L-Glutathione Powder: The Master Antioxidant for Health & Beauty
L-Glutathione Powder, often hailed as the "Master Antioxidant," is a tripeptide composed of three amino acids: glutamic acid, cysteine, and glycine. It exists primarily in its active, reduced form (GSH), which is pivotal for cellular defense and detoxification. As a critical molecule produced naturally in the body, supplemental glutathione is extensively used in nutraceuticals and cosmeceuticals to combat oxidative stress, promote liver health, and support skin brightening. Sourced from high-quality production, our high-purity Glutathione Powder is your key ingredient for formulating cutting-edge health and beauty products [1].
Biophysical & Chemical Parameters
| Parameter | Specification |
|---|---|
| Product Name | L-Glutathione (Reduced) Powder |
| CAS Number | 70-18-8 |
| INCI Name | Glutathione |
| Molecular Formula | C₁₀H₁₇N₃O₆S |
| Molecular Weight | 307.32 g/mol |
| Purity (HPLC) | ≥ 98% |
| Appearance | White crystalline powder |
| Solubility | Freely soluble in water |
Mechanism of Action: The Science of Cellular Defense
Glutathione's unparalleled role stems from its central position in the body's antioxidant network.
- Direct Free Radical Scavenging: As a potent antioxidant, the thiol (-SH) group in its cysteine residue directly neutralizes harmful free radicals and reactive oxygen species (ROS), protecting cells from oxidative damage [2].
- Enzyme Cofactor: It serves as an essential cofactor for several antioxidant enzymes, including Glutathione Peroxidase (GPx). In this role, glutathione reduces peroxides like hydrogen peroxide, converting itself to oxidized glutathione (GSSG) and preventing lipid peroxidation [3].
- Detoxification & Recycling: The Glutathione Reductase enzyme then regenerates GSH from GSSG using NADPH, maintaining a high GSH: GSSG ratio crucial for cellular health. Furthermore, it conjugates with toxins in the liver via Glutathione S-transferase (GST), facilitating their excretion [4].
Key Benefits of Glutathione Powder
- Powerful Systemic Antioxidant: Provides foundational support for the body's entire antioxidant system, reducing oxidative stress linked to aging and chronic conditions.
- Promotes Skin Brightening & Even Tone: Inhibits the tyrosinase enzyme, interrupting the pathway of melanin production, which helps reduce hyperpigmentation and promotes a radiant complexion [5].
- Supports Liver Detoxification: Essential for Phase II detoxification in the liver, it binds to toxins, heavy metals, and pharmaceuticals, making them water-soluble for safe removal from the body.
- Boosts Immune Function: Critical for the optimal function of lymphocytes, enhancing the body's natural defense mechanisms against infections and diseases.
- Anti-Aging & Cellular Health: Helps protect mitochondrial function and repair oxidative damage to proteins, DNA, and cells, supporting overall vitality and longevity.
Application Fields
Our versatile Glutathione Powder is ideal for a wide range of formulations:
- Dietary Supplements: Encapsulated or tabled for supporting liver health, immune function, and overall antioxidant protection.
- Functional Foods & Beverages: Incorporated into health drinks, powders, and fortified foods for daily wellness supplementation.
- Cosmeceutical Skincare: A key active in serums, creams, and masks for its skin-brightening, anti-aging, and antioxidant properties.
- Clinical Nutrition: Used in medical nutrition products for patients requiring enhanced antioxidant and detoxification support.
|
Medical Industry |
Food Industry |
Cosmetics Industry |
Certificate of analysis
|
Item |
Standard |
Test Result |
|
Assay(HPLC) |
98.0%~101.0% |
99.00% |
|
Organoleptic |
||
|
Appearance |
Crystalline powder |
Conforms |
|
Color |
White |
Conforms |
|
Identification IR |
Similar to the reference spectrum |
Conforms |
|
Optical Rotation |
-15.5º ~ -17.5º |
-16.2º |
|
Total Heavy Metals |
≤10ppm |
Conforms |
|
Arsenic |
≤1ppm |
Conforms |
|
Sulfates |
≤300ppm |
Conforms |
|
Ammonium |
≤200ppm |
Conforms |
|
Iron |
≤10ppm |
Conforms |
|
Residue on ignition |
≤0.1% |
0.01% |
|
Loss on drying |
≤0.5% |
0.2% |
|
Related substances |
||
|
Gross contamination |
≤2.0% |
0.7% |
|
GSSG |
≤1.5% |
0.1% |
|
Conclusion |
Conforms to the USP41 standard. |
Frequently Asked Questions (FAQ)
Q: What is the difference between Reduced (GSH) and Oxidized (GSSG) Glutathione?
