technology to cope with our business.
- We use the latest technology to create the highest quality products.
- In the process of operation and business development, we attach great importance to fulfilling our corporate social responsibility.
- Choose us as your supplier and experience the difference of our high-quality products and services.
- We put talents in the height of the company's strategic development to grasp, and provide a wide space for outstanding talents to realize their personal value.
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