A: Reduced Glutathione (GSH) is the active, antioxidant form that makes up the vast majority in healthy cells. Oxidized (GSSG) is the form after it has donated an electron. Our product is high-purity Reduced Glutathione, ensuring optimal biological activity.
Q: Is orally supplemented Glutathione effective?
A: Yes. While bioavailability can be a challenge, studies using high-purity, well-formulated glutathione (especially in combination with enhancers like Vitamin C) have shown significant increases in blood levels and clinical benefits for skin and liver health [5].
Q: Can Glutathione be used with other ingredients like Vitamin C?
A: Absolutely. Vitamin C helps recycle oxidized glutathione back to its active form (GSH), creating a synergistic antioxidant effect. It also pairs well with other antioxidants and N-Acetyl Cysteine (a glutathione precursor).
Q: What is the recommended dosage for formulations?
A: Dosage varies by application. In dietary supplements, common daily doses range from 250-500 mg. In cosmetic serums, usage levels of 2-5% are typical. We recommend consulting safety and efficacy data for your target market.
Q: How should the raw powder be stored?
A: Store in a sealed container in a cool, dry, and dark place. For long-term stability, refrigeration is recommended to prevent oxidation and maintain potency.
OEM/ODM Service
|
Powder |
1kg, 2kg, 5kg,10kg/bag; 15kg,20kg, 25kg/Carton; or as your requirement |
|
Subpackage |
10g, 50g, 100g, 200g,500g, or as your requirement |
|
Capsule |
300mg,500mg, or as your requirement. |
|
Tablet |
500mg, 1000mg, or as your requirement. |
Packing and Shipping
Packing: 1kg, 2kg, 5kg/bag, 10kg/carton. 25kg/drum
Shipping methods:
Express (DHL. FedEx, TNT, UPS, EMS): Less than 50kg, Faster and convenient, door to door service, easier to the customs clearance.
By air: 50 to 500kgs, faster and convenient, ship to airport
By sea: More than 500kgs, slower but cheap, ship to port.
Factory Equipment
Huilin Biotech has a factory which is located in No.3-706, Fengze Science Park, No.170 west Dajie, Xi 'an High-tech Zone. Our company is a collection of research and development, production, agent, sales as one of the high-tech enterprises. The company has a strong technical force, advanced technology, and production equipment to provide high-quality products for the world is our permanent pursuit.
Why Choose Huilin
☑ We know customers better.
☑ We know products better.
☑ We know technology better.
☑ We intend to provide more value for you.
☑ We have more patience.
☑ We are happy to listen to you.
☑ We wish multure development with you.
contact us
Empower your health and beauty formulations with the scientifically-proven power of the Master Antioxidant. L-Glutathione Powder is your trusted ingredient for delivering real results in detoxification, skin brightening, and cellular defense.
Contact us today to request a certificate of analysis, discuss your project needs, and get a competitive quote. Email: ella.zhang@huilinbio-tech.com
References
- Pizzorno, J. (2014). Glutathione! Integrative Medicine: A Clinician's Journal, 13(1), 8–12.
- Forman, H. J., Zhang, H., & Rinna, A. (2009). Glutathione: overview of its protective roles, measurement, and biosynthesis. Molecular Aspects of Medicine, 30(1-2), 1–12.
- Brigelius-Flohé, R., & Maiorino, M. (2013). Glutathione peroxidases. Biochimica et Biophysica Acta (BBA) - General Subjects, 1830(5), 3289–3303.
- Lu, S. C. (2013). Glutathione synthesis. Biochimica et Biophysica Acta (BBA) - General Subjects, 1830(5), 3143–3153.
- Weschawalit, S., et al. (2017). Glutathione and its antiaging and antimelanogenic effects. Clinical, Cosmetic and Investigational Dermatology, 10, 147–153.
Why choose us?
- We are committed to providing our customers with the highest level of service possible.
- Facing the challenges of technology and market competition, our company has always implemented responsibility, principles, and rules as the vane.
- Our success is built on our customers' satisfaction.
- We hope that employees must integrate innovative ideas into every aspect of their work, and constantly improve their innovative ability through continuous learning.
- Our products are manufactured with the utmost care and attention to detail.
- We uphold the purpose of honest service to meet the individual needs of customers to the greatest extent.
- Our commitment to quality is second to none.
- After years of development, we have accumulated rich experience and solid foundation in product application and production technology, making us a diversified professional enterprise for L-Glutathione Powder.
- We strive to ensure our customers always receive top-quality products and services.
- Our eternal pursuits are the attitude of 'regard the market, regard the custom, regard the science' and the theory of 'quality the basic, belief the very first and management the advanced' for L-Glutathione Powder.
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